Facilitating drug discovery against COVID-19
Science A collaboration between EMBL Grenoble and EBRIS scientists led to the characterisation of a new compound with promising activity against SARS-CoV-2 variants.
2023
science
Science A collaboration between EMBL Grenoble and EBRIS scientists led to the characterisation of a new compound with promising activity against SARS-CoV-2 variants.
2023
science
Lab Matters Through the collaborative framework agreement, EMBL and ZEISS aim to accelerate the development of imaging technology to advance life science research.
2023
lab-matters
Announcements, Science Closer collaborations with EMBL-EBI data resources set to further develop and grow this unique rare disease platform.
2023
announcementsscience
Science, Technology and innovation Enabling researchers worldwide to share and analyse pathogen data generated across the world
2023
sciencetechnology-and-innovation
Lab Matters EMBL’s 2022 Annual Report is now available online, including a downloadable ‘Year in Review’.
2023
lab-matters
Lab Matters Three EMBL group leaders and six EMBL alumni were recognised for their contributions to the life sciences.
2023
lab-matters
Events EMBL will celebrate its 50th anniversary in 2024 with a dynamic scientific symposium. The event will share fundamental research that continues to open the way to scientific discoveries.
2023
events
Science, Technology and innovation A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…
2023
sciencetechnology-and-innovation
Lab Matters Wolfgang Huber discusses why research assessment needs reform and how this could make science more diverse, more inclusive, and better
2023
lab-matters
Lab Matters Starts three-year process toward full membership, opening up new opportunities for mutual exchange and collaboration.
2023
lab-matters
Alumni EMBL Rome alumna Urtė Neniškytė returned to her native Lithuania, helping establish the Vilnius University-EMBL Partnership Institute and advance genome-editing technologies there.
2023
alumni
Science, Technology and innovation HoloFood, the first consistent collection of multiomic data about chicken and salmon gut microbiomes, set to enable the development of better animal feeds.
2023
sciencetechnology-and-innovation
Lab Matters The TREC expedition stop in Sopot offered an opportunity to create connections with Polish scientists and citizens around the topics of planetary biology and ocean science.
2023
lab-matters
Lab Matters Sihem Bennour, new head of HR, foresees a deeper culture of information sharing, listening, and problem solving with EMBL staff.
2023
lab-matters
Science Researchers from the Ebisuya Group at EMBL Barcelona have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.
2023
science
Lab Matters Jürgen Bauer talks about translating science into applications with societal benefit, his journey from the lab bench to business development, and technology transfer at EMBL.
2023
lab-matters
Events A recent EMBL conference brought together scientists from various disciplines to conjoin scientific pursuits studying ‘life in context’.
2023
events
Lab Matters Adriana Castillo Caballero talks about her curiosity-driven career, the importance of the people in her life, and her dreams for the future
2023
lab-matters
Lab Matters TREC scientists, outreach specialists, and a crucial support team have been on the road, exploring life at European coasts.
2023
lab-matters
Perspectives, Science EMBL-EBI data resources are being used to deliver thousands of genetic diagnostics to patients every month.
2023
perspectivesscience
Announcements, Lab Matters In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
2023
announcementslab-matters
Events During a visit to the Heidelberg EMBL campus, Minister Petra Olschowski learned about EMBL´s current research programme, its scientific operations and local collaborations, and explored its Imaging Centre and World of Molecular Biology exhibition.
2023
events
Science, Technology and innovation A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
2023
sciencetechnology-and-innovation
Lab Matters EMBL researchers and collaborators have begun an impactful innovation-development journey, thanks to a European Commission ‘IMAGINE’ grant.
2023
lab-matters
Alumni The annual meeting organised by Italian EMBL alumni was held in Turin on 18-19 May, hosted by the University of Turin and the University of Piemonte Orientale (UPO)
2023
alumni
Lab Matters The third meeting between EMBL and SciLifeLab communities took place in Uppsala and focused on data science, aiming at further expanding the collaboration
2023
lab-matters
Lab Matters European Commission and EMBL renew commitment, agree on new areas of cooperation, in new EC DG’s first infrastructure visit since appointment.
2023
lab-matters
Alumni From biking together while at EMBL to assistant professorships at Heidelberg University, two academics soon formed a union that took them to the United States., into various industry positions, and now to a life with two young children.
2023
alumni
Lab Matters Martin Pelosse, Scientific Expert at EMBL Grenoble Eukaryotic Expression Facility, explains the platform’s role in supporting the site’s cutting-edge research activities and its future applications.
2023
lab-matters
Lab Matters, Research highlights Postdoctoral researcher Carolin Sauer is leveraging long-read sequencing to develop new detection methods for various cancers.
2023
lab-mattersresearch-highlights
Lab Matters Timothy Shayers talks about his role in overseeing the renovation works at EMBL Rome, his past experiences around the world, and his personal passions.
2023
lab-matters
Lab Matters First published in 1999 as a black-and-white printed newsletter for EMBL staff and alumni, EMBLetc. has undergone many transformations in its 24 years of existence.
2023
lab-matters
Lab Matters EMBL´s new permanent exhibition ‘The World of Molecular Biology’ in Heidelberg is now open for registration. The exhibition takes the visitor on a journey of scales, from genomes to ecosystems, and introduces key imaging technologies.
2023
lab-matters
Announcements, Science The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.
2023
announcementsscience
Science EMBL Hamburg scientists have contributed to the development of the Spitrobot, a ground-breaking experimental setup that will simplify creating molecular movies. The Spitrobot automates the sample preparation for time-resolved crystallography, which is used to create 3D snapshots of protein…
2023
science
Lab Matters Dey Group holds second annual ‘labbatical’ to step outside daily research tasks with the help of single-celled model organisms.
2023
lab-matters
Lab Matters Vizgen, the life science company dedicated to improving human health by visualising single-cell spatial genomics information, has joined EMBL’s Corporate Partnership Programme.
2023
lab-matters
Announcements, Lab Matters EMBL-EBI is making a key contribution to a historic effort to understand the function of every human gene
2023
announcementslab-matters
Lab Matters The Nordic EMBL Partnership for Molecular Medicine celebrates the signing of its renewed ten years agreement between EMBL and the Universities of Aarhus, Oslo, Umeå, and Helsinki.
2023
lab-matters
Lab Matters Croatian scientists and students from the Ruđer Bošković Institute and University of Zagreb visited EMBL to exchange ideas with researchers and public outreach experts on ways to increase interest, awareness, and involvement in science.
2023
lab-matters
Events On Friday 21 April 2023, EMBL held a graduation ceremony to celebrate its newest group of PhDs who graduated during the last 12 months. The graduating class comprised 43 fellows representing 17 nationalities and all six EMBL sites.
2023
events
Lab Matters, Perspectives On the 20th anniversary of the Human Genome Project, we look back at its history, wonder and potential.
2023
lab-mattersperspectives
Lab Matters EMBL Hamburg partners with the Hanseatic Life Science Research Infrastructure Consortium (HALRIC) to enhance life sciences research in Scandinavia and northern Germany. The consortium builds on the HALOS project to foster collaborations between industry, hospitals, and universities, leveraging…
2023
lab-matters
Lab Matters Angelika Thomasson, administrative assistant at EMBL Grenoble, talks about her role in supporting her colleagues in organising events and travels, what she enjoys about EMBL, and which famous female scientist she would like to have coffee with.
2023
lab-matters
Lab Matters Nikon Europe has intensified its engagement with EMBL's Corporate Partnership Programme to support young scientists.
2023
lab-matters
Alumni Alumnus Thomas Graf reflects on his time at EMBL, offering an update on his whereabouts and advice for young scientists.
2023
alumni
Lab Matters Eduard Avetisyan leads the EMBL Hamburg IT team. He joined EMBL after transitioning from particle physics research to IT. Besides providing standard IT user support, his team also enables smooth processing and computational analysis of structural biology data. Here, he talks about the joys and…
2023
lab-matters
Lab Matters, Perspectives Scientists have the technology to edit the human genome. But when should they, and who contributes to these decisions?
2023
lab-mattersperspectives
Research highlights, Science EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.
2023
research-highlightsscience
EMBL Member States, Lab Matters Europe’s life sciences laboratory EMBL on 5 April welcomed Council delegates Ivana Lagator and Lidija Vukcevic from the Montenegrin Ministry of Science and Technological Development, and University of Montenegro representative Professor Danilo Mrdak, to discuss expanding research and training…
2023
embl-member-stateslab-matters
Events, Science EMBL’s planetary biology flagship TREC expedition has officially started. The new project applies EMBL's expertise and technologies in molecular and cellular biology to current environmental challenges, and connects with a wide range of research disciplines.
2023
eventsscience
Events Upcoming EMBO/EMBL symposium provides a forum to explore how organisms function together, and how they react or adapt to changes at different molecular levels.
2023
events
Lab Matters Home to some of Europe’s most cutting-edge tools in molecular biology, EMBL has long shared its expertise and access to these tools through an extensive repertoire of courses, conferences, seminars, and other training. And now included in this mix is a job shadowing programme at EMBL Imaging…
2023
lab-matters
Lab Matters, Science A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.
2023
lab-mattersscience
Lab Matters Interim head of EMBL Rome Cornelius Gross has been awarded an Advanced grant from the European Research Council (ERC) for his project TERRITORY, aimed at investigating the neural basis of territorial aggression and fear.
2023
lab-matters
Alumni Two former EMBL scientists have been recognised for their outstanding contributions to the fields of science communication and multiple sequence alignment research, respectively.
2023
alumni
Lab Matters Audrey Spielmann, Lab Support Manager, talks about her role in supporting the research done at EMBL Grenoble.
2023
lab-matters
Lab Matters The new group leader is setting up the first purely theory-focused research group at EMBL Barcelona. He aims to understand fundamental biological principles using mathematical models and computer simulations, in close collaboration with experimental researchers across EMBL.
2023
lab-matters
Lab Matters Scientists from EMBL and its French academic partners gathered at EMBL Rome for a workshop to foster collaboration and advance research in neuroscience.
2023
lab-matters
Science Using Oxford Nanopore long-read sequencing, EMBL scientists sequenced a primary childhood brain tumour known as a medulloblastoma, uncovering a novel complex mutation pattern.
2023
science
Lab Matters New group leader Thomas Quail studies the fundamental processes that determine how proteins organise the genome inside a cell.
2023
lab-matters
Lab Matters Together with his team, Gergely Papp pushes the frontiers of technology development in the field of structural biology.
2023
lab-matters
Lab Matters Biological X-ray imaging is an emerging technology that uses X-rays to image tissues or even entire organisms. It will play an important role in EMBL Hamburg’s future service portfolio, and will allow studying life on multiple scales. Team Leader Liz Duke discusses her plans to establish X-ray…
2023
lab-matters
Lab Matters EMBL’s site by the sea completed its fifth year of operations. We look back at some key milestones and achievements since 2017.
2023
lab-matters
Events An annual Corporate Partnership Programme meeting provided a forum for EMBL researchers and industry representatives to discuss mobile labs, planetary biology, and other areas of common interest.
2023
events
Research highlights, Science EMBL-EBI researchers use UK Biobank data to uncover new information about rare diseases of the eye.
2023
research-highlightsscience
Lab Matters EMBL is leading the TREC project: the first pan-European and cross-disciplinary effort to examine life in its natural context.
2023
lab-matters
Lab Matters On the occasion of International Women’s Day 2023, EMBL archivist Maria Papanikolaou discusses the traces left by the women in science who have passed through EMBL, irrevocably changing the organisation in small and big ways.
2023
lab-matters
Perspectives, Science As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
Lab Matters EMBL’s French site was highlighted in a short film presenting its expertise in structural biology research and services.
2023
lab-matters
Lab Matters Physicists, engineers and robotics experts work together in EMBL Hamburg’s Instrumentation Team to design instruments that support structural biology research. The team has finished a transfer robot that facilitates automated handling of protein crystals with care and precision. This will help…
2023
lab-matters
Perspectives, Science Why open data from model organisms is essential for rare disease research.
2023
perspectivesscience
Research highlights, Science Researchers create a network of interacting proteins – or interactome – to aid drug discovery.
2023
research-highlightsscience
Lab Matters, Picture of the week Researchers in the Prevedel Group use photoacoustic spectroscopy setup to test and optimise probes before their usage in mouse neuroscience.
2023
lab-matterspicture-of-the-week
Lab Matters, Perspectives Jo McEntyre talks about data services, open data and a new era for research assessment.
2023
lab-mattersperspectives
Science In a first-of-its-kind study, EMBL researchers have shown how DNA methylation across the genome contributes to the precise regulation of gene expression.
2023
science
Lab Matters The Baltic nation of Estonia has become a full member of EMBL, joining the organisation as its 28th member state.
2023
lab-matters
Lab Matters EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.
2023
lab-matters
Lab Matters EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility offers scientists access to almost all available biophysics technologies. The facility’s staff provides advice and support with experiments and data analysis. The facility is conveniently located just next to the EMBL…
2023
lab-matters
Lab Matters Group Leader Hanh Vu studies ‘immortal’ flatworms that can grow and de-grow to understand better factors that determine organisms’ sizes.
2023
lab-matters
Lab Matters A recent student visitor shares her impressions from visiting EMBL’s Vincent group as we recognise International Day of Women and Girls in Science.
2023
lab-matters
Perspectives, Science Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
Science EMBL researchers are stepping outside the lab and thinking outside the box to understand the basic principles that underlie the development and evolution of organismal characteristics.
2023
science
Lab Matters One of EMBL’s core missions is the development and transfer of scientific know-how and technologies to academia, industry, and commercial entities to facilitate further research, innovations, and commercialisation for the benefit of society at large. Working across Europe, EMBL has partnerships…
2023
lab-matters
Science EMBL Grenoble scientists provide new insights into the function of an essential RNA editing enzyme.
2023
science
Announcements, Science Funding awarded for developing tools to harness marine microbiome data for biotechnological applications and ecosystem services.
2023
announcementsscience
Perspectives, Science Genomic sequencing and big data analysis are two novel technologies driving researchers’ understanding of the complexities of cancer.
2023
perspectivesscience
Science New artificial intelligence tool adds speed and detailed cellular information to analysis of cryo-electron tomography to aid researchers’ understanding of inner cell workings.
2023
science
Lab Matters EMBL Rome group leader Jamie Hackett receives EUR 2 million for the ModLogic project, aimed at understanding how chromatin modifications impact gene activity.
2023
lab-matters
Lab Matters New agreement with UN organisation will enable cooperation in the fields of open science, capacity building, and talent development
2023
lab-matters
Science, Technology and innovation Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencetechnology-and-innovation
Lab Matters EMBL hosts inaugural meeting for major interdisciplinary project designed to boost understanding of ocean life
2023
lab-matters
Lab Matters The group leader, together with three other principal investigators, has been awarded the ERC Synergy Grant, one of the most prestigious public grants in Europe.
2023
lab-matters
Lab Matters, Picture of the week Tasmanian flatworms add to an EMBL researcher’s collection as she studies principles that control animal body size.
2023
lab-matterspicture-of-the-week
Lab Matters, Picture of the week Mucus present in the mouse colon can be visualised using Alcian blue staining, as imaged here by EMBL predoctoral fellow Linda Decker.
2023
lab-matterspicture-of-the-week
Perspectives, Science We look back through some of the 2022 highlights from the Darwin Tree of Life project.
2023
perspectivesscience
Lab Matters Rob Finn, one of the co-chairs of the Microbial Ecosystems theme, discusses his work, the challenges of multidisciplinary research, and how the theme is already helping to promote the exchange of scientific ideas.
2023
lab-matters
Science EMBL Grenoble researchers have investigated the interaction between THC and some proteins it might bind to. In a recent study, they showed in vitro that THC inhibits an important human enzyme called autotaxin.
2023
science
Science EMBL Heidelberg researchers and their collaborators reveal how the nuclear pore complex, one of the biggest molecular machines in eukaryotic cells, is assembled one protein at a time.
2023
science
Research highlights, Science A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time.
2023
research-highlightsscience
Lab Matters, Picture of the week Zebrafish embryos during gastrulation, a very early stage of development, to study the effect of temperature on vertebrate embryo development.
2022
lab-matterspicture-of-the-week
Announcements, Science Open data resources that enable global research and development recognised by the Global Biodata Coalition.
2022
announcementsscience
Lab Matters, Picture of the week To identify which drugs disrupt bacterial envelope integrity, the Typas group uses a molecule called chlorophenyl red-β-D-galactopyranoside.
2022
lab-matterspicture-of-the-week
Lab Matters Europe-wide project studies coastal and marine biodiversity from viruses to whales
2022
lab-matters
Lab Matters The Director General of EMBL was elected by her peers to become a member of one of France’s oldest national science academies.
2022
lab-matters
Alumni More than a hundred scientists from across Spain and Europe met at the Andalusian Centre for Developmental Biology (CABD) for the 2022 “EMBL in Spain” event.
2022
alumni
Lab Matters In October 2022, EMBL Grenoble participated in the annual science outreach event Parvis des Sciences, organised by the GIANT campus under the umbrella of the French science week – La Fête de la science.
2022
lab-matters
Research highlights, Science Unveiling a useful tool for understanding human lung development.
2022
research-highlightsscience
Lab Matters EMBL alumnus and eminent molecular biologist Peter B. Becker has been named the next chair of EMBL’s Council as of January 2023.
2022
lab-matters
Lab Matters EMBL’s EIPOD-Learning in Context programme focuses on interdisciplinary research that explores ‘life in context’ and adds a new collaborative dimension with member state organisations.
2022
lab-matters
Science Recent studies supported by EMBL Grenoble’s expertise in structural biology research and scientific services have identified Altiratinib as a potential drug to stop toxoplasmosis infection and opened up treatment options against malaria.
2022
science
Lab Matters The new group leader in Barcelona aims to understand how cells behave in health and in disease, and approaches her favourite hobby, cooking, very similarly to her work in the lab.
2022
lab-matters
Events A recent EMBO|EMBL symposium provided a forum for discussing recent research on a range of issues for organisms as they cope with changing environments.
2022
events
Announcements, Science EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
Lab Matters Three EMBL scientists received this year’s ERC Starting Grants, and will be awarded €1.5 million over five years to carry out research projects.
2022
lab-matters
Lab Matters Looking to understand microbial predator-prey relationships, EMBL’s newest group leader tackles a molecular ‘arms race’ in his lab.
2022
lab-matters
Lab Matters The biannual magazine that highlights EMBL’s research, people, and projects now has a new online home.
2022
lab-matters
Events DANEMO is a communication platform and research support initiative launched by DANDRITE at Aarhus University. It aims to encourage scientists in Denmark to engage with EMBL and EMBO. The DANEMO symposium from 3-4 November in Aarhus focused on raising awareness of the new EMBL programme ‘Molecules…
2022
events
Events EMBL deepens scientific collaboration, opening the door for greater engagement and opportunities for Malta’s life science community
2022
events
Announcements, Science Open Targets announces that Genentech will become the seventh partner in the drug discovery and validation consortium.
2022
announcementsscience
Perspectives, Science Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
Research highlights, Science Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
Research highlights, Science Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
Lab Matters Researchers and engineers have integrated a CrystalDirect harvester into the fully automated beamline MASSIF-1, a unique combination of structural biology technologies that is now open to external academic users.
2022
lab-matters
Announcements, Science Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.
2022
announcementsscience
Science Plankton parasites provide a zombie story perfect for Halloween. While invading single-celled plankton, these parasites devour the cell’s nucleus and hijack metabolism while the organism remains alive.
2022
science
Lab Matters Newly appointed member of the ASAPbio Board of Directors, EMBL Group Leader Gautam Dey speaks about preprints, data management, and open science.
2022
lab-matters
Announcements, Science NIH BRAIN Initiative to fund brain atlases, network coordination, and knowledge sharing to explore brain function research.
2022
announcementsscience
Lab Matters After a postdoc at Weizmann Institute of Science in Israel, Flora Vincent has joined EMBL’s Developmental Biology unit to further explore the world of phytoplankton.
2022
lab-matters
Science EMBL Barcelona researchers have developed a tool that can use light to control the shape of cells .
2022
science
Lab Matters The recent construction of the new ID29 beamline in Grenoble is pioneering a new way of doing experiments in time-resolved crystallography and opening up technology transfer possibilities
2022
lab-matters
Lab Matters The Royal Microscopical Society awarded Ardan Patwardhan and Wim Hagen with Scientific Achievement Award
2022
lab-matters
Events Visit of delegation from the Ruđer Bošković Institute to EMBL Heidelberg marks a new chapter in scientific and institutional cooperation
2022
events
Announcements, Science EMBL-EBI’s MGnify data resource helps researchers find enzymes for novel applications.
2022
announcementsscience
Lab Matters The final pilot project in Iceland marked the countdown to the ‘Traversing European Coastlines’ (TREC) expedition to study coastal ecosystems and their response to changes in the environment.
2022
lab-matters
Science Researchers have combined advanced light microscopy with next-generation sequencing to create a method to study cells directly in the context of their native tissues
2022
science
Events Leading scientific research facilities launch the Health + Life Science Alliance Heidelberg Mannheim. The research alliance aims to build the Rhine-Neckar region into an internationally leading biomedical-technological cluster focusing on life sciences, the health economy, and medical technology.
2022
events
Events EMBL's Partnership Conference highlights the value of its networks, bringing researchers together to build new scientific connections.
2022
events
Lab Matters The institutes have launched a joint new initiative which aims to make biology as engineerable as an aeroplane or a bridge.
2022
lab-matters
Announcements, Science European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
Alumni EMBL´s Inaugural Kafatos Lecture brings outstanding science to the global public. The 2022 lecture will be delivered by EMBL alumnus and distinguished developmental geneticist Denis Duboule and will focus on ‘Evolution and Embryonic Development: The Complex Story of our Dual Origins’.
2022
alumni
Lab Matters EMBL reminds teachers of freely available educational resources and workshops just in time for school.
2022
lab-matters
Science New research by EMBL scientists shows at atomic detail how antibiotics affect the process of protein production inside bacteria.
2022
science
Science Researchers have come up with a way to test the efficacy of hundreds of anticancer drug combinations – simultaneously, rapidly, and accurately.
2022
science
Lab Matters Cell biologist Anthony Hyman and DeepMind’s Demis Hassabis and John Jumper were announced among 25 Breakthrough Prize recipients
2022
lab-matters
Announcements, Science The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsscience
Lab Matters EMBL joined a kick-off event focusing on the developments related to the upgrade of the PETRA III synchrotron storage ring to PETRA IV at the DESY campus, where EMBL Hamburg is located. PETRA IV could open new possibilities at EMBL Hamburg, contributing to the goals of the EMBL Programme…
2022
lab-matters
Lab Matters Dieter Schwarz Foundation renews 3-year funding to EMBL for the EMBL | Stanford Life Science Alliance, a unique international collaboration bringing together researchers from the two leading institutions to develop transformative technologies and accelerate biomedical research.
2022
lab-matters
Science The latest research from EMBL’s Ikmi group employs interdisciplinary approaches to show how sea anemone ‘exercise’ changes their developing size and shape, uncovering an intimate relationship between behaviour and body development
2022
science
Science EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.
2022
science
Lab Matters 20 secondary school students from all over Italy participated in the fourth edition of Summer in Science at EMBL Rome.
2022
lab-matters
Events As the career landscape continues to change for PhDs and postdocs, the EMBL Fellows’ Career Service offers webinars that present professional options in and beyond academia.
2022
events
Lab Matters The Scientific Visitor Programme shares EMBL tools and talent with outside researchers in collaborative, multidisciplinary environments.
2022
lab-matters
Lab Matters A new grant will provide a way for fundamental metabolomic research to realise its commercial potential and promise in aiding drug development and precision medicine.
2022
lab-matters
Science EMBL researchers use a “fearless” computer reconstruction and a two-centuries-old mathematical approach to study limb bud growth.
2022
science
Lab Matters EMBL delegation including the Director General visits Iceland marking another stage in this deepening scientific collaboration
2022
lab-matters
Perspectives, Science Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
perspectivesscience
Lab Matters Virginie Uhlmann, Research Group Leader at EMBL-EBI and one of the co-chairs of the Theory@EMBL transversal theme, chats about how this theme will open up new research avenues.
2022
lab-matters
Research highlights, Science A new method for the robust analysis of copy number variation and used UK Biobank data to identify links between genome and disease.
2022
research-highlightsscience
Research highlights, Science International consortium analyses the genetic sequences and antibiotic susceptibility of 10,000 global Mycobacterium tuberculosis isolates.
2022
research-highlightsscience
Events The EMBL Lautenschläger summer school, held 4–15 Jul 2022, introduced students from a range of scientific backgrounds to interdisciplinary life science research.
2022
events
Science How do gene expression patterns result in the generation of different cell types? Scientists at EMBL Heidelberg used the zebrafish notochord to find out.
2022
science
Science EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
2022
science
Research highlights, Science Machine learning has helped researchers uncover new insights into how bacteria infect host cells.
2022
research-highlightsscience
Science, Technology and innovation AlphaFold database offers a look at 3D protein universe.
2022
sciencetechnology-and-innovation
Events The first meeting of the Latvian Bioinformatics Forum points towards an even brighter future for the country’s role in European life sciences
2022
events
Lab Matters EMBL’s site by the sea hosted a trio of conferences this summer, covering topics ranging from vascular biology to engineered living systems to evolution.
2022
lab-matters
Lab Matters Jan Kosinski, Group Leader at EMBL Hamburg and one of the co-chairs of the Infection Biology theme in EMBL’s new programme, chats about how this theme will support his work and help establish new collaborations.
2022
lab-matters
Lab Matters EMBL’s new archive and records manager, Maria Papanikolaou, explains the dual role she and an additional colleague will have in the Office of Science Information Management.
2022
lab-matters
Science EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.
2022
science
Lab Matters The GEEF facility at EMBL Rome supports scientists worldwide with scientific expertise and state-of-the-art gene editing technologies.
2022
lab-matters
Science Microbial communities play essential roles in ocean ecology and planetary health. A recent publication highlights priorities for understanding and protecting ocean microbiomes.
2022
science
Research highlights, Science Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightsscience
Lab Matters Cornelius Gross, Miki Ebisuya and Nassos Typas join EMBO, the prestigious organisation for the life sciences.
2022
lab-matters
Events Creating a cutting-edge facility for the global life science community doesn't happen overnight. We spoke to some of those who worked to turn this dream into a reality.
2022
events
Events Representatives from politics, industry and academia attended the inauguration ceremony at EMBL Heidelberg
2022
events
Lab Matters Participating researchers will lead projects to develop novel technologies for better science.
2022
lab-matters
Lab Matters EMBL’s 2021 Annual Report is now available, sharing mission highlights from the year in a new digital-first, sustainable format.
2022
lab-matters
Alumni Former chair of EMBL Council to take office as the next President of the Max Planck Society in June 2023.
2022
alumni
Lab Matters EMBL Director General Edith Heard joined other L’Oreal-UNESCO Laureates in Paris for a series of events celebrating these outstanding researchers and their contributions.
2022
lab-matters
Events Researchers from EMBL and CSIC came together to discuss microbial communities, diversity, and behaviour, in the context of One Health.
2022
events
Science EMBL research with Enolase 1 (ENO1) points to a possible new way to understand RNA’s leading role in how cells develop.
2022
science
Events Two days of events with institutes in the country add a new chapter to successful scientific collaboration
2022
events
Science Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…
2022
science
Alumni Two former EMBL staff members have been recognised for their outstanding contributions to research in the fields of brain evolution and cancer.
2022
alumni
Announcements, Lab Matters The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
2022
announcementslab-matters
Lab Matters EMBL and IIT scientists met in person at EMBL Rome to strengthen their collaboration and explore new opportunities for scientific exchange
2022
lab-matters
Lab Matters Pascale Cossart, one of the world’s foremost authorities on the biology of Listeria, brings four decades of expertise in intracellular bacterial parasitism to EMBL as a visiting scientist.
2022
lab-matters
Science Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.
2022
science
Lab Matters A new formal collaboration agreement enables will help smooth the transition from fundamental science to innovation.
2022
lab-matters
Research highlights, Science Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightsscience
Alumni The GSK Vaccines site in Siena hosted the annual EMBL in Italy event. The hybrid meeting brought together industry leaders, representatives from biotech start-ups, data scientists, and researchers from academia.
2022
alumni
Science, Technology and innovation Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencetechnology-and-innovation
Lab Matters Fergal Martin discusses the importance of open access data and his work in different biodiversity initiatives
2022
lab-matters
Lab Matters EMBL Director General Edith Heard has been elected as a foreign member of The Royal Danish Academy of Sciences and Letters in recognition of her academic excellence. Heard is among 15 new members of the Academy, which has been advancing basic research and interdisciplinarity for nearly 280 years.
2022
lab-matters
Events Joint workshop brings researchers together on site and virtually to discuss broad range of planetary biology topics.
2022
events
Lab Matters Students from the Business Academy Aarhus visit EMBL Hamburg annually. Many of them return later as trainees to gain experience as lab technicians. EMBL Hamburg offers great opportunities to learn diverse techniques and work with various equipment. This experience helps them in their future jobs in…
2022
lab-matters
Lab Matters, Perspectives Janet Thornton, the inaugural winner of the FEBS Journal Open Science Award, explains the importance and impact of open science.
2022
lab-mattersperspectives
Science, Technology and innovation How text mining collaborations benefit our research, data resources, and the wider scientific community.
2022
sciencetechnology-and-innovation
Lab Matters Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.
2022
lab-matters
Lab Matters EMBL’s Head of Genome Biology announced as Fellow of the Royal Society for her exceptional contributions to science.
2022
lab-matters
Science Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.
2022
science
Science EMBL researchers revise the old problem of sintering droplets to understand the mechanical properties of tissues.
2022
science
Events EMBL’s first Imaging Centre Symposium will occur onsite at EMBL and include tours of the new Imaging Centre on 31 May, introducing participants to the facility and its staff and featuring talks on the rapid developments in imaging technologies that have led to notable biological and medical…
2022
events
Perspectives, Science Virginie Uhlmann shares her tips for using deep learning for bioimage analysis in the life sciences.
2022
perspectivesscience
Lab Matters The honour recognises distinguished and continuing achievements in original research.
2022
lab-matters
Science Scientists at EMBL Barcelona have created for the first time a 3D in vitro model that recapitulates the periodic formation of human somites – structures that give rise to the spinal column.
2022
science
Lab Matters Professor Kristina Djinović-Carugo has been appointed as the next head of EMBL Grenoble. She will join EMBL in July from the Max Perutz Laboratories at the University of Vienna, where she is currently Head of the Department of Structural and Computational Biology and full Professor of Structural…
2022
lab-matters
Lab Matters Slovenian structural biologist Kristina Djinović-Carugo will join EMBL in July as the new Head of EMBL Grenoble. We spoke to her about her background, research interests, and plans for EMBL Grenoble.
2022
lab-matters
Lab Matters, Perspectives Ewan Birney discusses the input of both genetics and our environment in making us who we are
2022
lab-mattersperspectives
Lab Matters EMBO Director Fiona Watt discusses preprints, data sharing, and evaluation in light of EMBL’s new Open Science policy
2022
lab-matters
Lab Matters EMBL and the Sapienza University of Rome confirm their reciprocal interest in intensifying collaborations and launch new opportunities for exchange of expertise
2022
lab-matters
Science Recent studies from the Hackett group at EMBL Rome have revealed new insights on the mechanism regulating transmission of non-genetic information during embryonic development, and inspired a scientific illustration
2022
science
Research highlights, Science Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightsscience
Lab Matters EMBL Heidelberg’s Matthias Hentze receives the Biochemical Society’s Centenary Award for his discoveries in RNA biology.
2022
lab-matters
Lab Matters John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.
2022
lab-matters
Lab Matters After a two-year break, the summer school organised by Adamas Scienza and EMBL in collaboration with CNR is back. It will take place at the International Research Campus of Monterotondo (Rome) from 13 to 24 June 2022.
2022
lab-matters
Science Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.
2022
science
Perspectives, Science Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivesscience
Announcements, Science Our researchers highlight their contributions to the Darwin Tree of Life project and how new genome annotations helps to further biodiversity research
2022
announcementsscience
Lab Matters Judith Zaugg, Group Leader at EMBL Heidelberg, has been awarded an ERC Consolidator Grant of €2 million funded under the European Union’s Horizon Europe research and innovation programme. Over the next five years, the grant will enable her group to study cellular interactions in the human bone…
2022
lab-matters
Lab Matters EMBL condemns in the strongest terms the unjustified military invasion of Ukraine by the Russian Federation, with the support of Belarus, and the resulting loss of life and human suffering. We express our deepest sympathy to the Ukrainian people and to all the victims of this war. As an…
2022
lab-matters
Perspectives, Science The African BioGenome Project aims to safeguard biodiversity and build bioinformatics capacity across Africa
2022
perspectivesscience
Science EMBL’s imaging technology helps researchers gain insights in the fungus’ journey from the lung to the brain.
2022
science
Science A molecular signature of 27 microorganisms in stool defines the high-risk population for the most common pancreatic cancer and could be used for early detection of the disease.
2022
science
Events EMBL hosted a futuristic infection biology conference, but it offered even more: an opportunity for postdocs to share their work and network towards future research homes.
2022
events
Perspectives, Science Deep learning models can improve protein annotations and has helped expand the Pfam database.
2022
perspectivesscience
Science Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.
2022
science
Science A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.
2022
science
Lab Matters, Perspectives An exploration of what gender bias looks like in science and how organisations and individuals can address it
2022
lab-mattersperspectives
Alumni, Lab Matters New study: EMBL PhDs and postdocs develop skills that make them highly employable in roles that drive research and innovation in academia, industry, and other sectors.
2022
alumnilab-matters
Lab Matters The new permanent ‘The World of Molecular Biology’ exhibition will open in mid-2023 at EMBL’s headquarters in Heidelberg. It will encourage people to actively engage with science and its relevance for everyday life.
2022
lab-matters
Science Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
2022
science
Lab Matters The 11th annual Nordic EMBL Partnership for Molecular Medicine meeting was hosted in virtual format by DANDRITE, the Danish node of the Partnership, from 31 January–2 February 2022. The programme included updates from all partnership nodes, discussions about opportunities for new collaborations,…
2022
lab-matters
Announcements, Science Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementsscience
Lab Matters Michael Dorrity, one of EMBL’s newest group leaders, is studying how the environment influences early life stages in zebrafish.
2022
lab-matters
Announcements, Science Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsscience
Events Agreement signed with Latvia’s Biomedical Research and Study Centre will boost academic exchange and collaboration on some of the largest challenges facing human and planetary health.
2022
events
Alumni, Lab Matters, Technology and innovation Experiences at EMBL Rome led former group leader to establish his start-up in Italy, developing a new generation of gene therapies.
2022
alumnilab-matterstechnology-and-innovation
Science DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
science
Science EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.
2022
science
Events, Lab Matters Ahead of the annual meeting of the Nordic EMBL Partnership for Molecular Medicine, we spoke with its new Speaker, Mark Daly. Mark Daly, FIMM Director, recently accepted the post of Speaker of the Nordic EMBL Partnership. He explains his vision of the future cooperation between EMBL and the Nordics.
2022
eventslab-matters
Perspectives, Science An exploration of where in the world genomics methods are applied and where the data are used.
2022
perspectivesscience
Lab Matters The new EMBL Imaging Centre held its first on-site training workshop, introducing undergraduate students to the basics of volume electron microscopy. This marks the first of many opportunities to aid capacity-building in imaging techniques in Europe.
2022
lab-matters
Science EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
2022
science
Announcements, Science On track to reach an ambitious goal of 3,000 genomes sequenced by the end of 2022, what’s next for the Earth Biogenome Project?
2022
announcementsscience
Announcements, Lab Matters EMBL announces details about its next programme, ‘Molecules to Ecosystems’. It will guide studying life across scales and in context with changing environments.
2022
announcementslab-matters
Science The Galej group at EMBL Grenoble has recently obtained high resolution snapshots of a crucial step in RNA splicing involving the U2 snRNP complex, a crucial component of the human spliceosome.
2022
science
Lab Matters Melissa Harrison joins EMBL-EBI as the new Team Leader of Literature Services. We found out more about her plans for open access publishing and Europe PMC.
2022
lab-matters
Events A delegation from EMBL has participated in inauguration of a new facility — Incubator House — located in Szeged, Hungary.
2022
events
Lab Matters Kristina Haase, Group Leader at EMBL Barcelona, will receive €1.5 million over the next five years to develop her project on 3D vascularised in vitro cardiac tissues.
2022
lab-matters
Science Researchers have identified hundreds of new bacterial species and viruses in the human skin microbiome.
2022
science
Lab Matters This year marks the beginning of EMBL’s next programme ‘Molecules to Ecosystems’ to advance the understanding of life across scales and in the context of changing environments.
2022
lab-matters
Lab Matters The memorandum of understanding (MoU) signed between EMBL and the Institute for Advanced Biosciences (IAB) a year ago has already catalysed new grants for joint research projects related to cancer and infection biology, thereby deepening collaborative activities.
2021
lab-matters
Science EMBL Hamburg’s Kosinski Group, the Beck Laboratory at the Max Planck Institute of Biophysics, and colleagues at EMBL Heidelberg recorded the nuclear pore complex contracting in living cells. They visualised the movement with an unprecedented level of detail with help of new software called…
2021
science
Lab Matters The agreement focuses on reinforcing the collaboration between scientists to strengthen our understanding of the organism in its environment.
2021
lab-matters
Lab Matters Showing a continued commitment to providing a diverse and inclusive organisation for conducting leading molecular biology research, EMBL has launched an Equality, Diversity, and Inclusion (EDI) strategy.
2021
lab-matters
Science Using cryo-EM and structural biology techniques, EMBL researchers have shown how two proteins of Legionella pneumophila interact. This finding sheds light on a mechanism critical to the infection process and could lead to the development of new drugs to treat pneumonia.
2021
science
Science A look back at some of the 2021 highlights from the Darwin Tree of Life partner institutes.
2021
science
Science The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
2021
science
Alumni EMBL alumnus Denis Duboule has been selected as the speaker for the inaugural Kafatos Lecture to take place in October 2022.
2021
alumni
Lab Matters EMBL announces the release of its new Open Science Policy, contributing to positive culture change across the life sciences.
2021
lab-matters
Science Bork Group at EMBL Heidelberg analysed a new global gene database to study how genes emerge and spread across various habitats on our planet. In the future, the group will expand the database and use it for studying microbial gene evolution and dispersal at a finer-grained scale.
2021
science
Science New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.
2021
science
Lab Matters EMBL Senior Scientist and Head of the Genome Biology Unit is among the researchers honoured for outstanding work by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).
2021
lab-matters
Lab Matters EMBL and the French National Centre for Scientific Research (CNRS) signed a memorandum of understanding.
2021
lab-matters
Science Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…
2021
science
Science RNA vaccines, such as the ones for COVID-19, represent a new approach in vaccine technology. Cy Jeffries, faculty staff scientist at EMBL Hamburg, explains the clever technology behind RNA vaccines, and how structural biology contributes to its development. EMBL Hamburg collaborated on several…
2021
science
Lab Matters The new EMBL Imaging Centre has announced its first open user call, and new project evaluation process and training opportunities.
2021
lab-matters
Science EMBL structural biology is part of an international collaboration addressing zoonotic disease caused by Lassa virus.
2021
science
Lab Matters Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.
2021
lab-matters
Events EMBL has taken another step towards strengthening its scientific relationship with Lithuania.
2021
events
Lab Matters Maria Zimmermann-Kogadeeva is one of EMBL’s newest group leaders and a computational biologist whose research group applies computational modelling to better understand the metabolism of gut bacteria and their potential to have far-reaching impacts on other organs.
2021
lab-matters
Lab Matters Tudor Groza joins EMBL-EBI as our new Phenomics Team Lead. We found out from Tudor exactly what this new role will entail
2021
lab-matters
Events The upcoming 22nd EMBL Science & Society Conference will explore the One Health approach, which advocates for greater cross-sectoral collaboration and communication across the human-animal-environment interface.
2021
events
Science How genomics, open data, and multidisciplinary science can improve food security.
2021
science
Alumni An alumnus reflects on the reptile database he started in 1996 while at EMBL. The database helps understand biodiversity issues.
2021
alumni
Lab Matters A new model could serve as a platform to investigate critical placenta barrier phenomena, including defence against bacteria, viruses, and parasites.
2021
lab-matters
Alumni A new life sciences lecture series commemorates the legacy of former EMBL Director General Fotis Kafatos for people around the world.
2021
alumni
Alumni EMBL alum Lara Urban has developed mobile DNA approaches to monitor impacts upon biodiversity in remote areas of New Zealand and elsewhere.
2021
alumni
Lab Matters Correlative microscopy service enables PhD student from Switzerland to study structure and location of proteins cells use to communicate.
2021
lab-matters
Science The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data
2021
science
Lab Matters Independent impact review finds EMBL experimental services are ‘critical’ for research and endorses EMBL as a world-class service provider for academia and industry.
2021
lab-matters
Science A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.
2021
science
Lab Matters EMBL's PhD and postdoc programmes evolve to the more multidisciplinary way of doing great molecular biology research.
2021
lab-matters
Lab Matters Each year, EMBL Hamburg’s Svergun Group offers practical EMBO courses and lecture courses on biological small-angle X-ray scattering (SAXS). The courses provide young scientists an opportunity to gain hands-on experience by measuring their own samples, and by exploring different aspects of SAXS…
2021
lab-matters
Alumni Ken Holmes, outstanding pioneer of structural biology and founder of EMBL´s Hamburg site, died on 2 November 2021 at the age of 87.
2021
alumni
Science What can sponges tell us about the evolution of the brain? Sponges have the genes involved in neuronal function in higher animals. But if sponges don’t have brains, what is the role of these? EMBL scientists imaged the sponge digestive chamber to find out.
2021
science
Science Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
2021
science
Lab Matters Svetlana Dodonova is one of EMBL's newest group leaders, leading a team of researchers who will study how genetic material is organised inside cells using structural biology approaches.
2021
lab-matters
Lab Matters Independent study reveals that EMBL-EBI open data resources are critical for the life sciences.
2021
lab-matters
Lab Matters The engagement of US and European Big Science facilities
2021
lab-matters
Science The Darwin Tree of Life project is an unprecedented initiative sequencing 70,000 species
2021
science
Science International project uses biomolecular data to improve animal feed and make meat production more sustainable
2021
science
Science Using metagenomic data to find novel enzymes for plastic degradation and beyond
2021
science
Lab Matters EMBL attends COP26 to argue for strategy to involve molecular biology in the Green Recovery
2021
lab-matters
Science EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility has released eSPC, an online platform for analysing data from biophysical experiments. The platform enables the scientific community to analyse data from different experiments without the need to travel.
2021
science
Lab Matters A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.
2021
lab-matters
Events EMBL has held a joint workshop with the Belgian Science Policy Office, BELSPO, underlining their long-standing collaboration and commitment to future cooperation.
2021
events
Science The BY-COVID project aims to make infectious disease data, including COVID-19, openly available to everyone.
2021
science
Science Profiling M. tuberculosis strains from 27 countries to reveal causes of drug resistance.
2021
science
Lab Matters Ian Dunham walks us through his career so far including working on the human genome project, seeing his work on the cover of Nature and his current role as Director of Open Targets.
2021
lab-matters
Science Researchers develop a new high-throughput approach to assess the functional significance of protein phosphosites.
2021
science
Lab Matters Professor Edith Heard is among new members elected to US National Academy of Medicine
2021
lab-matters
Science The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…
2021
science
Science Largest in-depth analysis of genomic data tracks the spread of SARS-CoV-2 lineages in England.
2021
science
Science Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…
2021
science
Science If researchers can identify specifically when good cells go bad, they can potentially understand disease better.
2021
science
Lab Matters The two organisations have signed a memorandum of understanding to support scientific cooperation in the exploration of coastal and oceanic ecosystems.
2021
lab-matters
Lab Matters This autumn, students begin their PhD in research groups across EMBL’s six sites.
2021
lab-matters
Events EMBL will host a conference to look at the state of the pandemic, lessons learned, and ways to improve pandemic preparedness. Here’s a sneak peek into what promises to be another interesting and informative EMBL conference.
2021
events
Science Structural biology provides insights into the diverse functions of fibrous protein in humans, amphibians, and bacteria.
2021
science
Science EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
2021
science
Lab Matters A memorandum of understanding (MoU) has been signed between EMBL and the University of Tartu, a leading centre of research and training. The MoU aims to strengthen cooperation between EMBL and the life science research community in Estonia.
2021
lab-matters
Science Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.
2021
science
Lab Matters In the lab, Diënty Hazenbrink works with microbes that live in our guts. In her free time, she enjoys wildlife photography. A shared set of skills facilitates both activities.
2021
lab-matters
Lab Matters EMBL and Hungarian research institutes will collaborate to address urgent biological and environmental challenges.
2021
lab-matters
Lab Matters Hundreds of school children explore the beauty of proteins through art
2021
lab-matters
Science Some of the most amazing creatures live in the deep blue sea. The Mesoscopic Imaging Facility (MIF) at EMBL Barcelona was recently involved in studying one unique feature of the octopus: the ephemeral structures on the surface of their skin called Kölliker’s organs.
2021
science
Lab Matters EMBL and Helmholtz Association have signed a memorandum of understanding. The expanded collaboration of both institutions will focus on research related to health.
2021
lab-matters
Science MOrgAna is an open source, user-friendly, modular software that is able to analyse organoids with machine learning.
2021
science
Research highlights, Science EMBL scientists have found evidence of an unexpected role for retinal cells in pre-processing visual information; their results provide potential opportunity for future prosthetic visual aids.
2021
research-highlightsscience
Science 3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers.
2021
science
Science A research collaboration used machine learning to map tumour molecular make-up, potentially paving way to more customised cancer treatment.
2021
science
Science Packaged for simple installation and free use, the novel method DECODE enables researchers to reduce imaging times and increase localisation density in single-molecule localisation microscopy (SMLM).
2021
science
Alumni Former EMBL Director General Professor Iain Mattaj was awarded the German Cross of Merit (‘Verdienstkreuz 1. Klasse des Verdienstordens der Bundesrepublik Deutschland’) at a ceremony held at EMBL Heidelberg on 9 September 2021.
2021
alumni
Events EMBL's science education department makes the latest scientific research more accessible for teachers and students.
2021
events
Science A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
science
Science In the Mesoscopic Imaging Facility (MIF) at EMBL Barcelona, researchers study the details of biological systems in the context of organs, body parts, or entire organisms. This image shows OPTiSPIM1, one of the custom light-sheet microscope setups available at the facility.
2021
science
Science Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.
2021
science
Lab Matters Giulia Zanetti from the Institute of Structural and Molecular Biology (ISMB) in London explains how the collaboration with the Cryo-Electron Microscopy Service Platform enabled her group to reveal the structure of protein transport complexes.
2021
lab-matters
Lab Matters The new team leader at EMBL Hamburg talks about her plans to establish biological X-ray imaging and high-throughput tomography.
2021
lab-matters
Lab Matters EMBL launches new mentoring opportunity, linking Master’s students with postdoctoral researchers.
2021
lab-matters
Lab Matters EMBL Director General Edith Heard has been elected a member of the German National Academy of Sciences Leopoldina. Her admission to the ‘Human Genetics and Molecular Medicine’ section recognises her outstanding professional contributions to science.
2021
lab-matters
Lab Matters MASSIF-1, run jointly by EMBL Grenoble and the ESRF, is a beamline for macromolecular crystallography. It is used by the research community to study the 3D structure of proteins, which is important for drug development.
2021
lab-matters
Alumni EMBL alumnus Angus Lamond reflects on the process of translating the importance of fundamental research – to EMBL and wider society.
2021
alumni
Alumni A community of scientists is looking at the estimated three billion heart muscle cells in a human heart to better understand heart disease.
2021
alumni
Lab Matters Distinctions recognise Peer’s development and sharing of bioinformatics tools as well as his significant contributions to bioinformatics research, education, and services.
2021
lab-matters
Science Analysis of more than 2 million images has boosted understanding of ocean microbes, shedding light on the distribution of nitrogen-fixers at a global level
2021
science
Science A collaboration led by EMBL Hamburg’s Svergun Group used small-angle X-ray scattering (SAXS) at the European XFEL to obtain data on samples containing coronavirus spike proteins and antibodies that bind them.
2021
science
Science Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
science
Science DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
science
Science A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
science
Science Researchers establish a framework for identifying new drugs capable of exploiting a cell’s own machinery.
2021
science
Lab Matters Mehdi Khadraoui, a former member of the EMBL Communications team, took this close-up of a black redstart.
2021
lab-matters
Lab Matters EMBL Director General Edith Heard has warmly welcomed Fiona Watt, who will become the new director of EMBO.
2021
lab-matters
Alumni EMBL alumni Ilaria Piazza and Ken Holmes have been recognised for their outstanding contributions, and will receive their awards as part of the celebrations for EMBL World Alumni Day.
2021
alumni
Science EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.
2021
science
Science EMBL’s Melissa Graewert and colleagues are taking a structural biologist’s approach to better understanding nanoplastic particles.
2021
science
Alumni We all like a story about rediscovering treasures, right? Well, that’s just what happened recently at EMBL Grenoble!
2021
alumni
Science Research in the Typas group uncovers new details of the strategies Salmonella uses to survive in infected cells.
2021
science
Lab Matters The EMBL Imaging Centre is preparing for external user access, after an on-time and on-budget build and handover to the science team.
2021
lab-matters
Lab Matters EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.
2021
lab-matters
Lab Matters Dr Alexander Aulehla has been appointed the new Head of EMBL’s Developmental Biology Unit, and will take up the role starting in July 2021.
2021
lab-matters
Lab Matters EMBL Director General Edith Heard has warmly welcomed the appointment of Professor Maria Leptin as the next President of the European Research Council (ERC)
2021
lab-matters
Science EMBL Hamburg’s Wilmanns and Kosinski groups have determined the detailed structure of a bacterial protein complex critical for tuberculosis infection.
2021
science
Lab Matters Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.
2021
lab-matters
Events At an EMBL Science & Society lecture, science journalist Kai Kupferschmidt advocated for accurate, clear and contextual science communication.
2021
events
Science After work in antimicrobial resistance, EMBL postdoc Laura Carroll is using machine learning for next-gen antibiotic development.
2021
science
Lab Matters EMBL group leaders Julia Mahamid, Anna Kreshuk & Jonas Ries awarded Chan Zuckerberg Initiative grant to advance what we see inside cells.
2021
lab-matters
Science Researchers investigate how external factors can influence the persistence of microbe species in the human gut
2021
science
Science New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.
2021
science
Lab Matters John Marioni, Alex Bateman, and Takashi Hiiragi have been elected to EMBO Membership.
2021
lab-matters
Lab Matters EMBL is conducting an Impact Assessment of our experimental services to understand the value these services have for our external user community. If you have accessed EMBL experimental services at one or more of our facilities to support the conduct of your research, we would like to hear from you.
2021
lab-matters
Lab Matters EMBL’s EU Green Week event showcased various ways molecular biology research can help solve environmental challenges.
2021
lab-matters
Lab Matters EMBL Director Matthias Hentze describes the Environmental Research Initiative: a community effort to solve global environmental challenges.
2021
lab-matters
Science Under the innovative Planetary Biology research theme, EMBL scientists aim to understand life in the context of its environment.
2021
science
Lab Matters EMBL and the Swedish Science for Life Laboratory sign agreement to advance science together.
2021
lab-matters
Science The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.
2021
science
Science EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.
2021
science
Events EMBL’s most recent Science and Society seminar explored how best to harness big data to address multi-faceted issues of a pandemic.
2021
events
Lab Matters The Gesellschaft für Biochemie und Molekularbiologie has awarded a FEBS Anniversary Prize to Michael Zimmermann for his gut microbiome research.
2021
lab-matters
Events Leading international experts gathered to showcase progress in the fight against COVID-19 and share lessons for the future.
2021
events
Science Researchers at EMBL Hamburg reveal how peg-like proteins clasp and reshape the cell membrane
2021
science
Events A workshop run by EMBL Hamburg explored opportunities for structural biology at the future, upgraded PETRA IV synchrotron.
2021
events
Lab Matters A memorandum of understanding has been signed between EMBL and Inserm to strengthen their scientific cooperation.
2021
lab-matters
Science EMBL scientists have combined artificial intelligence (AI) algorithms with two cutting-edge microscopy techniques.
2021
science
Alumni Zehra Sayers explains what makes the SESAME synchrotron special, why we should not fear failure, and why curiosity is her biggest driver.
2021
alumni
Lab Matters The EMBL-Tara Ocean Foundation collaboration will expand opportunities to jointly explore molecular connections between ocean and humankind.
2021
lab-matters
Science EMBL Hamburg’s integrated structural biology facility has contributed to the success of a large-scale SARS-CoV-2 study
2021
science
Science Researchers reveal the best technology for assembling reference genomes.
2021
science
Lab Matters The European Molecular Biology Laboratory and the Italian Institute of Technology have signed an agreement to expand the scope of their collaboration to include areas of mutual interest and in the context of EMBL’s 2022-2026 Programme “Molecules to Ecosystems”.
2021
lab-matters
Lab Matters EMBL Director General Edith Heard has been elected into the US National Academy of Sciences, recognising her contributions to research.
2021
lab-matters
Science EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
2021
science
Lab Matters Edith Heard has been appointed to a new World Health Organization advisory council.
2021
lab-matters
Lab Matters A memorandum of understanding has been signed between EMBL, Collège de France, and the Institute of Biology of the Ecole Normale Supérieure (IBENS).
2021
lab-matters
Science Researchers identify differences in immune response in asymptomatic COVID-19 cases compared to those with severe symptoms
2021
science
Lab Matters In a talk on 29 April, Professor Jeanette Woolard will share her experience of creating a more positive research culture
2021
lab-matters
Events EMBL and Portugal are bringing together leading scientists to highlight the role of fundamental research in tackling infectious diseases.
2021
events
Science Researchers have used a metagenomics approach to piece together the genomes of yeasts found in wild lichens.
2021
science
Science Scientists from the CABANA project explore how open data is benefiting global research efforts.
2021
science
Lab Matters Florent Cipriani, who recently retired as Head of the Instrumentation Team after a long career at EMBL Grenoble, is one of the pioneers of instrumentation development in this field.
2021
lab-matters
Science Researchers use large-scale human genetic studies to identify drug targets important for managing COVID-19 in its early stages
2021
science
Science Using EMBL Hamburg’s world-class structural biology infrastructure, researchers advance the folding of protein ‘origami’ designed in the lab.
2021
science
Science Researchers have used human medical and genetic data from UK Biobank to investigate the genetics of age-related diseases
2021
science
Lab Matters The challenges and opportunities when setting up a global archive for bioimages
2021
lab-matters
Lab Matters This MoU formalises a 15-year collaboration between the two institutes and strengthens Grenoble as a European research centre in the life sciences.
2021
lab-matters
Science Scientists have determined the structure of Glycine Transporter 1. The finding could open new avenues for developing therapeutics for psychiatric disorders
2021
science
Lab Matters The new group leader at EMBL Rome will study how embryos can inherit non-genetic information from their parents that causes stable and heritable effects
2021
lab-matters
Alumni EMBL alumnus Kai Simons did early work with Semliki Forest virus membranes, which is now central to a COVID-19 vaccine.
2021
alumni
Lab Matters Nassos Typas has received the German VAAM Research Award.
2021
lab-matters
Alumni EMBL alumnus Pawel Masiewicz has transferred skills and experience gained at EMBL to oversee starting materials for mRNA vaccine development.
2021
alumni
Lab Matters The contribution of EMBL Group Leader and Senior Scientist Wolfgang Huber has been recognised by the International Society for Computational Biology
2021
lab-matters
Lab Matters Tracey Brown from Sense about Science shares her thoughts on the need to empower women to share and access scientific information.
2021
lab-matters
Lab Matters Members of EMBL’s Equality, Diversity and Inclusion Committee explain how EMBL is choosing to challenge through its LEAP mentoring programme.
2021
lab-matters
Science Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…
2021
science
Science Thousands of new protein structure models, prected using deep learning, now available to explore
2021
science
Lab Matters EMBL invites Simon Gallow, an advocate at UN Women UK, to give a talk marking International Women’s Day.
2021
lab-matters
Science A new method has the potential to boost international research efforts to find drugs that eradicate cancer at its source.
2021
science
Lab Matters Applications are now open for the Life Science Alliance’s Bridging Excellence Fellowships, enabling postdocs to carry out collaborative projects at EMBL and Stanford University.
2021
lab-matters
Lab Matters EMBL's Environmental Officer Brendan Rouse explains more about his role as a European Climate Pact Ambassador.
2021
lab-matters
Lab Matters As one of EMBL’s newest group leaders, Sinem Saka will combine multiple technologies, such as microscopy and single-cell omics, to solve biological puzzles.
2021
lab-matters
Science A collaboration including EMBL scientists has created the most diverse set of reference human genomes ever assembled.
2021
science
Lab Matters Being a woman in science takes allies, not just great science. Here, EMBL’s L’Oréal–UNESCO Fellows talk about support networks.
2021
lab-matters
Lab Matters Anne Ephrussi has been awarded the German Feldberg Prize 2022 in recognition of her outstanding research.
2021
lab-matters
Lab Matters The Sample Preparation and Characterisation (SPC) Facility at EMBL Hamburg is one of the founding members of the Molecular-Scale Biophysics Research Infrastructure (MOSBRI). Within this new European initiative, the SPC Facility will offer services related to membrane proteins, protein complexes,…
2021
lab-matters
Lab Matters Gautam Dey is fascinated by the evolutionary origins of the nucleus, and is looking forward to making the most of EMBL's infrastructure.
2021
lab-matters
Science Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before
2021
science
Lab Matters Professor Dame Janet Thornton discusses work–life balance, the support she has received during her career, and how organisations can help staff during the COVID-19 pandemic
2021
lab-matters
Science Researchers from EMBL and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei, opening the door for new therapeutics.
2021
science
Science A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.
2021
science
Lab Matters EMBL and EMBRC have signed a memorandum of understanding for increased scientific collaboration.
2021
lab-matters
Lab Matters EMBL Teen Maria-Theresa Licka shares how female scientists guided & inspired her to develop an app to ID vine disease.
2021
lab-matters
Science Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.
2021
science
Lab Matters Roshni Mooneeram discusses what Equality, Diversity and Inclusion (EDI) is to her, and what the meaning of allyship is.
2021
lab-matters
Science New EMBL research shows where & to what degree a component of cellular machinery known as RNA Pol III is mutated and becomes problematic.
2021
science
Science A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
2021
science
Lab Matters Open letter galvanises life science community in support of open COVID-19 data
2021
lab-matters
Science A new lineage of coronavirus was first identified in the UK, but why is it spreading much more rapidly within the population?
2021
science
Lab Matters EMBL and CNR have signed a memorandum of understanding to strengthen scientific cooperation. The agreement will foster collaborative projects and integrate them within the European and global scientific landscape.
2021
lab-matters
Lab Matters The latest issue of Science in School highlights the eight members of EIROforum.
2021
lab-matters
Lab Matters New group leader Nicoletta Petridou explains her fascination with the complexity of early embryo development, and how the interdisciplinary nature of EMBL will aid her research.
2021
lab-matters
Science A note on the coronavirus variant B.1.1.7, which has first been described in the U.K. and has spread to 57 countries. The note summarises epidemiological information about the spread of B.1.1.7 in the U.K. collated and in part conducted by researchers from EMBL-EBI.
2021
science
Lab Matters EMBL and the German Cancer Research Center in Heidelberg are increasing their already existing collaborations with a Memorandum of Understanding between the two institutions.
2021
lab-matters
Science Freshwater sports can cause waterborne infections, but real-time DNA sequencing could help.
2021
science
Events EMBL has a packed schedule of courses and conferences for 2021, ready to go ahead virtually, regardless of limitations on physical gatherings
2021
events
Lab Matters The EMBL Imaging Centre is scheduled to open in 2021 with Timo Zimmermann as Team Leader for advanced light microscopy technology development and service provision.
2021
lab-matters
Lab Matters One of EMBL’s newest group leaders, Olivier Duss, will explore how RNA folds into functional structures and how it works with proteins to control a diverse range of activities in the cell.
2021
lab-matters
Science Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg, in collaboration with scientists in Israel and Spain, have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of…
2021
science
Lab Matters EMBL’s sites in Grenoble, Hamburg, and Heidelberg form the newest Instruct Centre. The new centre offers users access to a broad range of state-of-the-art facilities.
2021
lab-matters
Science Understanding why disagreement is good for COVID science. EMBL Deputy Director General Ewan Birney offers tips for sorting through the discourse.
2021
science
Science Researchers discovered the dominant species of bacteria in kefir grains cannot endure without other species that help the 'team' survive.
2021
science
Lab Matters Schoolchildren create exquisite protein-inspired artworks
2020
lab-matters
Science Despite restrictions, 2020 has been a busy year for the Darwin Tree of Life Project. We take a look at some of this year’s achievements and highlights.
2020
science
Alumni The story of a life-long friendship and a professional partnership that sowed the seeds for a ground-breaking vaccine technology.
2020
alumni
Science Gene activation requires the cooperative activity of multiple transcription factors. Until now, the mechanism used by these factors to coordinate their actions has been poorly understood. EMBL’s Krebs group presents a DNA footprinting method that makes it possible to determine whether…
2020
science
Events December has seen the start of a new chapter in the collaboration that has for years marked the relationship between the European Commission (EC) and EMBL.
2020
events
Lab Matters Facilitated by EMBL’s Scientific Visitor Programme in 2019, Silvia Dias Almeida spent a year in the Diz-Muñoz group, helping solidify her career plans and set her up for a competitive PhD programme in biomedical imaging.
2020
lab-matters
Science A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.
2020
science
Lab Matters Funding by the European Research Council (ERC) will support research on the timing of developmental processes in mammals
2020
lab-matters
Science While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.
2020
science
Science How artificial intelligence can help us solve the mysteries of the protein universe
2020
science
Lab Matters The Chan Zuckerberg Initiative has recognised four EMBL researchers with their most recent awards, showing how tech trailblazers are integral to advancing science and medicine.
2020
lab-matters
Science Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…
2020
science
Science Members of the EMBL community are working to improve our understanding of the parasites that cause malaria and sleeping sickness
2020
science
Science Biotechnology company BioNTech and Johannes Gutenberg University Mainz conduct collaborative research with EMBL scientists at the beamline P12 in Hamburg
2020
science
Science Bioinformaticians at EMBL-EBI and beyond are adapting computational tools to investigate coronavirus genomes and proteins.
2020
science
Events At EMBL’s Science and Society conference, Ugandan campaigner Vanessa Nakate spoke about the need to take action on climate change.
2020
events
Science Microbiomes, plastics, and connectivity – AtlantECO aims to understand the fabric of the Atlantic Ocean.
2020
science
Science Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This information is essential to guide the development of urgently needed therapeutic strategies for suppressing viral replication and induced pathology.
2020
science
Lab Matters EMBL’s Eileen Furlong, Chair of the Equality and Diversity Committee and Head of the Genome Biology Unit, responds to the recent Nature Comms paper on the potential effects of mentor–mentee relationships.
2020
lab-matters
Lab Matters EMBL Director General Edith Heard introduced EMBL’s future plans during a parliamentary event at the Paul-Löbe-Haus of the German Bundestag in Berlin. She shared examples of EMBL’s research and outlined how EMBL’s activities will develop.
2020
lab-matters
Lab Matters Ever-evolving technology and related budgetary, regulatory, and management challenges prompted EMBL to establish its new ARISE fellowship programme, which begins accepting applicants in December.
2020
lab-matters
Science By screening hundreds of sybodies (synthetic mini-antibodies), scientists have identified one that might stop SARS-CoV-2 from infecting human cells. This work, which holds promise for treating COVID-19, was conducted by EMBL Hamburg and collaborators from the Centre for Structural Systems Biology…
2020
science
Science Researchers in the Gross group at EMBL Rome have investigated the mechanism behind defensive behaviour in mice. They have identified a specific area of the brain that encodes both spatial and threat cues to drive location-specific defensive responses.
2020
science
Lab Matters Why should researchers make artificial intelligence more transparent and how can they do it?
2020
lab-matters
Lab Matters EMBL’s Rupert Lück is engaged in developing the European Open Science Cloud (EOSC): the infrastructure that will support the future of data sharing and analysis in Europe.
2020
lab-matters
Science Open access data benefits millions of scientists around the world and is essential for a rapid response to the COVID-19 pandemic.
2020
science
Lab Matters EMBL and CIML have signed a memorandum of understanding that will open up new scientific opportunities.
2020
lab-matters
Events A three-day virtual conference, ‘Gender Roles and their Impact in Academia’, explored how biology, social structures, and unconscious bias shape gender roles, and discussed ways to achieve equal opportunities for men and women in academia.
2020
events
Lab Matters New associate group leader at EMBL Hamburg investigates the structure of functional amyloids in bacteria and in human disease
2020
lab-matters
Science Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…
2020
science
Events Maria Arruda is on a mission to make scientists think more about the role they play in society. After a career in academia and the life sciences, she is trying to help others see the bigger picture when it comes to the responsibility of the scientist.
2020
events
Science Researchers from EMBL Heidelberg have established an automated pipeline to create mutations in genomic enhancers, letting them watch evolution unfold before their eyes.
2020
science
Science A group of scientists led by EMBL Hamburg’s Christian Löw provide insights into the molecular structure of proteins involved in the gliding movements through which the parasites causing malaria and toxoplasmosis invade human cells.
2020
science
Lab Matters On 9 October, EMBL and the Spanish National Research Council (CSIC) signed a Memorandum of Understanding that paves the way for stronger collaboration between these two leading research institutions.
2020
lab-matters
Lab Matters Research facilities play a crucial role in the advancement of science by supporting scientists with specialised expertise and state-of-the-art equipment. The Microscopy Facility at EMBL Rome exemplifies this role by making a wide variety of light microscopy technologies available to its researchers…
2020
lab-matters
Science The genome editing tool CRISPR–Cas9 – which plays a critical role in EMBL’s research – was recognised by the Nobel Prize in Chemistry.
2020
science
Science Members of an EMBL-led research group with collaborators in Estonia and Russia have built and trained a deep learning model to better understand how cells grow and divide.
2020
science
Lab Matters On 8 September, EMBL and Vilnius University Life Sciences Center signed a framework agreement for the establishment of the VU LSC–EMBL Partnership for Genome Editing Technologies.
2020
lab-matters
Events EMBL’s network of alumni plays a vital role in advancing the life sciences globally. EMBL provides research, services, and infrastructure that help former staff to do this effectively. For several years EMBL has been discovering more avenues to help the life sciences across Europe. A key part of…
2020
events
Events The partnership between EMBL and four Nordic research institutions aims to stimulate scientific exchange and inspire scientific collaborations. This year’s conference of the Nordic EMBL Partnership for Molecular Medicine included many talks by EMBL researchers and a presentation by EMBL’s…
2020
events
Events EMBL’s 21st Science and Society Conference will address scientific and societal responses to mass extinctions. Ahead of his keynote speech, renowned palaeontologist Mike Benton explains how looking into the deep past can give us vital insights into the future of life on Earth.
2020
events
Science The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.
2020
science
Events The EMBL conference that explored direct and indirect impacts from the current pandemic on women in science allowed for information and story sharing both in the form of lectures but also via online platforms like Slack and social media that included Twitter.
2020
events
Lab Matters ARISE fellowships to offer first-ever comprehensive training for bioscience infrastructure operations
2020
lab-matters
Science Researchers have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a drug already used to treat acne.
2020
science
Lab Matters A decadal roadmap points the way to cell-based medicine for Europe
2020
lab-matters
Science The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
science
Lab Matters Two EMBL speakers gave presentations that looked toward the future and at ways to trailblaze on the endless frontier of science.
2020
lab-matters
Alumni Erin Tranfield recently joined the EMBL Alumni Association Board as one of 15 newly elected members. Here, she talks about her new role on the board and reflects on how a life-changing event made her refocus her perspective on work and life.
2020
alumni
Lab Matters Maria Bernabeu and Wojciech Galej have each been awarded €1.5 million to research malaria and pre-mRNA splicing, respectively.
2020
lab-matters
Science Scientists from the Beck group have studied the 3D structure of nuclear pores in budding yeast. They show how the architecture of the nuclear pore complex differs inside cells compared to its form observed in vitro studies.
2020
science
Science Researchers have uncovered how cells remove unwanted components from the nucleus following mitosis.
2020
science
Lab Matters EMBL-EBI is one of the eight European institutes involved in the Humanoid Cell Atlas initiative, a new open-access platform that combines single-cell profiling and organoid technology
2020
lab-matters
Science An international group of researchers, led by scientists from EMBL Heidelberg, have discovered that the number of tentacle arms a sea anemone grows depends on the amount of food it eats.
2020
science
Lab Matters As the EMBL Fellows' Career Service program reaches a milestone, it reflects on its first year and looks forward to ways to improve its offerings to EMBL postdocs and predocs.
2020
lab-matters
Science Starting with computer code and moving on to a more user-friendly graphical interface called PlantSeg, the Kreshuk Group at EMBL and collaborators built a simple open-access method to provide the most accurate and versatile analysis of plant tissue development to date.
2020
science
Lab Matters The Head of the Electron Microscopy Core Facility at EMBL Heidelberg receives Mid-Career Scientific Achievement Award 2020
2020
lab-matters
Events More than 500 people have registered for an EMBL conference, "The impact of the COVID-19 crisis on women in science: Challenges and solutions." Scheduled for 9 September, the conference is free and open to all. Pre-registration is still available and required to attend.
2020
events
Lab Matters The EMBL International PhD Programme is one of EMBL’s flagship training programmes. It forms part of our efforts to train and inspire talented scientists to become skilled and creative future leaders. Submission of applications for the current PhD student recruitment round is now possible.
2020
lab-matters
Science The beamlines run jointly by EMBL Grenoble and the ESRF reopen today, unveiling significant upgrades that exploit the brand new fourth generation ESRF synchrotron source.
2020
science
Lab Matters The new team leader offering services in electron microscopy discusses his hopes and plans for the forthcoming EMBL Imaging Centre
2020
lab-matters
Lab Matters The Web Development team provides a central source of web design and development for EMBL’s European Bioinformatics Institute (EMBL-EBI). In July, Geetika Malhotra joined the team as their new Head.
2020
lab-matters
Science An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
science
Science Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
2020
science
Science Researchers studied the spike protein on the surface of the SARS-CoV-2 virus. With its spikes, the virus binds to human cells and infects them. The study gave surprising insights into the spike protein, including an unexpected freedom of movement and a protective coat to hide it from antibodies.
2020
science
Lab Matters As he enters retirement, Head of EMBL Rome Phil Avner reflects on his scientific career and memories from his time as Head of EMBL’s site in Italy
2020
lab-matters
Lab Matters Researchers from all life science disciplines – from fundamental biological research to medical applications – generate immense datasets. Analysing these datasets and gaining new knowledge from them is a growing challenge for scientists. The fields of artificial intelligence (AI) and machine…
2020
lab-matters
Science A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
science
Science The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
2020
science
Science A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce proteins and a unique glimpse into how they respond to antibiotics.
2020
science
Science Europe PMC has begun indexing full-text COVID-19 preprints along with the associated data. The project aims to accelerate research to fight the SARS-CoV-2 virus.
2020
science
Events The Svergun group at EMBL Hamburg has released the course ‘Solution Scattering from Biological Macromolecules’ in an online format for the first time. The course explores different aspects of small-angle X-ray scattering (SAXS) for studying the structure of macromolecules.
2020
events
Science EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into cells.
2020
science
Science Researchers have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours.
2020
science
Science EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
2020
science
Science An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
science
Lab Matters EMBL Director General Edith Heard and EMBO Director Maria Leptin respond to the current proposal on the Multiannual Financial Framework.
2020
lab-matters
Lab Matters European collaboration receives funding to explore risks and impact of future infectious disease outbreaks.
2020
lab-matters
Lab Matters Three changes in senior staff positions have been confirmed at EMBL today. Jessica Vamathevan becomes Head of Strategy, Jan Korbel becomes Head of Data Science for EMBL Heidelberg, and Nassos Typas becomes Senior Scientist.
2020
lab-matters
Lab Matters The European Learning Laboratory for the Life Sciences (ELLS), EMBL’s education facility, invites secondary school science teachers to participate in a virtual training course this autumn entitled ‘Introducing your microbiome’.
2020
lab-matters
Lab Matters Latvia has joined EMBL as a prospect member, starting a three-year process toward full membership.
2020
lab-matters
Lab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.
2020
lab-matters
Lab Matters The CrystalDirect® technology, combined with the web-based CRIMS software enable a fully automated, remote-controlled protein-to-structure pipeline.
2020
lab-matters
Events The virtual EMBL Conference ‘SARS-CoV-2: Towards a New Era in Infection Research’ explored the importance of fundamental research, collaboration, and data science in containing the SARS-CoV-2 pandemic, and discussed opportunities to improve our response to pandemics in the future.
2020
events
Lab Matters EMBL Director General Edith Heard has been elected a senator of the Max Planck Society, one of Germany’s leading scientific research organisations. She joins the Senate along with Nobel Laureates and EMBL alumni Christiane Nüsslein-Volhard and Stefan W. Hell, as well as nine additional new…
2020
lab-matters
Science Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…
2020
science
Lab Matters The governing Council of EMBL has approved Director General Edith Heard’s restructure of senior management with effect from 1 July 2020.
2020
lab-matters
Science A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…
2020
science
Lab Matters Open Targets welcomes new Informatics Science Director
2020
lab-matters
Lab Matters A national consortium including EMBL and the DKFZ is set to launch the German Human Genome–Phenome Archive, creating an invaluable bridge between fundamental biomedical research and applied healthcare.
2020
lab-matters
Science To study how SARS-CoV-2 infects cells, the Gene Editing and Embryology Facility (GEEF) at EMBL Rome will generate mice that express a human version of a protein called ACE2. The mouse line will be shared with preclinical research collaborators carrying out vaccine and antibody trials, and with the…
2020
science
Science Researchers evaluate how the new coronavirus rewires human proteins for its own replication, and identify several antiviral drugs ready for clinical trials
2020
science
Science Today we celebrate the 20th anniversary of the first draft of the entire human genome.
2020
science
Lab Matters EMBL is joining the virtual seminar series ‘Life Science Across the Globe’ – a timely initiative to foster international scientific exchange across countries and continents, starting on 1 July.
2020
lab-matters
Science EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…
2020
science
Science DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
science
Lab Matters EMBL is striving to make its labs and offices a welcoming and inclusive environment for all. To achieve this goal, EMBL's Equality and Diversity Officers, Luisa Vieites Rodrigues and Zac O'Sullivan, are working closely with leadership and the EMBL community. In this interview, they share their…
2020
lab-matters
Lab Matters Jan Korbel and Oliver Stegle have performed a survey of fellow life scientists to learn how the current crisis, with partial or complete institutional shutdowns, is affecting their work.
2020
lab-matters
Events To explore the origins of gender imbalances in academia and possible ways of overcoming them, international experts will meet for the virtual EMBL | EMBO | HHMI conference ‘Gender Roles and their Impact in Academia’ from 13–15 Oct 2020. The conference’s outcomes will be integrated into a…
2020
events
Science While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…
2020
science
Science Scientists at EMBL and Heidelberg University Hospital are studying how the novel coronavirus behaves in the gut to try to better understand its epidemiology and prevent its spread. To do this, they are combining advanced imaging and sequencing technologies to study coronavirus in human intestinal…
2020
science
Lab Matters The European Molecular Biology Laboratory has secured 6.8 million Euros funding from the European Commission to launch a unique training programme. The ARISE Programme will train and develop Europe’s next generation leadership for research infrastructures in the life sciences.
2020
lab-matters
Events The emergence of previously unknown pathogens, such as the novel coronavirus SARS-CoV-2, raises many questions. To explore these questions in an international scientific forum, EMBL will host the virtual conference ‘SARS-CoV-2: Towards a New Era in Infection Research’ on 3 July. Invited…
2020
events
Science Scientists discovered that antihypertensive agent alters the tissue characteristics of colon cancer metastases. This "stiffness" of metastases has an effect on the therapeutic success.
2020
science
Science Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.
2020
science
Science Researchers in the Marcia group at EMBL Grenoble and the De Vivo lab at the Italian Institute of Technology in Genoa have obtained some of the most detailed ever snapshots of the splicing process in systems known as group II self-splicing introns. The new insights will help scientists to develop…
2020
science
Science EMBL researchers are studying COVID-19-related molecules by exposing them to high-brilliance X-ray beams. The Svergun group at EMBL Hamburg is using biological small-angle X-ray scattering (SAXS) as part of a global effort by scientists to elucidate the structural organisation of SARS-CoV-2…
2020
science
Science Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…
2020
science
Science Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…
2020
science
Science Researchers from EMBL Grenoble have developed a way to visualise large RNAs in 3D using biochemical and structural biology techniques.
2020
science
Science EMBL and the European Synchrotron Radiation Facility (ESRF) restart the activities of the Joint Structural Biology Group in Grenoble to support coronavirus-related projects. A new initiative will allow users to be granted access to the High-Throughput Crystallisation (HTX) lab at EMBL and to a…
2020
science
Science EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.
2020
science
Science Scientists hope that a legacy of the novel coronavirus in recovered COVID-19 patients – antibodies in their blood – could lead to drugs to treat others. The Merten group at EMBL Heidelberg has pivoted its microfluidics platform to support the search for neutralising antibodies that could…
2020
science
Science Researchers in EMBL’s Zaugg group have studied the causes of pulmonary arterial hypertension (PAH), a rare disease that causes high blood pressure in the arteries of the lungs. The study, carried out in collaboration with Stanford University School of Medicine, compared lung cells of patients…
2020
science
Lab Matters The nervous system has fascinated Georgia Rapti ever since her first introduction to biology. Her research group in the Developmental Biology unit will focus on understanding the early biological events involved in the nervous system’s formation.
2020
lab-matters
Science Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.
2020
science
Lab Matters EMBL welcomes NetApp, a leader in cloud data services empowering global organisations to change their world with data, as member of the Corporate Partnership Programme of the EMBL Advanced Training Centre.
2020
lab-matters
Science EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…
2020
science
Science The Sample Preparation and Characterisation Facility (SPC) at EMBL Hamburg reopens to support scientists working on Covid-19 research. The SPC Facility is one of the best equipped facilities in Europe is therefore in high demand from external users. Re-opening the facility also allows experts at…
2020
science
Science DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
science
Science By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.
2020
science
Lab Matters The Nordic EMBL Partnership for Molecular Medicine has been awarded 210,000 euros. The funds will be used to train the next generation of specialists and research leaders in molecular medicine in the Nordic countries.
2020
lab-matters
Science The Marquez Team has restarted operations at the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble. The team has developed a fully automated protein-to-structure pipeline, which can be operated remotely and provides virtual access to the facilities.
2020
science
Science EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.
2020
science
Science The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…
2020
science
Science Scientists at EMBL Hamburg and Karolinska Institutet Stockholm aim to find synthetic antibodies – known as nanobodies – that bind a surface protein of the novel SARS-CoV-2 coronavirus. Nanobodies could prevent the virus from entering human cells and causing COVID-19.
2020
science
Science EMBL scientists working in the groups of Matthias Hentze and Wolfgang Huber have created RBPbase – a database of RNA-binding proteins – to assist the identification of proteins that interact with the SARS-CoV-2 RNA genome.
2020
science
Science In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.
2020
science
Events The virtual EMBO | EMBL symposium ‘The Four-Dimensional Genome’ brought together 470 participants. Here, Jürgen Deka, Head of External Scientific Training, discusses how he and his team overcame the organisational challenges.
2020
events
Lab Matters To address global challenges, we need to better understand life in the context of environmental change, says EMBL Director General Edith Heard
2020
lab-matters
Lab Matters Brendan Rouse came to Heidelberg in March as EMBL’s Environmental Officer, tasked with monitoring the organisation’s environmental impact and promoting sustainable practices. Here, he discusses his plans for the new role.
2020
lab-matters
Science Researchers from EMBL Heidelberg have created a complete description of early embryo development, accounting for every single cell in the embryo.
2020
science
Science The new collaborative space will help scientists, public health and healthcare professionals around the world to fight the coronavirus pandemic.
2020
science
Science EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology research.
2020
science
Science Scientists at EMBL Heidelberg are contributing their expertise in a community effort to develop large-scale testing methods for coronavirus. Their goal is to increase the capacity and speed of testing, which is crucial for containing the pandemic.
2020
science
Science EMBL researchers are studying how drugs that have shown good results against COVID-19 work in living cells
2020
science
Science The Protein Expression and Purification Core Facility at EMBL Heidelberg will produce proteins for several coronavirus-related research projects, to assist the development of new strategies to fight the virus.
2020
science
Science EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo
2020
science
Lab Matters EMBL Director General Edith Heard responds to the resignation of the President of the European Research Council (ERC)
2020
lab-matters
Science EMBL scientists examine the molecular causes of a rare hereditary disease of the spine and ribs
2020
science
Lab Matters Three international teams involving EMBL Heidelberg have been granted funding from the European Commission for three Twinning projects with institutes in Portugal and the Czech Republic.
2020
lab-matters
Science The causes of 40 percent of all cases of certain medulloblastoma – dangerous brain tumours affecting children – are hereditary. These are the findings of a recent genetic analysis carried out by scientists from EMBL and numerous colleagues around the world.
2020
science
Lab Matters Bastian Drees is a biophysicist turned librarian, who joined EMBL in January as the new Head of Library. Here, he discusses the changing role of libraries and how they can help scientists organise and share their results.
2020
lab-matters
Science EMBL-EBI set to launch European COVID-19 Data Platform to help store, share, and analyse research data linked to the COVID-19 pandemic.
2020
science
Lab Matters EMBL is committed to providing a safe and healthy working environment for our staff and visitors.
2020
lab-matters
Lab Matters Stories from EMBL’s past are captured via the EMBL Archive’s Oral Histories programme
2020
lab-matters
Alumni Committee recognises outstanding contributions of EMBL alumni to science journalism and genome editing
2020
alumni
Science The Heidelberg-based LeukoSyStem consortium investigates leukaemia stem cells in acute myeloid leukaemia. The German Federal Ministry of Education and Research financially supports this collaboration between Heidelberg University Hospital, HI-STEM gGmbH, the German Cancer Research Center and EMBL.
2020
science
Events How Joana Moscoso bridges the gap between science and society
2020
events
Science EMBL researchers investigate the role of a histone protein in regulating gene expression
2020
science
Science EMBL researchers combine multiple datasets to develop expandable atlas of an entire animal
2020
science
Lab Matters Theresia Bauer and EMBL discuss organisational developments and future strategies
2020
lab-matters
Events Annual Reception celebrates EMBL’s achievements in 2019 and explores its way ahead
2020
events
Lab Matters EMBL’s new Science and Society Manager shares her plans for fostering multidisciplinary dialogue
2020
lab-matters
Science New group leader at EMBL Heidelberg employs synthetic chemistry to develop novel tools for biology
2020
science
Lab Matters 2020 call now open for FNR funding of bilateral projects between EMBL and Luxembourg
2020
lab-matters
Lab Matters EMBL Director General recognised alongside four other exceptional women in the life sciences
2020
lab-matters
Science This technique provides a simple but effective way to study the functions of organs in living animals
2020
science
Lab Matters How EMBL’s ‘Microscope in Action’ introduces teenagers to the basics of fluorescence microscopy
2020
lab-matters
Science Scientists provide important new insights into the molecular basis of X-inactivation
2020
science
Science EMBL co-leads most comprehensive study of genetic causes of cancer
2020
science
Science Cloud computing offers unprecedented opportunities for global-scale research collaborations. It also presents a unique set of challenges in terms of data protection and the ethics of data sharing.
2020
science
Science The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.
2020
science
Science Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.
2020
science
Science Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…
2020
science
Science Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.
2020
science
Science Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer
2020
science
Science Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.
2020
science
Science Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.
2020
science
Science New resource that categorises genes essential for supporting life could be used to identify rare disease mutations
2020
science
Lab Matters Today marks the next chapter in the UK’s relationship with Europe. While we wait to see what a future relationship brings, researchers will continue to work across borders to tackle society’s most pressing problems, such as climate change, ageing, and disease.
2020
lab-matters
Lab Matters New grant will increase collaboration between imaging centres and fuel scientific discovery
2020
lab-matters
Science Strengthening ties between EMBL and Israel through the Scientific Visitor Programme
2020
science
Science New group leader at EMBL Barcelona is investigating how malaria affects the human circulatory system
2020
science
Events László Palkovics, Hungarian Minister for Innovation and Technology, visited EMBL Heidelberg
2020
events
Science EMBL researchers have developed a method to observe interactions between transcription factors
2020
science
Events EMBL Director honoured by the international RNA Society
2020
events
Lab Matters The new EMBL spinoff company Araxa Biosciences GmbH aims to set new standards for the development of antibody-based therapeutics and diagnostics
2020
lab-matters
Events Dame Janet Thornton presents the 2019 EMBL Insight Lecture: Ageing and disease – what is the link?
2020
events
Science Kristina Haase brings an engineer’s perspective to vascular disease and regenerative medicine
2020
science
Lab Matters Judith Reichmann will receive this year’s Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers
2020
lab-matters
Science EMBL scientists identify drug targets in blood and organs
2020
science
Lab Matters The latest issue of the free magazine, Science in School, is now available for teachers worldwide.
2020
lab-matters
Lab Matters The call for applications for Bridging Excellence Fellowships is now open
2020
lab-matters
Events The club provides a social outlet for EMBLers with a social conscience
2020
events
Science Researchers have developed a cheaper and faster method to check for genetic differences in individual cells
2019
science
Science Researchers have developed new methods to reveal the 3D-organisation of bone marrow at a single cell level
2019
science
Science The software diffTF quantifies activity of transcription factors and predicts their mode of action
2019
science
Lab Matters EU funding for iNEXT-Discovery consortium unlocks key technologies for structural biology
2019
lab-matters
Events Celebrating the construction progress with a traditional German ceremony
2019
events
Lab Matters EMBL’s Jan Ellenberg reflects on the process of forming a European research infrastructure
2019
lab-matters
Lab Matters Forty-seven PhD students from all of EMBL’s six sites were celebrated during EMBL’s 2019 Graduation Ceremony on Friday 13 December
2019
lab-matters
Science Resource has implications for disease research
2019
science
Lab Matters EMBL is now a member of the Instruct-ERIC organisation
2019
lab-matters
Lab Matters Professor Eiríkur Steingrímsson will commence his initial one-year term as Chair of EMBL Council on 1 January 2020.
2019
lab-matters
Science A new paper describes a unique mechanism of partner selectivity in transcription factors.
2019
science
Events Unique long-term collaboration agreement to provide new imaging technologies
2019
events
Science Exploring the diverse routes by which EMBL scientists are driving forward neurobiology
2019
science
Lab Matters For many students in the life sciences, finishing a PhD marks a professional crossroads
2019
lab-matters
Science Crick and EMBL PhDs talk science over coffee
2019
science
Science Shedding light on the mechanisms that control the fate of embryonic cells
2019
science
Lab Matters The Szilárd Library celebrates its 40th anniversary on 20 November 2019.
2019
lab-matters
Science A new technique in cryo-EM
2019
science
Events Two recent events have expanded EMBL’s collaboration with one of its newest member states
2019
events
Lab Matters EMBL is a collaborator in four of the projects funded in the first phase of ATTRACT.
2019
lab-matters
Science EMBL researchers have published two new studies involving the nuclear pore complex
2019
science
Science Children's rights stored in synthetic DNA
2019
science
Events On microbiomes, public engagement and not being boring
2019
events
Lab Matters Euro-BioImaging now established as a European Research Infrastructure Consortium
2019
lab-matters
Events Teresa Rodó shares insights from her career in the pharmaceutical industry
2019
events
Events Edith Heard is inaugurated as EMBL Director General
2019
events
Science New possibilities for gene therapies
2019
science
Alumni Nadia Rosenthal describes how she built EMBL Rome’s mouse house
2019
alumni
Lab Matters EMBL career advisors discuss the new portfolio of activities
2019
lab-matters
Events Highlights from the Tara stopovers in Rome, Marseille, and Barcelona
2019
events
Science EMBL’s Genomics Core Facility supports students participating in the annual iGEM competition.
2019
science
Science Funding awarded to EMBL-EBI for tuberculosis monitoring tool
2019
science
Events EMBL at the first annual European Research and Innovation Days
2019
events
Alumni Scientists will discuss the challenges ahead for international science at the EMBL in the USA event.
2019
alumni
Events During the Nacht der Forschung 2019, everyone was able to become a scientist for a day at EMBL
2019
events
Events EMBL joins Tara in Barcelona to promote science and interdisciplinarity
2019
events
Alumni EMBL Barcelona will host the 2019 EMBL in Spain event
2019
alumni
Events From 27–30 September, Tara will be docked in the port of Marseille, France’s second largest city.
2019
events
Events When: Friday, 4 October at 16:30 – 18:00. Where: The press conference will be held on the Tara schooner at the Port Olímpic in Barcelona. What: A press conference on the new Tara mission on microplastics and Tara’s cooperation with EMBL.…
2019
events
Science Researchers from Hamburg simplify time-resolved X-ray crystallography
2019
science
Events What: A press conference on the new Tara mission on microplastics and the Tara Ocean Foundation’s cooperation with EMBL. The press briefing will be followed by a visit to the schooner.When: Friday 27 September at 13:00 CEST.Where: The press conference will be held on the Tara…
2019
events
Science Immunotherapy: the role of B cells
2019
science
Events The next stop on Tara’s journey will be at the mouth of the Tiber
2019
events
Events EMBL-EBI celebrated its 25 anniversary on 1 September 2019
2019
events
Alumni September’s alumni event in Marseille will coincide with a Tara stopover
2019
alumni
Events When: Friday 13 September at 14:30.Where: The press conference will be held on the Tara schooner at the Porto Turistico di Roma (Lungomare Duca degli Abruzzi, 84, 00121 Roma RM, Italy).What: A press conference on the new Tara mission on microplastics and the Tara Ocean Foundation’s…
2019
events
Events The inaugural EMBL Lautenschläger Summer School ran from 15–26 July at EMBL Heidelberg.
2019
events
Science Exploring the cancer genomics labyrinth
2019
science
Alumni Klaus Rajewsky recalls the pioneering spirit of EMBL Rome’s first years
2019
alumni
Science MEG3 adopts a complex three-dimensional structure to fulfil its tumour suppressor function.
2019
science
Science Understanding how ageing works at a molecular level
2019
science
Alumni Bernd-Uwe Jahn, former EMBL Administrative Director, Ministerialrat and Jurist has passed away
2019
alumni
Lab Matters Native Scientist’ organises multilingual science workshops for children of migrant communities.
2019
lab-matters
Events Images by EMBL researchers are included in an art–science exhibition in a Barcelona Metro station.
2019
events
Science Schoolchildren get creative with 3D protein structures
2019
science
Alumni Frank Gannon discusses the strong links between Australia and EMBL.
2019
alumni
Science Eric Karsenti's combined loves of biology and sailing set in motion the Tara Oceans expedition
2019
science
Lab Matters Interview with Janka Motešická: a EUCYS 2018 prize winner
2019
lab-matters
Alumni Dr Cristian D. Magnus discusses LGBTQ+ issues and diversity in science
2019
alumni
Events EMBL Lab Day 2019 filled the ATC with art and games
2019
events
Lab Matters Indrek Reimand discusses the life sciences in Estonia, a prospect member of EMBL.
2019
lab-matters
Science Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions
2019
science
Lab Matters Promotions for Anne Ephrussi, Rainer Pepperkok, Paul Flicek and Jo McEntyre
2019
lab-matters
Events The main funder of the EMBL Lautenschläger Summer School reflects on codes of conduct around giving
2019
events
Science SidJ enforces a unique modification on human proteins and helps legionella grow.
2019
science
Science Michael Zimmermann's group will investigate how gut microbes affect the body’s response to drugs.
2019
science
Events Programme for Heidelberg | Mannheim
2019
events
Events Friends old and new mark the occasion in style
2019
events
Science EMBL scientists collaborate to develop new protocol for screening membrane protein stability
2019
science
Lab Matters Tomasz Smolarek and Natalia Kret in conversation.
2019
lab-matters
Events Funding for EMBL | Stanford Life Science Alliance.
2019
events
Science Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.
2019
science
Alumni The life science community is deeply saddened by the death of Suzanne Eaton
2019
alumni
Science Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.
2019
science
Science How computer processing of human language is harnessed by EMBL scientists
2019
science
Science What CRISPR may bring for the future of biology, and how it is used at EMBL
2019
science
Lab Matters Reflecting on 20 years of EMBLEM
2019
lab-matters
Alumni EMBL alumna Jennifer Deegan built a prize-winning system for photographing ferns
2019
alumni
Alumni The naked mole-rat as a model organism in ageing research
2019
alumni
Lab Matters Setting up a kids coding club - where to start
2019
lab-matters
Science New insights into mechanisms behind embryonic development
2019
science
Science The BioImage Archive - EMBL-EBI's first dedicated imaging data resource
2019
science
Science A conversation about art-science collaborations and the importance of drawing in biology.
2019
science
Lab Matters EIPOD4 will prepare researchers for the increasing interdisciplinarity of scientific career paths
2019
lab-matters
Science The increasing importance of code in the biological sciences
2019
science
Events Nobel prize laureate Susumu Tonegawa describes his work in memory research over the past decade
2019
events
Events The programme promotes education, collaboration and cutting-edge research
2019
events
Lab Matters Joining forces to support early-career scientists
2019
lab-matters
Science Using genomics to help endangered species
2019
science
Events Tara schooner welcomes on board journalists, policymakers, funders and scientists
2019
events
Science The mystery of how condensin maintains the integrity of the genome during cell division.
2019
science
Lab Matters The team at ELLS use Lego to teach children the fundamentals of DNA.
2019
lab-matters
Events EMBL Hamburg and Tara raise awareness of the risks of microplastic pollution and global infection
2019
events
Lab Matters The head of EMBL’s Barcelona site joins a prestigious group of more than 1800 scientists worldwide
2019
lab-matters
Science Uncovering new role of fluid pressure in controlling embryo size and cell fate
2019
science
Lab Matters Lithuania becomes EMBL’s 27th member state
2019
lab-matters
Lab Matters Overwhelmed as a biologist getting to grips with computer programming? EMBLers are here to help!
2019
lab-matters
Events Professor Tim Lewens challenges the human genome’s unique place in bioethics
2019
events
Events When: Monday 17 June at 10:30Where: The press conference will be held on the Tara schooner at the Sandtorhafen in the Hamburg harbourWhat: A press conference on the new Tara mission on microplastics and Tara’s cooperation with EMBL. A tour of the schooner will be organised with the…
2019
events
Science Snapshots of the flu virus replication machine in action
2019
science
Events EMBL got together with the global science festival Pint of Science to explain and celebrate science.
2019
events
Science Tara Ocean Foundation launches the exploration of 10 European rivers
2019
science
Science Scientists develop software tools for automated acquisition of electron microscopy data
2019
science
Lab Matters Edith Heard and Jean-Eric Paquet discuss the future of European science
2019
lab-matters
Lab Matters EMBL success in attracting EU funding
2019
lab-matters
Science A newly developed 3D microscope visualises fast biological processes better than ever.
2019
science
Science Results from the Tara Oceans expedition reveal the Arctic Ocean as a cradle of viral biodiversity
2019
science
Science EMBL scientists have discovered that the proteome is substantially affected by both sex and diet
2019
science
Lab Matters The current and previous Directors General discuss what it means to lead an organisation like EMBL
2019
lab-matters
Science Thorough characterisation of structural variants in human genomes
2019
science
Lab Matters Building bonds between academia and industry
2019
lab-matters
Lab Matters The Nordic EMBL Partnership directors discuss the value of collaborating across borders
2019
lab-matters
Science Large CRISPR screen prioritises hundreds of promising genes for personalised cancer treatment
2019
science
Lab Matters New head of ORD will build and expand the partnerships that help EMBL achieve its ambitions
2019
lab-matters
Lab Matters The Francis Crick Institute and EMBL have agreed to work together to strengthen European science
2019
lab-matters
Lab Matters EMBL’s Plamena Markova reflects on the EMBL Partnership Programme
2019
lab-matters
Events Foundation stone ceremony for world-class high-resolution microscopy centre in Heidelberg
2019
events
Science Colorectal cancer characterised by consistent changes in gut bacteria across continents, cultures and diets
2019
science
Science EMBL scientists create membraneless organelle to build proteins in living cell
2019
science
Lab Matters EMBL begins partnership with Polish centre of excellence for neural plasticity and brain disorders
2019
lab-matters
Lab Matters PDBe-KB - new data resource for protein structure and function launches
2019
lab-matters
Science New EMBL group leader explores what neurobiology can teach us about what it means to be human
2019
science
Events On 20 February, over 250 local supporters and friends met Edith Heard to celebrate a successful year
2019
events
Science Scientists develop technology to measure how ATP concentration affects protein solubility in cells
2019
science
Science New group leader at EMBL Grenoble is investigating the cellular role of melanoma antigens
2019
science
Science Many microbes traverse the oral-gut barrier
2019
science
Alumni Scientists honoured for contributions in cancer immunotherapy and structural biology
2019
alumni
Science How organs form in a mouse embryo
2019
science
Science Suicide system in tuberculosis bacteria might hold key to treatment
2019
science
Science EMBL scientists identify RNA regulating protein behaviour in switch of normal roles
2019
science
Science Researchers identify novel gut bacteria species and call for more data from beyond Europe and North America
2019
science
Lab Matters On 5 February 2019, EMBL welcomed Poland as its 26th member state
2019
lab-matters
Science A new database of bacteria in the human microbiome is the most comprehensive to date.
2019
science
Science New search engine allows researchers to identify antibiotic resistance genes or mutations in real time
2019
science
Science Scientists develop high-throughput yeast single-cell RNA sequencing method
2019
science
Science Scientists develop structural model that could help in the development of drugs with increased absorption rates
2019
science
Lab Matters Enhancing the world's bioinformatics infrastructure
2019
lab-matters
Lab Matters A collection of the most read articles from the EMBL news website in 2018
2019
lab-matters
Science Federated data sharing will now be possible on an unprecedented scale
2019
science
Lab Matters New director drives drug discovery partnership forward
2019
lab-matters
Lab Matters Joining forces to advance training in biomedical research and therapy
2019
lab-matters
Lab Matters On January 1 2019, Edith Heard takes up the position of EMBL’s Director General
2019
lab-matters
Science Scientists build self-organising features into robot swarms to study shape formation
2018
science
Lab Matters EMBL’s Design Team Lead on translating scientific discoveries into visual designs
2018
lab-matters
Science EMBL researchers have found a way to stop itch with light in mice
2018
science
Events What genetics can tell us about the structure of ancient human populations
2018
events
Science Cancer researchers have developed a computer model to predict the course of disease for prostate cancer
2018
science
Lab Matters EMBL’s GeneCore steps up to discover the facts and settle disputes
2018
lab-matters
Science Researchers develop new method to analyse the entire protein-RNA network of the cell
2018
science
Lab Matters EMBL partners with the Hungarian Centre of Excellence for Molecular Medicine
2018
lab-matters
Science EMBL-EBI industry case study: Biocatalysts
2018
science
Lab Matters What does it take to create a vaccine or improve cancer therapies?
2018
lab-matters
Events EMBL postdocs discover industry-led research opportunities at the Corporate Summer School
2018
events
Events The EMBL Teens reporters discover the European Researchers’ Night
2018
events
Science New algorithm will enhance understanding of relationship between genotype and environmental factors
2018
science
Lab Matters Building bridges between scientists and software developers
2018
lab-matters
Events Nina Kathe, Winner of the EU Contest for Young Scientists visits EMBL
2018
events
Lab Matters The EMBL Archive is open for business!
2018
lab-matters
Science Scientists uncover effects of mutation that can cause autism and intellectual disability
2018
science
Lab Matters How EMBL scientists are using machine learning to advance biology
2018
lab-matters
Science The De Renzis group investigated invagination, the first step of organ development in embryos.
2018
science
Alumni Translating 2D hospital scans into 3D prints is informing patients and aiding surgeons
2018
alumni
Science Genomes of 66,000 UK species to be sequenced in global effort to sequence all known eukaryotic species
2018
science
Science EMBL scientists investigate the structure of a key protein involved in blood clotting
2018
science
Science The Hentze Lab enhanced a RNA-interactome capture technique to pave the way towards medical progress
2018
science
Science Speeding up time-resolved X-ray crystallography with EMBL beamline P14
2018
science
Science EMBL researchers discover that four organs in a marine worm’s head can sense different chemicals
2018
science
Lab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
lab-matters
Events EMBL Barcelona invites locals to celebrate its Inauguration Symposium
2018
events
Lab Matters Ioanna Ydraiou and Bernd Pulverer spoke about their view of challenges and opportunities of OA.
2018
lab-matters
Science New study reveals how to make therapeutic insulins more effective than they currently are
2018
science
Science ERC grantees Wolfgang Huber and Oliver Stegle share their vision for the next 10 years
2018
science
Lab Matters Researchers at EMBL Hamburg have released the next generation of their ARP/wARP software
2018
lab-matters
Events 17 young scientists experienced hands-on training at EMBL Hamburg.
2018
events
Science How embryonic stem cells develop into the germ line
2018
science
Science EMBL scientists gain mechanistic insights into how cellular signalling controls gene regulation
2018
science
Alumni Meet Wendy Bickmore, Director of the MRC Human Genetics Unit, who spoke at the EMBL in the UK event
2018
alumni
Alumni EMBL alumni Gareth Griffiths and Rein Aasland receive the 2018 “Volunteer of the Year” award
2018
alumni
Alumni Scientists in Finland met to share ideas and discover research opportunities
2018
alumni
Alumni EMBL alumni and researchers working throughout Spain met in Madrid
2018
alumni
Science Researchers from EMBL and Heidelberg University unveil the molecular mechanisms of ageing
2018
science
Events Meet the organisers of EMBO’s first course on molecular geobiology
2018
events
Lab Matters EMBL and Promega collaborate to train young scientists
2018
lab-matters
Science Retromer’s 3D structure improves understanding of cellular sorting and packaging
2018
science
Science X-ray experiments show that scaffolding protein PDZK1 has a L-shaped conformation
2018
science
Science Real-time tracking of proteins during mitosis is now possible using a 4D computer model
2018
science
Lab Matters ATTRACT initiative will fund 170 breakthrough detection and imaging ideas with market potential
2018
lab-matters
Science Complex metabolomics analyses in the cloud
2018
science
Science EMBL scientists discover how a component of the cohesin ring binds DNA
2018
science
Events Theoretical physicist Robbert Dijkgraaf discusses the importance of curiosity-based research
2018
events
Science Large-scale systematic analysis explores how inherited genome affects drug response of cancer cells
2018
science
Science New head of the Mesoscopic Imaging Facility at EMBL Barcelona will help scientists visualise nature
2018
science
Lab Matters The ATTRACT initiative, of which EMBL is a partner, has launched an open call for seed funding
2018
lab-matters
Events The EMBL community, past and present, gather for special events around Lab Day 2018
2018
events
Events EMBL Rome opens its labs for students to get their first real taste of science
2018
events
Science An engineer’s approach to understanding morphogenesis
2018
science
Lab Matters Discover how EMBLers across all sites share their passion for science
2018
lab-matters
Science First global survey of soil genomics reveals a war between fungi and bacteria
2018
science
Science EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell
2018
science
Science The Protein Data Bank in Europe celebrates its schools art project with its largest exhibition yet
2018
science
Science Europe PMC adds preprints to its search
2018
science
Science Mammalian life begins differently than we thought
2018
science
Science Scientists show how bacteria and other microorganisms are passed on from mother to child
2018
science
Science Acute myloid leukaemia risk could be detected years before diagnosis
2018
science
Science New group leader at EMBL Barcelona creates artificial biological systems to study animal development
2018
science
Science EMBL scientists investigate how bacteria melt to study their reaction to drugs
2018
science
Science Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness
2018
science
Science EMBL scientists reveal NPC architecture of algae
2018
science
Alumni Alumni share how joining EMBL’s IT team was a career upgrade
2018
alumni
Science EMBL scientists investigate how influenza virus responds to new drug treatment
2018
science
Science EMBL researchers develop method that simplifies the isolation of DNA- and RNA- protein complexes
2018
science
Science Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device
2018
science
Events The programme promotes education, collaboration and cutting-edge research
2018
events
Science EMBL scientists extend Turing’s theory to help understand how biological patterns are created
2018
science
Science New computational method uses multi-omics analysis for personalised medicine
2018
science
Alumni More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan
2018
alumni
Science EMBL researchers guide the shape of cells and tissues with optogenetics
2018
science
Lab Matters Roche and EMBL join forces
2018
lab-matters
Lab Matters A history of EMBL in six objects from the EMBL Archive
2018
lab-matters
Science Which of our genes will be passed on to our children? Simone Köhler wants to find out
2018
science
Events EMBL and Pint of Science join forces to entertain and educate
2018
events
Science Of mice and gorillas: using mouse data for conservation
2018
science
Lab Matters Montenegro becomes EMBL’s 25th member state
2018
lab-matters
Science Scientists at EMBL Hamburg determine shapes of intermediate states in dynamic biological systems
2018
science
Science EMBL’s next Director General reflects on the questions that drive her research
2018
science
Alumni EMBL alumna Melina Schuh recognised for excellence in science
2018
alumni
Lab Matters EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing
2018
lab-matters
Science EMBL group leader Jan Korbel reflects on his scientific origins and current research
2018
science
Alumni Elisa Izaurralde, EMBL alumna, has passed away
2018
alumni
Lab Matters EMBL’s Director General has been elected to the National Academy of Sciences of the United States
2018
lab-matters
Science Researchers identify genes that can cause brain tumours in children and other cancers later in life
2018
science
Lab Matters EMBL alumna, Èlia Benito-Gutiérrez, on how her research and career evolved after searching the seas
2018
lab-matters
Alumni Mark Green, EMBL-EBI’s Head of Administration reflects on his time at the institute
2018
alumni
Science New platform transforms CRISPR gene editor into precision tool
2018
science
Lab Matters New partner strengthens drug discovery collaboration
2018
lab-matters
Science What worms can tell us about cancer
2018
science
Events On April 12, EMBL hosted 200 attendees at its Annual Reception in Heidelberg and highlighted its role as a training hub.
2018
events
Science EMBL scientists uncover large solubility and thermal stability changes of proteins during the cell cycle
2018
science
Science Discover how EMBL scientists are using GPU computing to push biology forward
2018
science
Science Scientists at EMBL Rome develop new method that uses light to manage neuropathic pain in mice
2018
science
Lab Matters Montenegro’s Minister of Science discusses the importance of international collaboration in research
2018
lab-matters
Science New Heidelberg group leader creates tools to help biologists work faster and better
2018
science
Science Dog and human gut microbiomes have more similar genes and responses to diet than previously thought
2018
science
Events Markus Ralser, upcoming EMBO workshop speaker, on how metabolism brought chemistry to life
2018
events
Science Open-source software allows standard microscopes to accurately image 3D structures
2018
science
Science EMBL scientists count and locate chromosomal proteins during cell duplication
2018
science
Science Launch of the first free global online catalogue of PDX models
2018
science
Science New EMBL-EBI Group Leader will make sense of bioimaging data
2018
science
Science For the first time, EMBL Rome researchers have captured microglia nibbling on brain synapses on film.
2018
science
Lab Matters Following the completion of the Human Genome Project in 2001, scientists and the media described the genome as “the book of life”, holding the answers to the way genes are linked to disease. Yet, seventeen years later, we are still deciphering how cells interpret this book. Since…
2018
lab-matters
Science What does a cell's location tell us?
2018
science
Science The new head of facility at EMBL Hamburg will help users solve protein puzzles
2018
science
Lab Matters EMBL Group Leader creates Ben Barres Prize to support talented young neuroscientists
2018
lab-matters
Science EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
2018
science
Science One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature
2018
science
Science EMBL scientists show how to grow a wide range of gut bacteria in the lab
2018
science
Science EMBL scientists unravel the molecular basis of a major antibiotic resistance transfer mechanism
2018
science
Science Scientists at EMBL and Cellzome develop technology to monitor the effects of drug treatments on protein degradation and synthesis
2018
science
Science EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories
2018
science
Events Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease
2018
events
Events EMBL experts outline the trends shaping scientific training in the coming years
2018
events
Lab Matters For Vasiliki Karyoti, troubleshooting and problem-solving take on a greater meaning at EMBL
2018
lab-matters
Events School students build fluorescence microscopes designed by members of the Prevedel group and ELLS
2018
events
Science EMBL scientists discover how two guidance cues work together when neurons project axons across the midline
2018
science
Lab Matters New EMBL spinoff company Velabs Therapeutics aims to speed up discovery of therapeutic antibodies
2018
lab-matters
Science Is depression in your genes?
2018
science
Lab Matters Maria Leptin reflects on how to create a research environment that serves the needs of the community
2018
lab-matters
Events EMBL and EMBO hosted the ERC's Scientific Council in Heidelberg 28 February to 2 March
2018
events
Alumni EMBL recognises the outstanding work of alumni with the John Kendrew and Lennart Philipson Awards
2018
alumni
Science Join us in our new editorial theme as we ask how everything began
2018
science
Science New technique offers insight into early cell life
2018
science
Lab Matters Discover the past lives and journeys that brought people to EMBL
2018
lab-matters
Science Access to state-of-the-art microscopes and outstanding expertise
2018
science
Science Researchers from Delft University and EMBL crack the mystery of condensin’s neat DNA loop extrusion
2018
science
Science EMBL scientists show that the rhythm between Wnt and Notch waves enables patterning in embryos.
2018
science
Science EMBL scientists discover how a molecule’s role changes from simple metabolite to instructive signal
2018
science
Lab Matters Joining forces for single-cell research
2018
lab-matters
Alumni “In testimony of my great thankfulness”
2018
alumni
Science New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies
2018
science
Events EMBL Barcelona organises first school activity to coincide with the International Day of Women in Science
2018
events
Science EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary cells
2018
science
Events EMBL experts outline the trends shaping scientific training in the coming years
2018
events
Science Network of genes linked to development of diabetes
2018
science
Science How Darwin’s work revealed the intimate relationship between orchids and insects
2018
science
Science EMBL’s new group leader studies how gene expression is controlled
2018
science
Events EMBL’s training programme launches its first e-learning courses: introductions to optogenetics and CLEM
2018
events
Lab Matters EMBL welcomes Slovakia as its 24th member state
2018
lab-matters
Events What opportunities can organoids bring to further the understanding of the human brain?
2018
events
Alumni Among refurbished labs, alumni relive memories and find traces of their time at EMBL
2018
alumni
Science EMBL scientists show that some promoters can act as enhancers and vice versa
2018
science
Lab Matters EMBL instrumentation teams adapting tech to run biological experiments on the synchrotron after its upgrade
2018
lab-matters
Science Nick Goldman of EMBL-EBI issued a challenge in 2015. In 2018, a winner emerged just in time.
2018
science
Science EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its work
2018
science
Science New EMBL group leader investigates the mystery of heritable gene silencing
2018
science
Science New group leader studies sea anemones to investigate why some animals regenerate better than others
2018
science
Science EMBL researchers solve a decades-long debate on a key process for brain and embryo-development
2018
science
Science EMBL scientists unveil how 3D chromatin structure affects RNA splicing
2017
science
Lab Matters Historian Soraya de Chadarevian explores how EMBL’s first Director General shaped molecular biology
2017
lab-matters
Science Molecule mapping method raises interest in forensics, agriculture and microbiome studies
2017
science
Lab Matters A look back at some of the most read stories on EMBL’s news website this year
2017
lab-matters
Science What are the strangest genomes in EMBL-EBI's Ensembl?
2017
science
Science ERC grantee Stephen Cusack shares his vision for the next ten years
2017
science
Events EMBL experts outline the trends shaping scientific training in the coming years
2017
events
Alumni EMBL physicist-turned-biologist alumni win 2017 Kendrew and Phillipson awards
2017
alumni
Science New research reveals that two different mechanisms are responsible for chromosome folding
2017
science
Alumni How a research technician with a master’s degree contributed to Nobel Prize-winning work
2017
alumni
Science EMBL scientists superimpose structures of two-metal-ion enzymes and reveal new potential drug targets
2017
science
Science New research shows how pores form in the membrane that surrounds a cell’s nucleus
2017
science
Science High resolution 3D protein structures in a giffy with PDBe
2017
science
Lab Matters Curious about what goes on in EMBL’s Fly Room? Prepare to be a fly on the wall
2017
lab-matters
Lab Matters Takeda joins pioneering public-private drug discover collaboration Open Targets
2017
lab-matters
Science New group leader based in Grenoble aims to unveil the mechanisms of RNA editing
2017
science
Science New BioModels infrastructure supports significantly more model formats and offers improved search
2017
science
Events James Sharpe, Head of EMBL Barcelona, co-chairs the morphogenetic engineering-themed conference
2017
events
Science New method for 3D imaging microorganisms lends insight into the creatures that inhabit our oceans
2017
science
Lab Matters EMBL Director General elect, Edith Heard, awarded 2017’s Grand Prix Inserm for her work in epigenetics
2017
lab-matters
Lab Matters EMBLers across all sites share how their curiosity about the world shapes their everyday life
2017
lab-matters
Lab Matters Interview with EMBL’s Joint Heads of Government and EU Relations
2017
lab-matters
Lab Matters Takashi Hiiragi and Lars Steinmetz received Advanced Grants from the European Research Council (ERC)
2017
lab-matters
Science The Mahamid group studies meso-scale molecular assemblies in intact cells and model organisms at molecular resolution
2017
science
Lab Matters EMBL releases recommendations for the 9th EU Framework Programme for Research and Innovation
2017
lab-matters
Alumni EMBL alumna Sigrid Reinsch trained as a cell biologist – now she helps run experiments in space
2017
alumni
Science Insights into the reproduction of Plasmodium parasites in mosquitoes reveal rapid and broad activity
2017
science
Events 20,000 visitors get sneak peek at giant particle accelerators at DESY DAY in Hamburg
2017
events
Alumni Former EMBL Director General Fotis Kafatos passes away
2017
alumni
Lab Matters Six curious questions and the EMBL community's answers. Check back each week for the next question
2017
lab-matters
Lab Matters EMBL and HeidelbergCement sign Memorandum of Understanding
2017
lab-matters
Alumni Jacques Dubochet, Nobel laureate and former EMBL group leader, reflects on a key aha moment
2017
alumni
Science EMBL researchers create highest resolution 3D model of important structure within Ebola virus
2017
science
Science Inside the Centre for Structural Systems Biology
2017
science
Science A summary of recent research highlights from EMBL
2017
science
Lab Matters EMBL and the European synchrotron ESRF extend their Joint Structural Biology Group
2017
lab-matters
Science As a new cryo-EM facility is inaugurated, EMBL’s Michael Hons describes his role in the project
2017
science
Science How open data is changing our pursuit of discovery
2017
science
Lab Matters Aid for Labs is an EMBL-based charity aiming to provide scientific equipment to researchers in need
2017
lab-matters
Science A talent for organisation has taken EMBL’s Steffi Kandels-Lewis across the globe
2017
science
Science Five things researchers have learned from bizarre fruit flies
2017
science
Science Find out how curiosity is driving some of the work we do here at EMBL
2017
science
Events Meet Ig Nobel emcee Marc Abrahams, an EMBL Science and Society speaker in December
2017
events
Events Interview with Rolf-Dieter Heuer, guest speaker at EMBL's 2017 Annual Reception
2017
events
Alumni Working on scientific instruments has taken EMBL alumnus Simon Sheldon to the ends of the Earth
2017
alumni
Alumni Alumnus Michael Parker talks about his career, research highlights and how EMBL has played a role
2017
alumni
Events Women from academia, industry and politics met at EMBL to fuel career growth and opportunities
2017
events
Science EMBL researchers and collaborators unravel how chromosomes form
2017
science
Science EMBL alumnus recognised for cryo-electron microscopy work
2017
science
Lab Matters How Australia’s associate membership of EMBL empowers scientists and drives collaboration
2017
lab-matters
Lab Matters Bernt Eric Uhlin, Director of MIMS, will replace Kjetil Taskén, Director of NCMM
2017
lab-matters
Science EMBL’s new group leader based in Hamburg aims to create models of infection cycles
2017
science
Lab Matters EMBL’s annual reception took place on 18 September, with more than 150 attendees
2017
lab-matters
Events EMBL-EBI and collaborators engage schools in a large-scale genome decoding project
2017
events
Science Q&A with EMBL-EBI's Head of Chemical Biology data services
2017
science
Science How microbes can create niches for each other
2017
science
Events International experts gather at EMBL-EBI to reflect on the future of bioinformatics training
2017
events
Science New study by Paola Kuri and Maria Leptin shows how inflammation happens in zebrafish in real time
2017
science
Events How the work of the Courses and Conferences team has changed over the years
2017
events
Lab Matters EMBL researchers separated facts from fiction at a Friends of EMBL Science Movie Night
2017
lab-matters
Science Newly opened European X-Ray Free-Electron Laser celebrates start of user operations
2017
science
Lab Matters German state and federal governments agree funding for microscopy centre at EMBL Heidelberg
2017
lab-matters
Science How patient-derived computational models can help researchers understand cancer
2017
science
Events Lars Steinmetz. Director of the Life Science Alliance, reflects on the EMBL|Stanford initiative
2017
events
Lab Matters Biologists Sydney Brenner and Richard J. Roberts addressed the importance of scientific archives
2017
lab-matters
Alumni EMBL alumni met in Oxford for an afternoon of science talks and networking
2017
alumni
Science Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development
2017
science
Science A new group at EMBL-EBI aims to decipher cell signalling networks
2017
science
Science The Iqbal research group hopes to build a 'Google of bacteria' to help better interpret the genome
2017
science
Lab Matters School student Andrea Totaro and EMBL group leader Christophe Lancrin reflect
2017
lab-matters
Lab Matters NEB joins EMBL’s corporate partnership programme
2017
lab-matters
Lab Matters EMBL-EBI supports bioinformatics training and capacity in Latin America
2017
lab-matters
Science Genetic data from a major cohort now distributed via EMBL-EBI
2017
science
Lab Matters EMBL’s cycling team complete epic journey to raise money for Heidelberg’s children’s hospital
2017
lab-matters
Lab Matters EMBL’s unit in Italy changes name to better reflect new research focuses and highlight its location
2017
lab-matters
Science EMBL’s Iain Mattaj, the new Chair of EIROforum, on EIROforum’s role
2017
science
Lab Matters On 29 June, at a ceremony in front of 700 guests, the Centre for Structural Systems Biology (CSSB) in Hamburg, was officially opened. At the event on the Deutsches Elektronen-Synchrotron (DESY) Campus in Hamburg, Helmut Dosch, Chairman of the DESY Board of Directors, presented Head of EMBL Hamburg…
2017
lab-matters
Events Tim Richmond looks back on the work that revealed the high-resolution structure of the nucleosome
2017
events
Events Celebrating 40 years since the first EMBO electron microscopy training course
2017
events
Events The 2018 EMBL course and conference sneak preview is now available!
2017
events
Lab Matters Edith Heard’s mandate scheduled to begin 1 January 2019
2017
lab-matters
Events Science and Society event answers controversial questions about gut microbes
2017
events
Science IMPC explains how much the sex of animals is misdirecting research results
2017
science
Science EMBL-EBI and IMPC characterised over 3000 mouse genes, revealing new gene associations with disease
2017
science
Events Exploring the potential of user experience for life sciences through industry workshops
2017
events
Science The Image Data Resource - prototype of the first open repository linking imaging and molecular data
2017
science
Science EMBL’s Cornelius Gross wants to understand fear responses and the brain circuitry that governs them
2017
science
Science EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
2017
science
Science Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
2017
science
Lab Matters EMBL-EBI, the Broad and UCSC Genomics Institute to build Data Coordination Platform with CZI support
2017
lab-matters
Science EMBL’s Hiroki Asari investigates how our internal state can change the way our eyes work
2017
science
Science Meet the head of EMBL's new Barcelona site, James Sharpe
2017
science
Lab Matters Inventor of OPT will be the first Head of EMBL’s new Barcelona site
2017
lab-matters
Science An EMBL collaboration devises a new method that could speed up vaccine development for HIV
2017
science
Lab Matters People across EMBL’s sites reflect on the ways they perceive their world
2017
lab-matters
Science Hallmarks of residual breat cancer cells suggest new approaches for preventing relapse
2017
science
Science Introducing one of the largest collections of high-quality human induced pluripotent stem cells
2017
science
Alumni The life science community is deeply saddened by the loss of EMBL alumnus Riccardo Cortese
2017
alumni
Lab Matters Accelerating researchers’ access to next-generation light-sheet microscopy
2017
lab-matters
Science Meet Monterotondo’s new group leader for epigenetic reprogramming and inheritance, Jamie Hackett
2017
science
Science ERC grantee Maja Köhn shares her vision for the next ten years
2017
science
Lab Matters EMBL welcomes its 23rd member state, with a promising collaboration already in place
2017
lab-matters
Science EMBL researchers develop an optical method for measuring the release of insulin from single cells
2017
science
Science EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus
2017
science
Science EMBL-EBI researchers identify mouse epigenetic clock that could help scientists understand ageing
2017
science
Lab Matters EMBL alumnus Konrad Müller has sadly passed away
2017
lab-matters
Lab Matters Call for applications for school students to join ‘Summer in Science’ in Monterotondo
2017
lab-matters
Science EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
2017
science
Lab Matters Spanish government and EMBL sign agreement for new site
2017
lab-matters
Lab Matters EMBL Director-General, Iain Mattaj, reflects on the work done to establish a new site in Barcelona
2017
lab-matters
Lab Matters EMBL’s Monterotondo site strengthens links with the Italian scientific community
2017
lab-matters
Science Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
2017
science
Lab Matters Silke Schumacher explains how the new EMBL site in Barcelona came into being
2017
lab-matters
Events New Master's programme for research infrastructure managers – set to launch autumn 2017
2017
events
Science Researchers use single-cell sequencing to understand how cells age
2017
science
Lab Matters Anna Tramontano, bioinformatics pioneer and EMBL alumna, has passed away
2017
lab-matters
Lab Matters Janet Thornton reflects on the contributions of EMBL alumna Anna Tramontano
2017
lab-matters
Alumni The research community mourns the passing of Anna Tramontano
2017
alumni
Lab Matters Diversity, internationality and collaboration works, writes EMBL Director-General Iain Mattaj
2017
lab-matters
Lab Matters “Without John Kendrew there would have been no EMBL,” wrote Ken Holmes
2017
lab-matters
Science ERC grantee Edward Lemke shares his vision for the next ten years
2017
science
Lab Matters EMBL’s new Academic Coordinator and Dean of Graduate Studies Monika Lachner leads programmes that help young scientists to flourish
2017
lab-matters
Science ERC grantee Detlev Arendt shares his vision for the next ten years
2017
science
Science ERC grantee Eileen Furlong shares her vision for the next ten years
2017
science
Science Keeping bacterial chromosomes tangled could lead to new approaches to treatment
2017
science
Lab Matters Ottoline Leyser on the fallacy of failure and the road to self-determination
2017
lab-matters
Science Reconstructing T-cell development in high resolution
2017
science
Science EMBL researchers develop a computer model to explore the movement of nuclei in a multinuclear cell
2017
science
Alumni EMBL alumnus Joep Muijrers talks about making the transition from science into business
2017
alumni
Science Differentiated and undifferentiated cells get energy in different ways, sensor made at EMBL shows
2017
science
Alumni EMBL alumna Zehra Sayers key driver of the Middle East’s first synchrotron project
2017
alumni
Alumni EMBL alumna Nicola Mulder reflects on her pan-African bioinformatics project and its impact
2017
alumni
Alumni Flies can do a lot for science, inside and outside the lab. EMBL alumna Isabel Palacios explains how
2017
alumni
Lab Matters Sartorius and EMBL join forces to support advanced training and science education
2017
lab-matters
Lab Matters GSK and EMBL have signed an agreement to enhance understanding of disease and drug mechanisms
2017
lab-matters
Lab Matters Beamline BM14 in Grenoble shuts down, continues collaboration with India
2017
lab-matters
Science A new technique developed at EMBL reveals the way fats interact with other molecules in cells
2017
science
Science EMBL scientists discovered that common mutations can change the shape of gene promoters
2017
science
Lab Matters In this interview from the EMBL Archive, Sir John Kendrew reflects on his time leading 'the Lab'.
2017
lab-matters
Lab Matters Helke Hillebrand on leaving EMBL after 9 years as Academic Coordinator and Dean of Graduate Studies
2017
lab-matters
Science Healing and anxiety are influenced by the genetics of one’s social partners
2017
science
Science New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression
2017
science
Science New mechanism revealed
2017
science
Science EMBL scientists find out how the prefrontal cortex puts a break on instinctive behaviours
2017
science
Science Understanding how the flu virus steals host RNA offers hope of new drugs
2016
science
Science Inducible mechanism found by EMBL scientists links receptor degradation and replenishment
2016
science
Lab Matters Ewan Birney's nine "Structures of Christmas" celebrate 20 years of PDBe
2016
lab-matters
Lab Matters Iain Mattaj on failure, adventure, determination and the Scientific Method
2016
lab-matters
Lab Matters For the past two months EMBL Heidelberg has hosted around 60 first year PhD students from EMBL’s International PhD Programme (EIPP). From thousands of applicants, the students were selected from over 40 countries to work on their PhD research at one of EMBL’s five sites – Grenoble, Hamburg,…
2016
lab-matters
Science EMBL scientists use new techniques to describe the architecture of conical HIV capsids
2016
science
Lab Matters A new crystallography platform in Grenoble opens the door to new technological developments
2016
lab-matters
Science Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers
2016
science
Events The PEPC course celebrated its 10th anniversary in Hamburg from the 12 – 20 September this year
2016
events
Science Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division
2016
science
Science New method combines signalling pathway data resources to improve systems biology research
2016
science
Science How Christian Löw’s failed experiment led to an unexpected scientific journey
2016
science
Lab Matters EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more
2016
lab-matters
Lab Matters How a team of scientists and artists at EMBL transformed microscopy data into stunning 3D images
2016
lab-matters
Science Exploring what it would take to regrow a lost limb, and what we might learn along the way
2016
science
Alumni Ernst Stelzer earns 2016 Lennart Philipson award for advances in light sheet microscopy
2016
alumni
Alumni EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
2016
alumni
Science Parasite’s method of rewiring our immune response leads to novel tool for drug tests
2016
science
Lab Matters EMBL study finds that rearranging how DNA packs the nucleus can activate cancer genes
2016
lab-matters
Science BLUEPRINT: EMBL-EBI and the push to decipher the blood epigenome
2016
science
Events Check out the newly revealed programme for 2017
2016
events
Science Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA
2016
science
Science Open source bioinformatics method for finding metabolites makes experiments comparable across labs
2016
science
Lab Matters Upgraded server room is ready to take the heat at EMBL Grenoble
2016
lab-matters
Lab Matters Hope Jahren’s autobiography educates and delights
2016
lab-matters
Science Where design meets bioinformatics, new scientific perspectives abound.
2016
science
Science What happens when plant's leaf-placing feedback loop isn't quite right
2016
science
Science Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms
2016
science
Events Participants learn about EMBL’s ocean biodiversity research at the Fall Gala
2016
events
Science New platform useful for studies of protein binding, human tissue and more
2016
science
Lab Matters We catch up with neuroscientist Craig Stark, speaker at the EMBL/EMBO Science and Society Conference
2016
lab-matters
Lab Matters Global Alliance for Genomics and Health chose Birney to lead efforts to bring genomics to the clinic
2016
lab-matters
Science A rapid, versatile mechanism that modifies proteins is revealed to be crucial for the evolutionary process
2016
science
Lab Matters Rosemary Wilson talks about imposter syndrome and how to handle it
2016
lab-matters
Science EMBL scientists investigate how leaves grow flat to efficiently capture sunlight
2016
science
Events CamNTF hosts meetings around Cambridge, open to all scientists interested in new therapeutics
2016
events
Science IMPC study identifies 410 genes essential to life in the mouse, providing a window on human disease
2016
science
Lab Matters EMBL recently attended the Naturejobs Career Expo, advising scientists about their career options
2016
lab-matters
Events Eberhard Bengsch explains why EMBL’s events programme attracts him time and again
2016
events
Lab Matters CORBEL Open Call launches October 2016, for access to 15 facilities and 8 research infrastructures
2016
lab-matters
Events Take part in an EMBL conference or symposium for free as an EMBL events reporter
2016
events
Science Side-effects of leukaemia drug explained, reveal possibility of repurposing to treat other diseases
2016
science
Science New head of Proteomics Core Facility also runs stability proteomics lab
2016
science
Science Puzzle of nuclear pore formation in growing nuclei solved
2016
science
Alumni EMBL alumnus Angus Lamond is driving forward new ways to explore the proteome
2016
alumni
Alumni Past meets present as Library head Ioanna Ydraiou interviews EMBL’s first librarian
2016
alumni
Science EMBL researchers help to design a lead compound active against four different pathogens
2016
science
Lab Matters Stephen Cusack looks back on the early days of his collaboration with Anacor developing anti-infectives
2016
lab-matters
Lab Matters Andrés Palencia on the design of compounds that may help fight drug-resistant TB and more
2016
lab-matters
Lab Matters A new repository helps identify emerging trends in data-driven science.
2016
lab-matters
Lab Matters EMBL and the Hubrecht Institute signed a 5-year partnership agreement
2016
lab-matters
Science Collaborating to take crystallography into a new time dimension
2016
science
Science 3D printing, gaming, virtual reality and lenticular posters bring new perspectives to research
2016
science
Lab Matters Turning the spotlight on the diverse universe of EMBL’s 200-strong postdoc community
2016
lab-matters
Lab Matters Celebrating the rich history of scientific contributions in Malta, EMBL's newest member state
2016
lab-matters
Science Emmanuelle Charpentier sheds light on how CRISPR–Cas9 went from side project to global revolution
2016
science
Lab Matters Unexpected adventures at EMBL LearningLAB focused on biodiversity
2016
lab-matters
Alumni "If I have an aim, I’ll find a solution" – meet EMBL alumnus Jochen Wittbrodt
2016
alumni
Lab Matters Integration, collaboration and openness on agenda for Carlos Moedas, European Commissioner for Research
2016
lab-matters
Science EMBL and ESRF scientists and mechanics work together on upgrade for one of Europe’s big X-ray sources
2016
science
Events Alumnus and entrepreneur Marc Zabeau speaks at inaugural Life Science Funders and Foundations event
2016
events
Science 'The PDB plays a crucial role in structural biology research and development'
2016
science
Lab Matters Bruce Alberts on fixing the broken academic career pipeline
2016
lab-matters
Alumni Scientific community manager, alumnus Aidan Budd, connects people with shared interests, values, goals
2016
alumni
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2016
lab-matters
Science Team leader investigates how the gut microbiome could relate to human diseases
2016
science
Science Storage of pre-made nuclear pores allows for rapid cell division in fruit fly embryos
2016
science
Science Detailed structure paves the way for more effective cancer therapies
2016
science
Lab Matters German students visit EMBL-EBI on a tour to explore a new culture and different career paths
2016
lab-matters
Science Strength of contraction determines whether cells become embryo or placenta
2016
science
Science Molecular messengers synthesised to help study how cells respond to outside stimuli
2016
science
Science New technique reveals uncharted docking sites in RNA-binding proteins
2016
science
Alumni EMBL Alumni Association Board review progress and discuss new initiatives
2016
alumni
Science Study provides insights into workings of new HIV drugs and how virus becomes resistant
2016
science
Science Core Technologies in Life Sciences (CTLS) association will be key resource for facility professionals
2016
science
Science “Like getting hold of a microscope for the first time”
2016
science
Science Collaborations shorten distance between EMBL Heidelberg, Germany, and CEITEC in Brno, Czech Republic
2016
science
Lab Matters In a time of great uncertainty, key facts about EMBL's status, collaborations, funding and recruitment
2016
lab-matters
Science New group leader combines physics and biology to answer the 'hows' of cell movement
2016
science
Alumni 27 former Bork lab members joined Peer for a full-day get-together this summer
2016
alumni
Lab Matters The UK’s decision to leave the EU has no direct consequences for the UK’s membership of EMBL
2016
lab-matters
Science Studying at EMBL in Grenoble helps Japanese postdoc see her native country through different eyes
2016
science
Science How cells eliminate protein deposits that can lead to neurodegenerative disorders
2016
science
Science Establishing a programme of research, development and user services for time-resolved crystallography
2016
science
Events Meet the secret timekeepers of EMBL events: AV technicians Sean Nightingale and Jan Abda
2016
events
Lab Matters Grenoble-based Partnership for Structural Biology (PSB) renewed for five more years
2016
lab-matters
Alumni Marco Tripoldi and Valeria Carola join colleagues and peers at gathering of Italy-based alumni
2016
alumni
Alumni Abel Ureta-Vidal and Louise Modis join colleagues and peers at gathering of UK-based alumni
2016
alumni
Science What's a microbiome? How on Earth do they work?
2016
science
Science Dozens of postdocs boosted their careers with a voyage aboard the Tara Oceans research schooner
2016
science
Science New method enables scientists to use light to direct where cancer cells go
2016
science
Science From shared interests at a conference to a surprising discovery
2016
science
Events Upgrading your conference experience with the new EMBL Events app
2016
events
Science Unexpected results: structure of DAPK enzyme reveals dual-purpose loop
2016
science
Science A perfect match: behaviourist Takefumi Kikusui visits the Gross group to explore animal attraction
2016
science
Science Largest-ever study of breast cancer genomes reveals new genes and mutations
2016
science
Science Stool transplants: finding the right match important, EMBL study shows
2016
science
Science How EMBL scientists are discovering and understanding the waves and rhythms inside us
2016
science
Science Florent Cipriani talks about his passion for developing beamline instrumentation
2016
science
Science EMBL PhD project puts development in a new light
2016
science
Events Neuroscientist and comedian Sophie Scott explains the complexity and social importance of laughter
2016
events
Lab Matters Review of 'Life’s Blueprint: The Science and Art of Embryo Creation' by Benny Shilo
2016
lab-matters
Alumni EMBL's ninth administrative director Keith Williamson looks back at 14 years at the Laboratory
2016
alumni
Lab Matters Illustrator Edmond Baudoin donates an original artwork to the EMBL Archive
2016
lab-matters
Alumni EMBL rewards the special work of alumni through the John Kendrew and Lennart Philipson awards.
2016
alumni
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2016
lab-matters
Alumni Meet a driving force behind collaborations with the Slovak Republic, alumnus Jozef Ševčik
2016
alumni
Alumni Gareth Griffiths, new Chair of the Alumni Association, reveals his many perspectives of EMBL
2016
alumni
Science CrystalDirect, developed at EMBL, automates crystal preparation for X-ray analysis
2016
science
Science First detailed structural description of all the rings of nuclear pores
2016
science
Alumni Alumna Angela Relogio tells us about her passion for science, communication and mentoring
2016
alumni
Science Why does a cookie look different depending on how hungry you are? Neuroscientist Asari wants to find out
2016
science
Science Information on structure of molecule used for genome engineering yields increased efficiency
2016
science
Science Subtle genetic differences destine cells to placenta or animal, very early in embryo development
2016
science
Science How an EMBL team is making and sharing tools to explore tuberculosis protein structures
2016
science
Science Commentary in Nature Methods introduces the EMPIAR resource and gives glimpse of future developments
2016
science
Science 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability
2016
science
Science New technique uses X-rays to find landmarks when combining fluorescence and electron microscopy
2016
science
Science Neural mechanisms in mouse brains indicate that we actively forget as we learn
2016
science
Science TraCeR: new method for studying T cells opens up opportunities to explore immune responses
2016
science
Lab Matters Award acknowledges leadership in gender equality on the Wellcome Genome Campus
2016
lab-matters
Events EMBL PlayLab now available at 22 conferences hosted in Heidelberg
2016
events
Science Structural insights into how cohesin keeps DNA together during the cell cycle
2016
science
Science First detailed atlas of start points for genes expression in malaria-causing parasite
2016
science
Lab Matters Iain Mattaj talks about the search for his successor
2016
lab-matters
Science “It’s a bit like drawing a picture of an intricate object just by looking at its shadow on the wall."
2016
science
Science How stem cells resist change
2016
science
Science What do cells in an embryo have in common with schools of fish, swarms of fireflies, and applauding audiences?
2016
science
Science How transcription factors interact to create a heart
2016
science
Lab Matters Independent analysis of EMBL-EBI underscores the value and impact of open data in the life sciences
2016
lab-matters
Science Plankton network linked to ocean's biological carbon pump revealed
2016
science
Lab Matters Pioneering target validation collaboration expands to accelerate drug discovery research.
2016
lab-matters
Science Protein screens developed at EMBL Hamburg now commercially available
2016
science
Alumni Former Head of EMBL Grenoble passed away on 21 January 2016 at the age of 89
2016
alumni
Lab Matters "We’re open! We’re open to working with everybody, we’re open to new things."
2016
lab-matters
Science Hamburg collaborators analyse protein crystals inside the cells that made them.
2016
science
Science Further insights into how viral enzymes degrade the cell walls of Clostridia bacteria.
2016
science
Events Scientist and showman: PhD student Vasily Sysoev shares his passion for outreach.
2016
events
Science New method is first to enable parallel profiling of the transcriptome and epigenome of a single cell.
2016
science
Science From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.
2015
science
Events With 28 conferences and 57 courses, 2016 will be EMBL’s most eventful year to date.
2015
events
Events Find out what’s in store at the 2016 Core Technologies for the Life Sciences meeting.
2015
events
Events GOBLET initiative supports pan-African bioinformatics trainers in Cape Town.
2015
events
Events Designer Aditya Kusuma Jati reveals what makes a good event poster.
2015
events
Science New microscope can record the first days of a mouse embryo’s life
2015
science
Science Making it easier to visualise, understand and predict how proteins combine to drive biological processes.
2015
science
Events Two PhD students sink their teeth into the science and speculations of Jurassic Park.
2015
events
Lab Matters Identifying evidence-based relationships between drug targets and diseases.
2015
lab-matters
Science Commonly used diabetes drug metformin impacts gut bacteria more than disease itself
2015
science
Lab Matters The new Toolkit for Trainers, an online resource hosted at EMBL-EBI, helps biomedical science trainers create and explore new ways of teaching.
2015
lab-matters
Lab Matters "There’s nothing nicer than seeing a user leave the facility happy"
2015
lab-matters
Events Connecting entrepreneurs and world leaders in genomics to address opportunities and challenges.
2015
events
Science CryoEM solves 3D atomic structure of largest and most elusive RNA polymerase.
2015
science
Lab Matters Compelling short stories that shine light on the life and work of EMBL staff.
2015
lab-matters
Lab Matters Roland Block, EMBL's Head of HR, on emphasising the ‘human’ in human resources.
2015
lab-matters
Science From jumping genes to organ transplants, the non-human features that make us human.
2015
science
Events What really sets humans apart? Forming societies, teaching and compassion, says Agustin Fuentes.
2015
events
Lab Matters Ewan Birney on the risks, rewards and realities of studying humans as a model species.
2015
lab-matters
Lab Matters Halldór Stefánsson on the long history of complex interactions between humans and animals.
2015
lab-matters
Lab Matters Giuseppe Testa reflects on the myriad intersections of our digital and biological lives.
2015
lab-matters
Events Highlights from the 'What makes us human?' symposium at EMBL Heidelberg.
2015
events
Lab Matters Postdoc Thibaut Brunet reviews two popular science books that explore the rise of Homo sapiens.
2015
lab-matters
Lab Matters What does a physicist do in a biology lab?
2015
lab-matters
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Lab Matters Sybrand van der Zwaag gives his five top tips for young researchers thinking about their next move.
2015
lab-matters
Events A snapshot of the many activities and events that took place in the world of EMBL this Autumn.
2015
events
Events Energy, enthusiasm and endurance on tap as thousands attend 12-hour Hamburg Night of Science.
2015
events
Science Using lasers to shed light on how tissues get into shape
2015
science
Events From paper microscopes to zebrafish embryos, EMBL Science Days stand had something for everyone.
2015
events
Events Annual EMBL-EBI Open Day showcases bioinformatics services, training and career opportunities.
2015
events
Science Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
science
Alumni Behind the scenes of the EMBL alumni chapter meeting in Zürich, Switzerland.
2015
alumni
Events Science met business and strangers became friends at the first Friends of EMBL Ladies Night.
2015
events
Science Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight
2015
science
Science Findings help demonstrate the evolutionary basis for allergy.
2015
science
Science Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.
2015
science
Lab Matters Hamburg researchers have a ball creating game to explain transporter protein mechanism.
2015
lab-matters
Alumni Behind the scenes of the EMBL-VIB alumni Benelux meeting.
2015
alumni
Science Evaluation of MinION™ sequencer finds performance and reliability consistently good.
2015
science
Science Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
2015
science
Lab Matters A microscopy technique is poised to shine new light on biological questions: as sheets of light can scan everything from developing embryos to single cells or functioning brains, a technique called light-sheet microscopy is gaining traction. It enables scientists to observe living cells in three…
2015
lab-matters
Science Spaghetti-like proteins are surprisingly effective 'keys'
2015
science
Lab Matters Amidst the excitement of Nobel Week, behind the scenes of the annual Lindau Nobel Laureate Meetings.
2015
lab-matters
Science 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation
2015
science
Science From the role of diatoms to how life evolved - scientists' pressing questions about life in the sea.
2015
science
Events Long-time events pro Antje Seeck gives us her take on how to organise a successful conference.
2015
events
Science Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.
2015
science
Lab Matters Sveiki Lietuva! Lithuania becomes EMBL’s fourth prospect member state.
2015
lab-matters
Events EMBL-Wellcome Genome Campus events collaboration showcases open, application-based science.
2015
events
Lab Matters Gold medal celebrates Eric Karsenti’s exceptional career and outstanding contributions to biology.
2015
lab-matters
Lab Matters Renewals and reunions: EMBL’s Nordic partners look to the future.
2015
lab-matters
Events Insights from organisers of upcoming EMBO|EMBL Aquatic Microeukaryotes symposium.
2015
events
Events Highlights from EMBL-EBI’s Training Programme: Open Day, revamped webpages, free webinar series.
2015
events
Science A nuclear pore riddle: how can you use the same number of pieces to form two rings that fit inside each other?
2015
science
Science MASSIF-1 processes its 10,000th crystal, less than one year after the beamline became operational.
2015
science
Science Multifaceted approach reveals how brain and liver age, helps explain why ageing brain loses plasticity.
2015
science
Lab Matters Introducing the Small Angle Scattering Biological Data Bank, developed at EMBL Hamburg.
2015
lab-matters
Events Tara Oceans research vessel welcomes aboard scientists, policymakers and funders.
2015
events
Alumni Ephrussi group alumni reunite in Heidelberg for a surprise birthday celebration.
2015
alumni
Alumni Alumni Rune Linding and Guillermo Montoya join colleagues and peers at the first Danish chapter meeting.
2015
alumni
Science New computational method to study biological signalling networks in healthy and cancer cells.
2015
science
Events Insights from the evangelical Vint Cerf, a “founding father of the Internet”, during a visit to EMBL.
2015
events
Lab Matters “A structure alone is not so interesting, you need the biology too,” says new NMR-focused group leader
2015
lab-matters
Alumni Genevieve Almouzni and Nicolas Le Novère share their insights at alumni chapter meeting hosted in the UK.
2015
alumni
Lab Matters New group explores why patients with same cancer exhibit unique constellations of genetic mutations.
2015
lab-matters
Events "It's like living a review!" Participants of recent super-resolution microscopy course share their highlights
2015
events
Lab Matters Maja Köhn’s lab is ideal to learn what life is like working at the interface of disciplines.
2015
lab-matters
Alumni EMBL rewards the special work of alumni through the John Kendrew and Lennart Philipson awards.
2015
alumni
Alumni Andrew Miller, first head of EMBL Grenoble, reflects on four decades at the Outstation.
2015
alumni
Lab Matters Janet Thornton reflects on her time as Director of one of Europe’s fastest growing research institutes.
2015
lab-matters
Alumni EMBL Alumni Association board meets for the last time in their current constellation.
2015
alumni
Alumni Results are in for the EMBL Alumni Association board election – the board takes up office in 2016.
2015
alumni
Science Theodore Alexandrov is using mathematics to analyse the countless molecules produced by our cells.
2015
science
Events Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.
2015
events
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Alumni Behind the scenes of start-up Miroculus, developing a non-invasive test for early-stage disease.
2015
alumni
Science A journalist who spent six weeks aboard Tara reflects on the expedition’s extraordinary outcomes.
2015
science
Lab Matters What’s on your Summer reading list? Here are some favourites of staff in the Lab.
2015
lab-matters
Alumni Alumnus Luis Bejarano asked Spanish students to stick out their tongues to analyse their microbiome.
2015
alumni
Events A contagious cancer threatens the Tasmanian devil – extract from Science in School journal.
2015
events
Alumni Alumni Reuben Leberman, Jeremy Smith, Elena Seiradake, and Winfried Weissenhorn share their stories.
2015
alumni
Lab Matters Maria Kamber, who heads the mouse facility, ensures “dignity, compassion and respect” for her charges.
2015
lab-matters
Science EMBL scientists map ‘switches’ for distant control of gene expression.
2015
science
Science Collaboration between scientists reveals collaboration between lipids.
2015
science
Lab Matters EMBL Core Facilities collaborate with French research programme Signalife to revive training visit.
2015
lab-matters
Events Leading scientists will gather in Heidelberg this November to discuss the potential of personalised health.
2015
events
Science Crowd sourcing initiative to predict effects of toxic compounds: results of 2013 DREAM Challenge.
2015
science
Science A mathematician who got ‘sucked in’ to biological problems, meet new team leader Theodore Alexandrov.
2015
science
Science Multidisciplinary research provides clues to new treatments for deadly form of leukaemia in children
2015
science
Science How T-cells are trained on what not to kill
2015
science
Lab Matters Molecular Medicine Partnership Unit (MMPU) with the University of Heidelberg, renewed until 2025.
2015
lab-matters
Lab Matters Alumnus Damian Brunner revisits EMBL in a very special capacity, as Swiss delegate on EMBL’s Council.
2015
lab-matters
Events Web of lies? Science Movie Night reveals science behind the most famous spider bite in film history.
2015
events
Science Iron regulatory proteins play important role in combatting infection, protecting against Salmonella.
2015
science
Science 3D structure of Oskar protein gives first molecular insight into how it functions.
2015
science
Lab Matters EI3POD: flagship interdisciplinary postdoc programme opens its doors to academia and industry.
2015
lab-matters
Science 3D imaging unravels COPI coat of cells' transport vesicles.
2015
science
Science Jan Korbel and colleagues publish commentary on risks and rewards of genome cloud computing.
2015
science
Science European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.
2015
science
Lab Matters “Interactions: that’s what I like the most in biology” – meet Lukáš Janošík, EUCYS 2014 prize winner.
2015
lab-matters
Lab Matters Database administrator's photo essay reflects internationality and personality of the Genome Campus.
2015
lab-matters
Lab Matters Academic community clouds take cancer research towards a brighter future.
2015
lab-matters
Events Industrial partners and BioStruct-X facility members gather for Workshop at EMBL Hamburg.
2015
events
Lab Matters Staff gather to celebrate Janet Thorton's 14 years as Director of EMBL-EBI.
2015
lab-matters
Events EMBL-EBI organises an evening of talks and discussion about the global spread of infectious disease.
2015
events
Science Behaviour of clathrin proteins, crucial for endocytosis, is clarified using new imaging techniques.
2015
science
Lab Matters Sarah Teichmann recognised for her contributions to science with the EMBO Gold Award 2015.
2015
lab-matters
Science A puzzling peculiarity resolved by Hamburg’s Sample Preparation and Characterisation facility.
2015
science
Events Staff, alumni, partners and more meet at EMBL Grenoble to celebrate Outstation's 40th anniversary.
2015
events
Science Researchers at EMBL-EBI speed up complex GWAS analyses with new method and algorithm.
2015
science
Lab Matters EMBL’s new open access policy aims to make EMBL research widely and freely accessible.
2015
lab-matters
Science Cells 'dance' as they draw together during early embryo development.
2015
science
Lab Matters CERN openlab enters a new phase, expanding to include EMBL-EBI and other public research organisations.
2015
lab-matters
Science Decaying RNA molecules tell a story that could add more chapters to the study of ribosomes.
2015
science
Lab Matters Jenny Cham blogs about how ORCID helps distinguish her from all the other Jenny Chams in the world.
2015
lab-matters
Lab Matters HMMER – a fast, sensitive search tool – helps find sequence relationships deep in evolutionary time.
2015
lab-matters
Lab Matters ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.
2015
lab-matters
Science Tara Oceans results reveal climate change insights, and a treasure trove of novel species and genes.
2015
science
Science Detailed structural study shows distantly related viruses share a common machinery for replication.
2015
science
Science EMBL scientists demonstrate that spatial constraints are a key factor in determining nucleus size.
2015
science
Science New research shows that some proteins domains can function even with big parts missing.
2015
science
Science Not all embryonic macrophages are the same, and only some are destined to become microglia.
2015
science
Science Unveiling the shape of... the 'molecular bin man' – cryoEM helps reveals p62 polymer in 3D.
2015
science
Science Stanford University biophysicist KC Huang on his collaboration with the Typas group in Heidelberg.
2015
science
Lab Matters Stephen Cusack, head of EMBL Grenoble, among 47 new Royal Society fellows.
2015
lab-matters
Lab Matters In their quest to make structural biology more accessible, PDBe launches a new website.
2015
lab-matters
Science Cooperate or compete? Microbes show us that getting along is the better choice for communities.
2015
science
Alumni Get ready to vote for your EMBL Alumni Association board.
2015
alumni
Lab Matters EMBL’s new Archivist will help chronicle the twists and turns, ups and downs of life at the Lab.
2015
lab-matters
Alumni Career insights from Riccardo Cortese, whose start-up is developing an Ebola vaccine candidate.
2015
alumni
Alumni Alumni in senior positions in industry share career challenges, highlights and EMBL’s continuing role.
2015
alumni
Lab Matters Q&A: Which analogy best describes your research?
2015
lab-matters
Events Ben Lillie takes us on a journey through the art and craft of personal narrative.
2015
events
Lab Matters Karin Sasaki is helping bridge the gap between quantitative and life science at EMBL.
2015
lab-matters
Science Radiocarbon studies are helping researchers shine light on how neurons stay stable yet adaptable.
2015
science
Science Ground-breaking microscopy technique gives unprecedented insight into endocytosis.
2015
science
Alumni Exploring the science and magic of Lil Bub – alumna launches project to sequence the ‘Lilbubome’.
2015
alumni
Science New single-cell genomics techniques bring ‘omics to evolution and development research.
2015
science
Lab Matters Major EU funding for CORBEL, facilitating access to data and biological imaging facilities.
2015
lab-matters
Lab Matters GWAS Catalog, originally developed by the NHGRI in the US, moves to EMBL-EBI.
2015
lab-matters
Science Coin toss inspires CorMap: a new statistical test that sidesteps need for error estimation.
2015
science
Science Go Team Genome! New method reveals genetic teamwork in drosophila genome.
2015
science
Lab Matters Klaus Tschira, a tireless supporter of science, education and talent, died 31 March 2015.
2015
lab-matters
Events EMBL’s corporate partners zoom in on big data and bioimaging.
2015
events
Science New fully automated technique enables scientists to chart complex protein networks in living cells.
2015
science
Lab Matters Rolf Apweiler and Ewan Birney appointed Joint Directors of EMBL-EBI, as Janet Thornton steps down.
2015
lab-matters
Lab Matters A quick round-up of the latest EMBL-EBI service releases.
2015
lab-matters
Lab Matters Wellcome Genome Campus gives first Best Practice Award for Supporting Women in Science.
2015
lab-matters
Alumni EMBL Grenoble celebrates 40 years with a symposium for staff, alumni and facility users on 4–5 June.
2015
alumni
Science Combining three different kinds of microscopy to determine how molecules move during endocytosis.
2015
science
Lab Matters Building and visualising protein-interaction networks is easier and more accurate thanks to IntAct.
2015
lab-matters
Lab Matters Jeffrey Barrett appointed Director of CTTV, the GSK, EMBL-EBI and Sanger Institute partnership.
2015
lab-matters
Science How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test
2015
science
Science Hamburg-led tuberculosis study demonstrates the power of collaboration.
2015
science
Events First LearningLAB of 2015 makes science of protein structure crystal clear for 22 teachers.
2015
events
Events EMBL Insight Lecture – Why do we do what we do? – now available to view online.
2015
events
Science Tried and tested do's and don'ts of crowdsource writing.
2015
science
Science New way mice starve pathogens raises alternative approach to treatments for anaemia of chronic disease
2015
science
Science New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.
2015
science
Science How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
science
Lab Matters A blog extract by Ewan Birney reflects on the challenges of moving a massive data-centre.
2015
lab-matters
Science New Bar-ChIP method makes it easier to search for epigenetic marks in many samples at once
2015
science
Science First experimental proof that a key cellular machine forms by uniting pre-assembled modules.
2015
science
Lab Matters Find answers to 40 of your questions about life, the Lab and everything!
2015
lab-matters
Alumni Films by alumnus’ lab shortlisted for 2014 Visualisation Challenge, 'The Vizzies'.
2015
alumni
Alumni How the Rosetta Mission’s comet landing led to unexpected destinations for alumna Karin Ranero,
2015
alumni
Science A brief history of microscopes, from van Leeuwenhoek to Betzig, Hell and Moerner.
2015
science
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Science As EMBL Hamburg celebrates 40 years, we explore the past, present and future of crystallography.
2015
science
Lab Matters Which tales have illuminated something important to you? Staff from the Lab provide their favourite.
2015
lab-matters
Lab Matters Meet Dean of Graduate Studies, Helke Hillebrand.
2015
lab-matters
Science From using light to control brain activity to illuminating fruit fly development and mice’s sense of touch
2015
science
Alumni Ken Holmes, one of the visionaries behind EMBL and EMBL Hamburg, looks back to where it all began.
2015
alumni
Lab Matters PhD student Silvia Rohr on studying eyes – and talking about it for a general audience.
2015
lab-matters
Alumni Alumnus Stefan Hell on his 2014 Nobel Prize for Chemistry
2015
alumni
Lab Matters New project aims to speed up detection and response to disease outbreaks using genome technology.
2015
lab-matters
Science New statistical method for RNA-seq analysis creates order out of seeming chaos.
2015
science
Lab Matters New Christian Boulin Fellowship: 15 awards of up to €1500 for visitors to EMBL’s Core Facilities.
2015
lab-matters
Science New group leader Marco Marcia aims to broaden horizons while mapping molecules.
2015
science
Lab Matters EMBL-EBI supports relaunch of yourgenome.org, to bring genetics advances to a wider audience.
2015
lab-matters
Science Research led by Teichmann group identifies fundamental mechanism for controlling protein function.
2015
science
Alumni Showcasing EMBL at the Congress of the Hellenic Society of Biochemistry and Molecular Biology.
2014
alumni
Science How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.
2014
science
Alumni Announcing winners of the John Kendrew Young Scientist Award, and inaugural Lennart Philipson Award.
2014
alumni
Science Compound that can restore the function of poorly working mitochondria, with therapeutic potential.
2014
science
Lab Matters Third round of calls for joint research projects between EMBL and Luxembourg in 2015
2014
lab-matters
Events EMBL Hamburg celebrates four decades of vision, pioneering research and beamline services.
2014
events
Lab Matters The day EMBL Hamburg predocs and postdocs invited Nobel Prize Winner Ada Yonath to dinner.
2014
lab-matters
Science Unprecedented detail in images of mouse neurons thanks to new SNAP-tagging microscopy technique.
2014
science
Alumni Employee number 47 retires, leaving behind a legacy that intricately linked her life with EMBL.
2014
alumni
Science Genome-based insights into evolution of malaria-carrying Anopheles mosquitoes.
2014
science
Science In two months, 2.3 million diffraction images collected on new, fully automated ESRF/EMBL beamline.
2014
science
Science Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
science
Lab Matters Workshops, seminars and honorary lectures – strong start for EMBL’s newest associate member state.
2014
lab-matters
Events Life Science Nord event reveals how pharmaceutical companies use synchrotrons for their research.
2014
events
Events EMBL-EBI supports Big Biology Day, inspiring 500 youngsters with jelly-baby DNA and golf-tee viruses.
2014
events
Alumni Get a flavour of the 15th EMBL|EMBO Science and Society Conference from alumnus Freddy Frischknecht.
2014
alumni
Science First complete picture of flu virus polymerase. A story of two decades of blood, sweat and sneezes.
2014
science
Alumni Alumnus Jan Medenbach harnesses the shared experience of peers (and pioneers) at EMBL event.
2014
alumni
Events Which courses and conferences will you attend in 2015? EMBL’s annual event calendar: out now!
2014
events
Events Appetite to ZzZzZzZ… bite-sized highlights from this year’s Science and Society conference.
2014
events
Science The important thing is forming good biological questions, says new group leader in Genome Biology.
2014
science
Events Course attendees go hunting (protein) aliens in a quest for optimal SAXS data.
2014
events
Science Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg
2014
science
Events First series of training courses jointly organised by EMBL and Illumina is a resounding success.
2014
events
Alumni Alumna Anna Bartosik shares insights and hopes for EMBL's newest prospect member state, Poland.
2014
alumni
Lab Matters 'Big Data to Knowledge' project by UCLA, Scripps and EMBL-EBI to transform protein data to knowledge.
2014
lab-matters
Science EMPIAR lets researchers take a closer look at the images used to build 3D molecular structures.
2014
science
Events Open Day in Grenoble celebrates crystallography for the Fête de la Science.
2014
events
Events In a Statement of Intent signed this month, Poland becomes a prospect member state of EMBL, and the new partners agree to explore possibilities for long-term cooperation, with a view to the country becoming a full member state within three years. “Poland has a strong and active life science…
2014
events
Science Unprecedented detail on HIV structure continues virus’ string of surprises.
2014
science
Events How to make good quality samples for good quality structural biology experiments.
2014
events
Science New, open repository helps researchers share computational models of disease.
2014
science
Science Kidney cancer linked to exposure to aristolochic acid, an ingredient in some herbal remedies.
2014
science
Lab Matters How the author of a prize-winning project on bee travel ended up at a stem cells and cancer conference
2014
lab-matters
Science Like sports teams, cells can huddle to communicate in secret and organise group behaviour
2014
science
Science Growth factor IGF-1 boosts natural defence against type-1 diabetes and multiple sclerosis
2014
science
Science European Variation Archive makes it easier to explore detailed information about genetic variation.
2014
science
Lab Matters How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?
2014
lab-matters
Science How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.
2014
science
Lab Matters Music, bubbles and DNA: a collaborative project brings artist and scientist together
2014
lab-matters
Science From anemones to starfish, sea creatures are helping understand development, evolution and more.
2014
science
Science Flow cytometry: finding needles in haystacks
2014
science
Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees
2014
lab-matters
Lab Matters Drumming, drama, dancing and discovery in a diary of art and science event, Roche Continents.
2014
lab-matters
Alumni It’s question time for Director General Iain Mattaj in this extract from the alumni reunion magazine.
2014
alumni
Lab Matters Bibliophiles from the Lab pick out the stories that have inspired them at work and elsewhere.
2014
lab-matters
Events Charles Spence invites you to taste the difference.
2014
events
Events German Science Minister and other honoured guests celebrate 40 years of ‘Learning from life’.
2014
events
Alumni Alumnus Giovanni Frazzetto on what happens when art, literature, theatre, and science come together.
2014
alumni
Lab Matters PhD student Charles breeze found inspiration at this year's Lindau Nobel Laureate meeting.
2014
lab-matters
Alumni Alumni Association elections: board member nominations wanted!
2014
alumni
Alumni EMBL Alumna Frieda Glöckner looks back more than four decades to where it all began.
2014
alumni
Events Experts from multiple fields come together to understand how the instructions in genes are read
2014
events
Science From vitamin C to safe matches, a sample of notable scientists from our newest prospect member state.
2014
science
Lab Matters Pathfinding – poetic and practical – was a common theme in blogs from the EMBL network.
2014
lab-matters
Events Pooling programming and problem-solving expertise in bioinformatics at EMBL-EBI.
2014
events
Events The European Molecular Biology Laboratory (EMBL) welcomes Hungary as its newest prospect member state. In a Statement of Intent signed this month, Hungary and EMBL agree to explore possibilities for long-term cooperation, with a view to the country becoming a full member state within three years.…
2014
events
Science How plankton gets jet lagged: the same hormone governs our sleep patterns and a daily marine migration.
2014
science
Events An interview with keynote speaker Michael Rossmann.
2014
events
Alumni Stephen Fuller, from 1981–2000 an EMBL postdoc, group leader then Head of Unit, died on 25 August.
2014
alumni
Events EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2014
events
Science Evolutionary surprise: notochord likely evolved from muscle, earlier than assumed.
2014
science
Science Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
science
2014
events
Science Gibbon genome gives insights into evolution of this singing, swinging, tree-dwelling ape.
2014
science
Science RNAcentral is the first unified resource for all types of non-coding RNA data.
2014
science
Lab Matters Andrew D Robertson, scientific coordinator of EICAT between 2011–12, died on 14 August 2014.
2014
lab-matters
Lab Matters Tschira-Jugendakademie pupils get hands-on during day of DNA barcoding
2014
lab-matters
Events Research building for interdisciplinary Centre for Structural Systems Biology (CSSB) takes shape.
2014
events
Science Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
science
Lab Matters Nordic partners focus on "enhancing research enterprise", says Kjetil Taskén
2014
lab-matters
Events PhD Symposium poster reveals how a cell’s inner workings serve as both inspiration and toolkit.
2014
events
Science Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
2014
science
Lab Matters Artist Stephen Wright gifts artwork inspired by DNA storage research to EMBL-EBI.
2014
lab-matters
Events PhD students reap rewards and rave reviews as Summer School of Science organisers
2014
events
Lab Matters A quick round-up of the latest EMBL-EBI service releases
2014
lab-matters
Lab Matters Gyron Ltd awarded contract to supply EMBL-EBI's data centres over the next five years
2014
lab-matters
Science How a single molecule can attract and repel growing brain connections
2014
science
Science Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
science
Science A rare form of an iron overload disorder kills pancreatic function, Heidelberg scientists find
2014
science
Science How fruit flies beat the cold, plus the value of precisely controlled experiments and detailed analysis
2014
science
Science Edward Lemke edits special issue of ChemBioChem on boom of technology for genetic code expansion
2014
science
Events EMBL students successfully take science to the pub
2014
events
Alumni "Thank you, EMBL, for changing my life" – reunion celebrates great science and great scientists
2014
alumni
Lab Matters New genomics API allows researchers to share anonymised genetic data seamlessly across platforms.
2014
lab-matters
Alumni Celebrating 50 years of EMBO, 40 years of EMBL and the success of molecular biology in Austria
2014
alumni
Science Molecular switch enables viruses to destroy C.diff bacteria – potential alternative to antibiotics
2014
science
Science Marmoset genome provides insights into chimerism: data available in Ensembl genome explorer
2014
science
Science Cell biologists "underestimate the complexity" of protein interactions, says Toby Gibson.
2014
science
Lab Matters Have a pressing question? EMBL experts are standing by to answer! Submit yours today.
2014
lab-matters
Lab Matters Czech delegate Jana Bystřická represents EMBL's 21st member state at her first Council Meeting.
2014
lab-matters
Science Embed chemists in biology departments, asking their own biological questions, says Carsten Schultz
2014
science
Events Anniversary reflections on connections between scientific and political interests.
2014
events
Alumni EMBL-EBI’s anniversary celebration: blue skies thinking, Robin Ince and a biology-themed cake
2014
alumni
Alumni EMBL Monterotondo celebrates double anniversary with fun, fireworks, festa and familiar faces
2014
alumni
Science Surprising finding: enhancers find their targets long before activation in Drosophila embryos
2014
science
Lab Matters As the Lab turns 40, staff and alumni share 40 things that make EMBL, EMBL
2014
lab-matters
Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’
2014
lab-matters
Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees
2014
lab-matters
Alumni Scientist-turned-writer Lucas Brouwers follows his instincts to find interesting stories
2014
alumni
Science Surprising protein from a flu-like virus is 10 000th ESRF structure
2014
science
Lab Matters To photographer Horst Hamann, it's the people, not the science, that make EMBL unique
2014
lab-matters
Lab Matters Film enthusiasts from the Lab review their favourite science movies, one for each EMBL decade
2014
lab-matters
Science Focusing on basic research is crucial for the development of more advanced genetics techniques
2014
science
Lab Matters Christian Boulin, EMBL’s Director of Core Facilities and Services, died on 27 April 2014
2014
lab-matters
Lab Matters What might life alien life look like? Lewis Dartnell studies extreme bacteria to find out
2014
lab-matters
Lab Matters As the Lab turns 40, staff and alumni share 40 things that make EMBL, EMBL
2014
lab-matters
Alumni Two EMBL alumni, each developing community-led tools to support life science research
2014
alumni
Science New ways of handling and distributing data at PDBe to tackle ever larger and more complex proteins
2014
science
Lab Matters Busy times for EMBL keep Director of International Relations Silke Schumacher on the move
2014
lab-matters
Alumni New EMBL Archive will serve as a record of accomplishments, past, present and future
2014
alumni
Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead
2014
lab-matters
Lab Matters Which scientific breakthroughs would EMBL scientists most like to see in the next 40 years?
2014
lab-matters
Alumni Staff and alumni around the world get active in EMBL running shirts to celebrate our anniversary
2014
alumni
Lab Matters A new EMBL-EBI biomedical initiative works to determine the best target proteins for new drugs.
2014
lab-matters
Science Scientists determine the structure of auxin response factors: daisy-chains that regulate gene expression
2014
science
Science Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA
2014
science
Science Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
science
Events Teaming up in Ireland to address big challenges in biology
2014
events
Events Forty years after its foundation, EMBL announces its 21st member state: the Czech Republic. Building on a successful bilateral relationship, the Czech Republic’s membership grants Czech scientists access to EMBL’s state-of-the-art instruments, facilities and world-class training…
2014
events
Science Reference sheep genome, published by International Sheep Genomics Consortium, available in Ensembl
2014
science
Science A kaleidoscope of molecules is needed to clean up dead brain cells, and failure can have disastrous consequences
2014
science
Science How a DNA stretch influences face formation and contributes to common congenital malformations
2014
science
Science High-resolution structure reveals crucial interactions for HIV maturation
2014
science
Science DNA-coralling protein complex in an unexpected bind
2014
science
Science Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
science
Science The balance behind membrane changes that turn one cell into 6000 as a fruit fly embryo develops
2014
science
Science Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
science
Events At a signing ceremony today, Argentina joins the European Molecular Biology Laboratory (EMBL) as an associate member state. The move strengthens the ties between the European and Latin American life science communities. It grants Argentinian scientists access to EMBL’s world-class facilities and…
2014
events
Lab Matters A pioneering public-private research initiative between GSK, the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute is to harness the power of ‘big data’ and genome sequencing to improve the success rate for discovering new medicines. The new Centre for…
2014
lab-matters
Events The European Molecular Biology Laboratory (EMBL) welcomes the Slovak Republic as the first country to join its new Prospect Member scheme. In a Statement of Intent signed last month, the Slovak Republic and EMBL agree to explore the possibilities for long-term cooperation, with a view to the…
2014
events
Lab Matters Europe is uniting to make state-of-the-art imaging technologies accessible to biomedical researchers throughout the continent in a concerted manner. The European Molecular Biology Laboratory (EMBL) and seven countries (Belgium, Finland, Italy, Poland, Slovakia, the Netherlands, the United Kingdom)…
2014
lab-matters
Science In many people with autism and other neurodevelopmental disorders, different parts of the brain don’t talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about. In a study published online today…
2014
science
Science What do bullies and sex have in common? Based on work by scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, it seems that the same part of the brain reacts to both. In a study published today in Nature Neuroscience, the researchers found that – at least in…
2013
science
Science The molecular machine that makes essential components of ribosomes – the cell’s protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Centro de Investigaciones Biológicas in Madrid, Spain, have found.…
2013
science
Science An important step in building ribosomes – the cell’s protein factories – is like a strictly choreographed dance, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. To build these factories, other ‘machines’ inside the cell have to…
2013
science
Science Migrating cells, it seems, cover their tracks not for fear of being followed, but to keep moving forward. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now shown that cells in a zebrafish embryo determine which direction they move in by effectively…
2013
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis. Their work, published online today in Cell, also uncovers a…
2013
science
Science Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…
2013
science
Science How our body processes cholesterol has a well-known impact on our health, but it turns out that another ‘fat molecule’ – or lipid – may be at the heart of some diseases which were thought to involve cholesterol. A group of proteins linked to conditions such as metabolic syndrome and some…
2013
science
Science The process cells use to ‘swallow’ up nutrients, hormones and other signals from their environment – called endocytosis – can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study,…
2013
science
Science It’s a parent’s nightmare: opening a Lego set and being faced with 500 pieces, but no instructions on how to assemble them into the majestic castle shown on the box. Thanks to a new approach by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…
2013
science
Science Although we know the tool’s general purpose, it can sometimes be difficult to tell if a specific pair of precision tweezers belongs to a surgeon or a master jeweller. It is now easier to solve similar conundrums about a type of protein that allows cells to react to their environment, thanks to…
2013
science
Science Like musicians in an orchestra who have the same musical score but start and finish playing at different intervals, cells with the same genes start and finish transcribing them at different points in the genome. For the first time, researchers at EMBL have described the striking diversity of…
2013
science
Lab Matters Euro-BioImaging, the pan-European open access research infrastructure for biological and medical imaging technologies, invites leading European imaging facilities to submit proposals to participate. Applications to become a Euro-BioImaging node will be reviewed by a board of independent…
2013
lab-matters
Science HeLa cells are the world’s most commonly used human cell lines, and have served as a standard for understanding many fundamental biological processes. In a study published today in G3: Genes, Genomes and Genetics online, scientists at the European Molecular Biology Laboratory in…
2013
science
Lab Matters Today, the Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones: the renewal of the partnership agreement for an extended period of 10 years, and the expansion of the Nordic EMBL network with the official opening of the Danish Research Institute of Translational…
2013
lab-matters
Science During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and…
2013
science
Science Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease. Researchers from the European Molecular Biology Laboratory (EMBL) and the…
2013
science
Science While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany*, have…
2013
science
Science Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie…
2013
science
Science Scientists at the EMBL-European Bioinformatics Institute (EMBL-EBI) and the MRC Laboratory of Molecular Biology in the UK have discovered how our genome keeps the effects of mutations in check. The discovery, published in the journal Cell, will help in the study of diseases such as cancer and…
2013
science
Science Researchers at the EMBL-European Bioinformatics Institute (EMBL-EBI) have created a way to store data in the form of DNA – a material that lasts for tens of thousands of years. The new method, published today in the journal Nature, makes it possible to store at least 100 million hours of…
2013
science
Science This may look like yet another video of a dividing cell, but there’s a catch. You are looking at chromosomes (red) being pulled apart by the mitotic spindle (green), but it’s not a cell, because there’s no cell membrane. Like a child sucking an egg out of its shell, Ivo Telley from the…
2013
science
Science A research team of scientists from EMBL Grenoble and the IGBMC in Strasbourg, France, have, for the first time, described in molecular detail the architecture of the central scaffold of TFIID: the human protein complex essential for transcription from DNA to mRNA. The study, published today…
2013
science
Science Gene expression wave in the lower part of the future vertebrae column of a mammalian embryo. As the wave goes forward, new pre-vertebrae are formed and the future vertebrae column elongates. (Image and video credit: Nature) In a nutshell: The size of pre-vertebrae in a mammalian embryo is…
2012
science
Science In a nutshell : The gut metagenome is the collection of all the genomes of all the microbes in the human intestinal tract : it is specific to each human, like a second genetic signature At least in healthy humans, this personal metagenome is stable over time The gut metagenome is…
2012
science
Science In a nutshell: 1st map combining human genetic variation at different scales – from single letters to large chunks Based on genomes of 1092 healthy people from Europe, the Americas and East Asia Could help identify genetic causes of disease, rather than just links Data made freely available in…
2012
science
Science In a nutshell: Looping and unlooping DNA adjusts readout from gene and spread of regulation throughout the genome When a gene forms a loop, its output increases, as the transcription machinery that reads it is trapped into moving only along that gene When the gene loop is undone, transcription…
2012
science
Science In a nutshell: New method allows precise analysis of proteins released by cells over time (distinguishes them from proteins in the cells’ culture serum) Advantages: cells don’t have to be starved: avoids bias and allows more cell types to be studied; can follow fast reactions like immune…
2012
science
Science Today, an international team of researchers reveal that much of what has been called ‘junk DNA’ in the human genome is actually a massive control panel with millions of switches regulating the activity of our genes. Without these switches, genes would not work – and mutations in these regions…
2012
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have combined the power of two kinds of microscope to produce a 3-dimensional movie of how cells ‘swallow’ nutrients and other molecules by engulfing them. The study, published today in Cell, is the…
2012
science
Science Researchers at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have determined the detailed 3-dimensional structure of part of the flu virus’ RNA polymerase, an enzyme that is crucial for influenza virus replication. This important finding is published today in PLoS…
2012
science
Science What do you get when you dissect 10 000 fruit-fly larvae? A team of researchers led by the EMBL- European Bioinformatics Institute (EMBL-EBI) in the UK and the Max Planck Institute of Immunobiology and Epigenetics (MPI) in Germany has discovered a way in which cells can adjust the activity of many…
2012
science
Science Italy has pledged to participate in ELIXIR, a major undertaking to safeguard the results of life science research in Europe. With one of Europe’s larger economies now demonstrating its commitment to ELIXIR, this burgeoning research infrastructure is well placed to continue its excellent progress.…
2012
science
Science A traffic policeman standing at a busy intersection directing the flow of vehicles may be a rare sight these days, but a similar scene appears to still frequently play out in our cells. A protein called Lem4 directs a crucial step of cell division by preventing the progress of one molecule while…
2012
science
Science Savira pharmaceuticals GmbH, a spin-off of the European Molecular Biology Laboratory (EMBL) based in Vienna, Austria, has signed a collaboration and license agreement with Roche, thus further strengthening the links between fundamental research and major pharmaceutical development companies. This…
2012
science
Science As a retrovirus matures, the two parts of its shell protein (red and blue or yellow and blue) dramatically rearrange themselves, twisting and moving away from each other. (Credit: EMBL/T.Bharat) Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have for the…
2012
science
Science “This video shows a fruit fly embryo from when it was about two-and-a-half hours old until it walked away from the microscope as a larva, 20 hours later,” says Lars Hufnagel, from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. “It shows all the hallmarks of fruit fly…
2012
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have conducted the first comprehensive census of human cells’ export workers. In a study published online today in Nature Cell Biology, they found an unexpected variety of genes involved in transporting…
2012
science
Science In one of the most famous faux pas of exploration, Columbus set sail for India and instead ‘discovered’ America. Similarly, when scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, set out to find enzymes – the proteins that carry out chemical…
2012
science
Science Like emergency workers rushing to a disaster scene, cells called microglia speed to places where the brain has been injured, to contain the damage by ‘eating up’ any cellular debris and dead or dying neurons. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…
2012
science
Science Just as banks store away only the most valuable possessions in the most secure safes, cells prioritise which genes they guard most closely, researchers at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) have found. The study, published online today…
2012
science
Science Like any law-abiding train passenger, a molecule called oskar RNA carries a stamped ticket detailing its destination and form of transport, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. They show that for this molecule, moving in the…
2012
science
Science Today a consortium of leading IT providers and three of Europe’s biggest research centres (CERN, EMBL and ESA) announced a partnership to launch a European cloud computing platform. ‘Helix Nebula ‐ the Science Cloud’, will support the massive IT requirements of European…
2012
science
Science The bacterium Mycoplasma pneumoniae, which causes atypical pneumonia, is helping scientists uncover how cells make the most of limited resources. By measuring all the proteins this bacterium produces, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and…
2012
science
Science Breakthroughs in biomedical science are a step closer today, with the launch of a new distributed research infrastructure for the science of structural biology: Instruct. The launch of Instruct will give academic and commercial scientists across Europe access to a full portfolio of integrated…
2012
science
Science In fairy tales, magic rings endow their owners with special abilities: the ring makes the wearer invisible, fulfils his wishes, or otherwise helps the hero on the path to his destiny. Similarly, a ring-like structure found in a protein complex called ‘Elongator’ has led researchers at the…
2012
science
Science Myomesin stretching to 2.5 times its length. Credit: EMBL/Wilmanns. In this video, a protein called myomesin does its impression of Mr. Fantastic, the leader of the Fantastic Four of comic book fame, who performed incredible feats by stretching his body. Scientists at the European Molecular Biology…
2012
science
Science If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the…
2012
science
Science An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University…
2012
science
Science A team of geneticists and computational biologists at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), the Wellcome Trust Sanger Institute and Cancer Research UK reveal how an ancient mechanism is involved in gene control and continues to drive genome…
2012
science
Science As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…
2012
science
Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) and the Biotechnology and Biological Sciences Research Council (BBSRC) warmly welcome today’s announcement from the UK Government of a £75 million commitment from the Department for Business, Innovation…
2011
lab-matters
Science When a thief breaks into a bank vault, sensors are activated and the alarm is raised. Cells have their own early-warning system for intruders, and scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered how a particular protein sounds that alarm when it…
2011
science
Lab Matters Today marks an important step for ELIXIR, Europe’s emerging research infrastructure for life-science information, as five countries plus the European Molecular Biology Laboratory (EMBL) have signed a Memorandum of Understanding to catalyse the implementation and construction of ELIXIR. The…
2011
lab-matters
Science When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell’s interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. The unexpected degree of trial-and-error…
2011
science
Science Researchers can now watch molecules move in living cells, literally millisecond by millisecond, thanks to a new microscope developed by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Published online today in Nature Biotechnology, the new technique provides…
2011
science
Science Gardeners know that some trees require regular pruning: some of their branches have to be cut so that others can grow stronger. The same is true of the developing brain: cells called microglia prune the connections between neurons, shaping how the brain is wired, scientists at the European…
2011
science
Science A fungus that lives at extremely high temperatures could help understand structures within our own cells. Scientists at the European Molecular Biology Laboratory (EMBL) and Heidelberg University, both in Heidelberg, Germany, were the first to sequence and analyse the genome of a heat-loving fungus,…
2011
science
Lab Matters Lennart Philipson, who served as EMBL’s second Director General, has passed away. Lennart headed EMBL for over a decade between 1982-93, a crucial time for molecular biology when different scientific disciplines in the life sciences were becoming increasingly interlinked. He reorganised the…
2011
lab-matters
Science As any rock-climber knows, trailing a long length of rope behind you is not easy. A dangling length of rope is unwieldy and hard to manoeuvre, and can get tangled up or stuck on an outcropping. Cells face the same problem when dragging chromosomes apart during cell division. The chromosomes are…
2011
science
Science In the future, when you walk into a doctor’s surgery or hospital, you could be asked not just about your allergies and blood group, but also about your gut type. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and collaborators in the international MetaHIT…
2011
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT. It enables researchers to…
2011
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method which enables researchers to label any protein of their choice with any of a wide variety of previously available compounds, in living cells, by introducing a single reactive…
2011
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can…
2011
science
Lab Matters In a Memorandum of Understanding signed today, the European Commission (EC) and the European Molecular Biology Laboratory (EMBL) formalise their desire to maintain and further develop their cooperation. “I am delighted to sign the renewed and strengthened Memorandum of Understanding between the…
2011
lab-matters
Science In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The new findings…
2011
science
Lab Matters The Biotechnology and Biological Sciences Research Council (BBSRC) and the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) welcome news that funding has been earmarked from the UK’s Large Facilities Capital Fund for ELIXIR – the European Life-science…
2011
lab-matters
Science In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body’s stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit (MMPU), a collaboration between the European Molecular…
2011
science
Science A detailed analysis of data from 185 human genomes sequenced in the course of the 1000 Genomes Project, by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with researchers at the Wellcome Trust Sanger Institute in Cambridge, UK, as well as the…
2011
science
Science The sight of a researcher sitting at a microscope for hours, painstakingly searching for the right cells, may soon be a thing of the past, thanks to new software created by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Presented today in Nature Methods, the…
2011
science
Science Like an overprotective parent on the first day of school, a targeting factor sometimes needs a little push to let go of its cargo. Scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have visualised one such hand-over. They were the first to determine the structure…
2010
science
Science From microscopy to computer tomography (CT) scans, imaging plays an important role in biological and biomedical research, but obtaining high-quality images often requires advanced technology and expertise, and can be costly. Euro-BioImaging, a project which launches its preparatory phase today,…
2010
science
Science The cells in the different parts of this video are always the same (grey), but, like actors using make-up to highlight different facial features, they have fluorescent labels that mark different cellular components in different colours: blue shows the nucleus, yellow shows tubulin (a component of…
2010
science
Lab Matters At the Autumn 2010Council meeting of the EIROforum, a partnership of seven European intergovernmental research organisations with large research infrastructures, the Directors General unanimously accepted the European X-Ray Free-Electron Laser Facility (European XFEL), based in Hamburg, Germany, to…
2010
lab-matters
Science The 1000 Genomes Project, a major international collaboration to build a detailed map of human genetic variation, has completed its pilot phase. The results are now published in the journal Nature and freely available through the European Molecular Biology Laboratory’s European Bioinformatics…
2010
science
Science Our cerebral cortex, or pallium, is a big part of what makes us human: art, literature and science would not exist had this most fascinating part of our brain not emerged in some less intelligent ancestor in prehistoric times. But when did this occur and what were these ancestors? Unexpectedly,…
2010
science
Science Fear can make you run, it can make you fight, and it can glue you to the spot. Scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy and GlaxoSmithKline in Verona, Italy, have identified not only the part of the brain but the specific type of neurons that determine…
2010
science
Science During cell division, microtubules emanating from each of the spindle poles meet and overlap in the spindle’s midzone. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have uncovered the molecular mechanism that determines the extent of this overlap. In a…
2010
science
Science Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. In a study published today in Cell Metabolism, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg,…
2010
science
Science The scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, who ‘fathered’ the Digital Embryo have now given it wings, creating the Fly Digital Embryo. In work published today in Nature Methods, they were able to capture fruit fly development on film, and were the…
2010
science
Science Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too.…
2010
science
Science Red blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second – even more in response to challenges like severe blood loss. In a study published today…
2010
science
Science During embryonic development, proteins called Polycomb group complexes turn genes off when and where their activity must not be present, preventing specialised tissues and organs from forming in the wrong places. They also play an important role in processes like stem cell differentiation and…
2010
science
Science Just like members of an orchestra are active at different times although playing the same piece of music, every cell in our body contains the same genetic sequence but expresses this differently to give rise to cells and tissues with specialised properties. By integrating gene expression data from…
2010
science
Science Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…
2010
science
Science Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Yale and Stanford Universities in the USA, have found that we differ from each other mainly because…
2010
science
Lab Matters Today, the Nordic EMBL Partnership for Molecular Medicine officially inaugurates the Institute for Molecular Medicine Finland (FIMM) in Helsinki. Together with the Centre for Molecular Medicine Norway (NCMM, University of Oslo) and the Laboratory for Molecular Infection Medicine Sweden (MIMS, Umeå…
2010
lab-matters
Lab Matters Today, the German Minister for Education and Research, Annette Schavan, officially opens the new training and conference centre for the life sciences on the campus of the European Molecular Biology Laboratory (EMBL) in Heidelberg. “This new centre in Heidelberg will form a central European…
2010
lab-matters
Science The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…
2010
science
Science The last ancestor we shared with worms, which roamed the seas around 600 million years ago, may already have had a sophisticated brain that released hormones into the blood and was connected to various sensory organs. The evidence comes not from a newly found fossil but from the study of microRNAs…
2010
science
Science Cells rely on a range of signalling systems to communicate with each other and to control their own internal workings. Scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have now found a way to hack into a vital communications system, raising the possibility of…
2010
science
Science Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…
2010
science
Science ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new…
2010
science
Science Is it a boy or a girl? Expecting parents may be accustomed to this question, but contrary to what they may think, the answer doesn’t depend solely on their child’s sex chromosomes. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and the Medical Research…
2009
science
Science Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the recovery from heart attacks. In a study published today in Circulation Research, scientists at the European Molecular Biology Laboratory (EMBL)…
2009
science
Science What are the bare essentials of life, the indispensable ingredients required to produce a cell that can survive on its own? Can we describe the molecular anatomy of a cell, and understand how an entire organism functions as a system? These are just some of the questions that scientists in a…
2009
science
Science Much as adrenaline coursing through our veins drives our body’s reactions to stress, the plant hormone abscisic acid (ABA) is behind plants’ responses to stressful situations such as drought, but how it does so has been a mystery for years. Scientists at the European Molecular Biology…
2009
science
Science Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.…
2009
science
Science For many years, the mosquitoes that transmit malaria to humans were seen as public enemies, and campaigns to eradicate the disease focused on eliminating the mosquitoes. But, as a study published today in Science shows, the mosquitoes can also be our allies in the fight against this common foe,…
2009
science
Science In the quest for speed, olympic swimmers shave themselves or squeeze into high-tech super-suits. In the body, sperm are the only cells that swim and, as speed is crucial to fertility, have developed their own ways to become exceptionally streamlined. Scientists at the European Molecular Biology…
2009
science
Science For scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, what seemed like a disappointing result turned out to be an important discovery. Their findings, published online this week in the journal Proceedings of the National Academy of Sciences (PNAS), provide…
2009
science
Science Stem cells have a unique ability: when they divide, they can either give rise to more stem cells, or to a variety of specialised cell types. In both mice and humans, a layer of cells at the base of the skin contains stem cells that can develop into the specialised cells in the layers above.…
2009
science
Lab Matters BBSRC has awarded funding to the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), based at Hinxton near Cambridge, to permit a dramatic increase in the institute’s data storage and handling capacity. The funding is the first step in developing the existing…
2009
lab-matters
Science Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer and other diseases. Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular ‘alarm bell’ to alert the…
2009
science
Science Chronic inflammatory lung diseases like chronic bronchitis and emphysema are a major global health problem, and the fourth leading cause of death and disability in developed countries, with smoking accounting for 90% of the risk for developing them. Work by scientists at the European Molecular…
2009
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have come a step closer to understanding how cholesterol levels are regulated. In a study published today in the journal Cell Metabolism, the researchers identified 20 genes that are involved…
2009
science
Lab Matters On June 26 2009 the joint international Unit for Virus and Host Cell Interactions (Unité Mixte Internationale) was formally established in Grenoble. The unit is run jointly by CNRS, the Grenoble outstation of the European Molecular Biology Laboratory (EMBL) and the Grenoble University Joseph…
2009
lab-matters
Science Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also during wound healing. Their study, published this week in the journal Cell, uncovers a fundamental…
2009
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is…
2009
science
Lab Matters Mice are one of biology’s most important model organisms, because 98% of their genes and many of their traits and diseases are similar to ours. Researchers at the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) take advantage of these similarities and use mice to study…
2009
lab-matters
Science The life sciences are scaling up and produce huge amounts of data and new literature at an amazing pace. The European Molecular Biology Laboratory (EMBL) now offers a new free service to help researchers, teachers and students keep up-to-date with scientific literature on the web, especially when…
2009
science
Science Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…
2009
science
Science Most cellular processes are carried out by molecular machines that consist of many interacting proteins. These protein complexes lie at the heart of life science research, but they are notoriously hard to study. Their abundance is often too low to extract them directly from cells and generating…
2009
science
Science Recycling is important not only on a global scale, but also at the cellular level, since key molecules tend to be available in limited numbers. This means a cell needs to have efficient recycling mechanisms. Researchers at the European Molecular Biology Laboratory (EMBL) and Heidelberg University,…
2009
science
Science It can be found in all life forms, and serves a multitude of purposes, from energy storage to stress response to bone calcification. This molecular jack-of-all trades is polyphosphate, a long chain of phosphate molecules. Researchers at the European Molecular Biology Laboratory (EMBL) in…
2009
science
Science ‘Useless fish with big eyes’. This is what Medaka, the name of the Japanese killifish in the pictures, means in Japan where it originally comes from. While its eyes are undeniably big, the fish has proven remarkably useful for scientists. It is a simple model organism, amenable to…
2009
science
Science Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light of looming pandemics if bird flu strains develop the ability to infect humans easily, new drugs and vaccines are desperately sought. Researchers at…
2009
science
Science Genes that contain instructions for making proteins make up less than 2% of the human genome. Yet, for unknown reasons, most of our genome is transcribed into RNA. The same is true for many other organisms that are easier to study than humans. Researchers in the groups of Lars Steinmetz at the…
2009
science
Lab Matters Microscope designer Leica Microsystems and the European Molecular Biology Laboratory (EMBL) signed a corporate partnership agreement today whereby Leica Microsystems becomes a founder partner of the EMBL Advanced Training Centre scheduled to be completed in September 2009. Besides its financial…
2008
lab-matters
Science Cell division is one of the most fundamental processes of life. It explains how one cell can give rise to an organism of several million cells, it determines the shape of different life forms and it underpins our body’s capacity to heal when injured. Often we only notice how important cell…
2008
science
Lab Matters The European Molecular Biology Laboratory (EMBL) and PerkinElmer Life and Analytical Sciences, a global leader in life science research, drug discovery and cellular science, today announced that they have entered into a corporate partnership in support of EMBL’s Advanced Training Centre in…
2008
lab-matters
Science The best-selling novel The swarm captured the imagination of countless readers with the fascination of marine life. But it also showed how little we understand life in the depth of the ocean. Scientists at the European Molecular Biology Laboratory (EMBL) and the Max Planck Institute (MPI)…
2008
science
Science What at the first sight could be pictures of planets or other cosmic structures are actually microscope images of balls (cysts) of human kidney cells. They were taken by Emmanuel Reynaud, in the group of Ernst Stelzer at the European Molecular Biology Laboratory (EMBL), with a widefield microscope.…
2008
science
Lab Matters Today at a meeting organised by the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, scientists from around the globe announced the formation of the International Human Microbiome Consortium (IHMC), an effort that will enable researchers to characterise the relationship of the…
2008
lab-matters
Science Researchers at the European Molecular Biology Laboratory (EMBL) have generated a digital zebrafish embryo – the first complete developmental blueprint of a vertebrate. With a newly developed microscope scientists could for the first time track all cells for the first 24 hours in the life of a…
2008
science
Lab Matters The Wellcome Trust has awarded £4.7 million (€5.8 million) to EMBL’s European Bioinformatics Institute (EMBL-EBI) to support the transfer of a large collection of information on the properties and activities of drugs and a large set of drug-like small molecules from the publicly listed…
2008
lab-matters
Science Mouse mothers-to-be have a remarkable way to protect their unborn pups. Because the smell of a strange male’s urine can cause miscarriage and reactivate the ovulatory cycle, pregnant mice prevent the action of such olfactory stimuli by blocking their smell. Researchers from the European…
2008
science
Science Researchers from the European Molecular Biology Laboratory (EMBL) discovered a new way to make use of drugs’ unwanted side effects. They developed a computational method that compares how similar the side effects of different drugs are and predicts how likely the drugs act on the same target…
2008
science
Science Genetic recombination, the process by which sexually reproducing organisms shuffle their genetic material when producing germ cells, leads to offspring with a new genetic make-up and influences the course of evolution. In the current issue of Nature, researchers at the European Molecular…
2008
science
Science Sudden Infant Death Syndrome (SIDS) is a condition that unexpectedly and unexplainably takes the lives of seemingly healthy babies aged between a month and a year. Now researchers of the European Molecular Biology Laboratory in Monterotondo, Italy, have developed a mouse model of the so-called crib…
2008
science
Science What makes a human different from a chimp? Researchers from the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) have come one important step closer to answering such evolutionary questions correctly. In the current issue of Science they uncover…
2008
science
Science Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that…
2008
science
Lab Matters In a contract signed today, the European Commission has awarded €4.5 million to a pan-European consortium to decide upon the best way to unite Europe’s biological data resources into a sustainable, integrative bioinformatics network for the life sciences. The European Life-science…
2008
lab-matters
Science UK-based researchers at the Medical Research Council Functional Genomics Unit in Oxford and the European Molecular Biology Laboratory’s European Bioinformatics Institute in Cambridge have revealed the genetic makeup of the one of the world’s strangest mammals. They have analysed the DNA…
2008
science
Science Influenza is currently a grave concern for governments and health organisations around the world. Now one of the tactics used by influenza virus to take over the machinery of infected cells has been laid bare by structural biologists at the EMBL, the joint Unit of Virus Host-Cell Interaction of…
2008
science
Science Leukaemia – cancer of blood or bone marrow – is caused by mutations that allow defective blood cells to accumulate and displace healthy blood. To devise effective therapies it is crucial to know which mutations cause leukaemia and which cell type gives rise to leukaemic cells. Researchers from…
2008
science
Science Epigenetic regulation – modifications to the structure of chromatin that influence which genes are expressed in a cell – is a key player in embryonic development and cancer formation. Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg now gained new insight…
2008
science
Science Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis [HH] has remained elusive. In a joint effort, researchers from the European Molecular…
2008
science
Lab Matters Drawing on the expertise of multi-disciplinary research teams, the map developed by the 1000 Genomes Project will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. The European Bioinformatics Institute (EBI), working with long-term collaborator…
2008
lab-matters
Science Researchers from the European Molecular Biology Laboratory (EMBL) have discovered that proteins that regulate the body’s iron household play a vital role in making sure enough nutrients and water are absorbed in the intestine. Mice lacking these proteins suffer from weight loss and…
2008
science
Science It does not take much to injure a muscle. Sometimes one sudden, inconsiderate movement does the job. Unfortunately, damaged muscles are not as efficient at repair as other tissues such as bone. Researchers of the European Molecular Biology Laboratory’s Mouse Biology Unit (EMBL), Italy, and…
2007
science
Lab Matters ArrayExpress, the publicly available database of transcriptomics data at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has doubled in size in 2007, reaching the 100,000-hybridisation milestone. The database now holds snapshots of gene expression…
2007
lab-matters
Science Seeing proteins in their natural environment and interactions inside cells has been a longstanding goal. Using an advanced microscopy technique called cryo-electron tomography, researchers from the European Molecular Biology Laboratory (EMBL) have visualised proteins responsible for cell-cell…
2007
science
Science Cells in our body come in various shapes and sizes. Each cell is shaped in such a way as to optimise it for a specific function. When things go wrong and a cell does not adopt its dedicated shape, its function can be impaired and the cell can cause problems in the body. Researchers at […]
2007
science
Lab Matters Today, the European Molecular Biology Laboratory (EMBL) announces Luxembourg as the new member of its international community. Accepted by EMBL’s council and ratified by the parliament of Luxembourg, the Grand-Duchy has officially joined the institute as the 20th member state. “EMBL is…
2007
lab-matters
Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) officially opens its new East Wing today with a reception for prominent guests. The East Wing will be jointly opened by Ian Pearson, Minister of State for Science and Innovation, UK, and Robert-Jan Smits,…
2007
lab-matters
Science New insights into the cellular signal chain through which pheromones stimulate mating in yeast have been gained by scientists at the European Molecular Biology Laboratory [EMBL]. Similar signal chains are found in humans, where they are involved in many important processes such as the…
2007
science
Lab Matters Today the European Molecular Biology Laboratory (EMBL), the University of Helsinki, Finland, the University of Oslo, Norway, and Umeå University, Sweden, officially launch their new Nordic EMBL Partnership for Molecular Medicine. The agreement will encourage scientific exchange and collaborations…
2007
lab-matters
Science Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly ─ a form of mental retardation ─ result from abnormal migration of nerve cells during the development of the brain. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy,…
2007
science
Science Scientists from the European Molecular Biology Laboratory (EMBL) have developed a new method to prepare and image biological samples in three dimensions with laser light-sheet based fluorescence microscopy. The technological advance, which is published in the current online issue of Nature…
2007
science
Lab Matters Three papers published by EMBL scientists and their collaborators will make it much easier to share and compare information from large-scale proteomics data. The papers are published in Nature Biotechnology on 8 and 26 August. As the quantity of available biological information and the use of…
2007
lab-matters
Science Which genes are passed on from mother to child is decided very early on during the maturation of the egg cell in the ovary. In a cell division process that is unique to egg cells, half of the chromosomes are eliminated from the egg before it is fertilised. Using a powerful microscope, researchers…
2007
science
Science The UniProt Consortium, which includes the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has added a new database repository for metagenomic and environmental data to its family of protein sequence databases. Metagenomics is the large-scale genomic…
2007
science
Lab Matters Today, delegates representing the 19 member states of the European Molecular Biology Laboratory (EMBL) offered Australia associate membership in EMBL’s international community. The membership is planned to start officially in January 2008 and will initially last for seven years. “EMBL…
2007
lab-matters
Science To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them. Using a…
2007
science
Science Researchers from the European Molecular Biology Laboratory (EMBL) and the University of Michigan have discovered a gene that protects us against a serious kidney disease. In the current online issue of Nature Genetics they report that mutations in the gene cause nephronopthisis (NPHP) in humans and…
2007
science
Science Hormones control growth, metabolism, reproduction and many other important biological processes. In humans, and all other vertebrates, the chemical signals are produced by specialised brain centres such as the hypothalamus and secreted into the blood stream that distributes them around the body.…
2007
science
Science A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory [EMBL] outstation in Grenoble, France. In the current issue of Science they describe…
2007
science
Science Scientists at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital (Canada), the European Molecular Biology Laboratory (Germany), and Massachusetts Institute of Technology (USA) have created a new computational method called NetworKIN. This method uses biological networks to better…
2007
science
Science The ENCyclopedia Of DNA Elements (ENCODE), an international research consortium organised by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today published the results of its exhaustive, four-year effort to build a “parts list” of…
2007
science
Science A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. These have to be copied and distributed equally into two daughter cells at every division. Condensation, the shortening of chromosomes, allows the cell to handle such huge amounts of genetic material during cell…
2007
science
Science Why does the same diet make some of us gain more weight than others? The answer could be a molecule called Bsx, as scientists from the European Molecular Biology Laboratory (EMBL), the German Institute for Nutrition (DIFE), Potsdam, and the University of Cincinnati report in the current issue of…
2007
science
Science People who suffer from anxiety tend to interpret ambiguous situations, situations that could potentially be dangerous but not necessarily so, as threatening. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy have now uncovered the neural basis for…
2007
science
Lab Matters It was the world’s earliest public database of DNA and RNA sequences and remains Europe’s primary nucleotide sequence resource. The database is maintained by EMBL’s European Bioinformatics Institute in Hinxton (UK) in collaboration with its US and Japanese counterparts GenBank and…
2007
lab-matters
Science Over 30% of our genes are under the control of small molecules called microRNAs. They prevent specific genes from being turned into protein and regulate many crucial processes like cell division and development, but how they do so has remained unclear. Now researchers from the European Molecular…
2007
science
Science When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers…
2007
science
Science The rise of the central nervous system (CNS) in animal evolution has puzzled scientists for centuries. Vertebrates, insects and worms evolved from the same ancestor, but their CNSs are different and were thought to have evolved only after their lineages had split during evolution. Researchers from…
2007
science
Science Inflammatory bowel diseases, such as Crohn’s disease and Ulcerative Colitis, severely impair the lives of more than four million people worldwide. The development of effective therapies against these diseases requires an understanding of their underlying molecular mechanisms. Researchers from…
2007
science
Science Like our body every cell has a skeleton that provides it with a shape, confers rigidity and protects its fragile inner workings. The cytoskeleton is built of long protein filaments that assemble into networks whose overall architecture and fine detail can only be revealed with high resolution…
2007
science
Science The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…
2007
science
Science In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around the world. There is great concern that this virus might also…
2007
science
Science Liver cancer is one of the deadliest cancers worldwide; every year sees more than 400,000 new cases, and most of the victims die in less than one year. Despite extensive research, the underlying molecular mechanisms of the disease are poorly understood. A new study by researchers from the Mouse…
2007
science
Science We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred. Researchers from the Innsbruck Medical…
2007
science
Science Microorganisms make up more than a third of the Earth’s biomass. They are found in water, on land and even in our bodies, recycling nutrients, influencing the planet’s climate or causing diseases. Still, we know surprisingly little about the smallest beings that colonise Earth. A new…
2007
science
Lab Matters The German Federal Ministry for Education and Research (BMBF) has awarded 8.8 Million Euro to the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) for the construction of an Integrated Research Facility for Structural Biology at the new PETRA-III storage ring of the German…
2007
lab-matters
Lab Matters The European Commission has awarded 3.7 Million Euro under the European Union Framework 6 Programme over the next four years to a new Marie Curie Research Training Network, coordinated by Dr. Andreas Ladurner at the European Molecular Biology Laboratory (EMBL). The long molecules of DNA that carry…
2007
lab-matters
Lab Matters From today scientists will be able to access a vast collection of biomedical research and to submit their own published results for inclusion in a new online resource. Based on a model currently used by the US National Institute of Health, UK PubMed Central (UKPMC) will provide free access to a…
2007
lab-matters
Science Phone numbers, the way to work, granny’s birthday – our brain with its finite number of nerve cells can store incredible amounts of information. At the bottom of memory lies a complex network of molecules. To understand how this network brings about one of the most remarkable capacities of…
2007
science
Science A cell is a busy place. In a permanent rush hour, molecules are transported along a dynamic motorway system made up of filaments called microtubules. Microtubules constantly grow and shrink and are rapidly assembled wherever a cargo needs to go, but during this transportation process they need to…
2006
science
Lab Matters Today, Janez Potočnik, European Commissioner for Science and Research, received a statement of support for the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers from EIROforum. “The EIROforum partners warmly welcome this valuable initiative by…
2006
lab-matters
Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches its new, faster and easier website with an exhaustive search engine at its centre. The web interface has been streamlined on the basis of user feedback from a recent extensive…
2006
lab-matters
Lab Matters The BioModels Database, hosted by the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) in Cambridge, UK, has entered a formal data-exchange agreement with the Database of Quantitative Chemical Signalling (DOQCS) of the National Centre for…
2006
lab-matters
Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches CiteXplore, a new freely accessible literature resource service. Biological researchers require two crucial sources of information: scientific literature published in peerreviewed…
2006
lab-matters
Science Muscle wasting can occur at all ages as the result of genetic defects, heart failure, spinal injury or cancer. A therapy to cure the loss of muscle mass and strength, which has a severe impact on patients’ lives, is desperately sought. Blocking a central signal molecule, researchers from the…
2006
science
Lab Matters Today, the German Minister for Education and Research, Annette Schavan, breaks ground for the new training and conference centre for the life sciences that will be built on the EMBL campus in Heidelberg. The German Ministry for Education and Research (BMBF), the Klaus Tschira…
2006
lab-matters
Science The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. A control system with several layers adjusts when key components of the cell cycle machinery are produced, activated and degraded to make sure…
2006
science
Lab Matters Today the European Molecular Biology Laboratory (EMBL), the Centre for Genomic Regulation (CRG) and the Spanish Ministry for Education and Science (MEC) officially launch their new joint EMBL/CRG Research Unit in Systems Biology on the campus of the Barcelona Biomedical Research Park. The Spanish…
2006
lab-matters
Science Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves and turning these into the blood cell types needed by the body. Claus Nerlov and his colleagues at the European Molecular Biology Laboratory (EMBL) unit in Monterotondo, Italy, in…
2006
science
Science Eyes are among the earliest recognisable structures in an embryo; they start off as bulges on the sides of tube-shaped tissue that will eventually become the brain. Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg have now discovered that cells are programmed to make…
2006
science
Science Cells in an embryo divide at an amazing rate to build a whole body, but this growth needs to be controlled. Otherwise the result may be defects in embryonic development or cancer in adults. Controlling growth requires that some cells divide while others die; their fates are determined by signals…
2006
science
Lab Matters Today EMBL scientists, EMBL’s commercial affiliate, EMBL Enterprise Management Technology Transfer GmbH (EMBLEM) and EMBL’s venture vehicle, EMBL Ventures GmbH, announce the foundation of Elara Pharmaceuticals GmbH, a start-up company that will translate basic research findings into new…
2006
lab-matters
Science Depression, coordination and speech problems, muscle weakness and disability are just a few of the symptoms of Multiple Sclerosis (MS). Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy and the Department of Neuropathology at the Faculty of…
2006
science
Lab Matters Scientists will be able to access a vast collection of biomedical research at the touch of a button thanks to a major new initiative that aims to promote the free transfer of ideas in a bid to speed up scientific discovery. Based on a model currently used in the United States, UK PubMed Central…
2006
lab-matters
Lab Matters In the early days of X-ray crystallography obtaining a three-dimensional model of a protein required wire models, screws, bolts and years of tedious calculations by hand. Today macromolecular models are built by computers – thanks to sophisticated software and in particular a package called…
2006
lab-matters
Lab Matters Croatia has officially joined the European Molecular Biology Laboratory (EMBL) as the organisation’s 19th Member State. The Croatian parliament ratified its membership after EMBL’s council had accepted the country’s application. “Joining EMBL is a very important step…
2006
lab-matters
Science Ebola, measles and rabies are serious threats to public health in developing countries. Despite different symptoms all of the diseases are caused by the same class of viruses that unlike most other living beings carry their genetic information on a single RNA molecule instead of a double strand of…
2006
science
Science Tuberculosis remains one of the deadliest threats to public health. Every year two million people die of the disease, which is caused by the microorganism Mycobacterium tuberculosis. Roughly one third of the world’s population is infected and more and more bacterial strains have developed…
2006
science
Lab Matters Today the European Molecular Biology Laboratory’s (EMBL) European Bioinformatics Institute (EBI), the Swiss Institute for Bioinformatics (SIB), the University of Cologne, Germany, and the European Patent Office launch FELICS (Free European Life-science Information and Computational Services).…
2006
lab-matters
Lab Matters EMBOSS, the European Molecular Biology Open Software Suite, has received a vital funding boost from the UK Biotechnology and Biological Sciences Research Council (BBSRC) that will guarantee its continued maintenance under an open source license for the next three years. This ends two years of…
2006
lab-matters
Lab Matters Today three research organisations announce the merging of their expertise to fight cardiovascular diseases, which are among the most common health problems and causes of death in the world. The Magdi Yacoub Institute (MYI) at the UK’s Harefield Heart Science Centre, Imperial College London,…
2006
lab-matters
Events Today the network of excellence for Biology and Pathology of the Malaria Parasite (BioMalPar), will bring together the world’s elite in the field of Malaria research at the European Molecular Biology Laboratory (EMBL) in Heidelberg. At the second annual BioMalPar conference, organised jointly…
2006
events
Lab Matters Science is moving more rapidly than ever; one groundbreaking discovery chases the next at an incredible speed. School teachers have trouble keeping up with the pace, and many pupils call science classes “boring”. Today, Europe’s major research organisations launch Science in…
2006
lab-matters
Science Recent research at the European Molecular Biology Laboratory (EMBL) reveals new insights into how cells achieve equality between the sexes. A new link discovered between the membrane surrounding the nucleus and the male X-chromosome in fruit flies may play a crucial role in determining how active…
2006
science
Science In 1870 the German scientist Ernst Haeckel mapped the evolutionary relationships of plants and animals in the first ‘tree of life’. Since then scientists have continuously redrawn and expanded the tree adding microorganisms and using modern molecular data, yet, many parts of the tree…
2006
science
Science A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institut de Virologie Moléculaire et Structurale (IVMS), associated with the…
2006
science
Science Today researchers in Germany announce they have finished the first complete analysis of the “molecular machines” in one of biology’s most important model organisms: S. cerevisiae (baker’s yeast). The study from the biotechnology company Cellzome, in collaboration with the…
2006
science
Science Imagine grabbing two snakes by the tail so that they can’t wriggle off in opposite directions. Scientists at the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) and collaborators from King’s College in London have now discovered that something similar happens to a…
2006
science
Lab Matters On Friday, 13 January 2006, the new Carl-Ivar Brändén Building (CIBB) will be inaugurated on the Polygone Scientifique Campus in Grenoble, France. The CIBB will be operated as a collaboration between major international and national partners based in Grenoble and is a further step in the…
2006
lab-matters
Science Researchers at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in India and a unit of the European Molecular Biology Laboratory (EMBL) in France have made a key discovery about a molecule that helps the malaria parasite infect human cells. India is one of the countries…
2005
science
Lab Matters In the December 6 issue of Nature Biotechnology, scientists from 14 different organizations around the world, including the EMBL-European Bioinformatics Institute, propose a new quality standard for biochemical models. MIRIAM [for Minimum information requested in the annotation of biochemical…
2005
lab-matters
Science Species evolve at very different rates, and the evolutionary line that produced humans seems to be among the slowest. The result, according to a new study by scientists at the European Molecular Biology Laboratory [EMBL], is that our species has retained characteristics of a very ancient ancestor…
2005
science
Lab Matters Today the European Molecular Biology Laboratory (EMBL) opens a new highthroughput crystallization facility at its Outstation located on the campus of the German Synchrotron Radiation Facility (DESY) in Hamburg, Germany. The facility, made possible by major funds from the German Ministry for Science…
2005
lab-matters
Science Most of what happens in cells is the work of machines that contain dozens of molecules, chiefly proteins. With the completion of human and other genomes, researchers now have a nearly complete ‘parts list’ of such machines; what’s lacking is the manual telling where all the pieces…
2005
science
Science Scientists at the Universities of Heidelberg and Ulm and a unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have discovered that a specific signal within brain cells may determine whether they live or die after a stroke. Their study, published online (November 13) by…
2005
science
Lab Matters The Commission of the European Union has awarded EUR 9 million over five years for a new Network of Excellence that will make computational systems biology accessible to bench scientists throughout Europe and beyond. ENFIN, which stands for ‘Experimental Network for Functional…
2005
lab-matters
Science Mutations in genes are the basis of evolution, so we owe our existence to them. Most mutations are harmful, however, because they cause cells to build defective proteins. So cells have evolved quality control mechanisms that recognize and counteract genetic mistakes. Now scientists of the Molecular…
2005
science
Lab Matters The European Commission has selected the EBI to coordinate a project that will stimulate and explore synergies between bioinformatics (the science of storing, retrieving and analysing large amounts of biological information) and medical informatics (the science of processing, sharing and using…
2005
lab-matters
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells. The study, reported this week in…
2005
science
Lab Matters The European Bioinformatics Institute and Flanders Interuniversity Institute for Biotechnology (VIB) – Ghent University have launched the PRoteomics IDEntifications database (PRIDE). PRIDE allows researchers who work in the field of proteomics – the large-scale study of proteins – to…
2005
lab-matters
Lab Matters The executive teams of five major molecular interaction databases announced today the signing of an agreement to share curation efforts and exchange completed records through a mechanism known as the International Molecular Exchange (IMEx) consortium. IMEx will provide a network of stable,…
2005
lab-matters
Science Achieving equality between the sexes can be a challenge even for single cells. Since evolution began removing bits of male DNA to create the ‘Y’ chromosome, males have had a single copy of certain key genes on the X chromosome, whereas females have two. Normally this would lead females…
2005
science
Lab Matters The world’s three leading public repositories for DNA and RNA sequence information have reached 100 gigabases (100,000,000,000 bases; the ‘letters’ of the genetic code) of sequence. Thanks to their data exchange policy, which has paved the way for the global exchange of many types…
2005
lab-matters
Lab Matters The first rate research from the Molecular Medicine Partnership Unit (MMPU) is now set to continue for the long-term. The European Molecular Biology Laboratory (EMBL) and the Medical Faculty of University of Heidelberg, who formed the joint venture in 2002, have announced their plans to initiate a…
2005
lab-matters
Science Microtubules need a helping hand to find chromosomes in dividing egg cells, scientists have discovered. Although it was generally accepted that microtubules act alone as the cellular ropes to pull chromosomes into place, a new study by researchers at the European Molecular Biology Laboratory (EMBL)…
2005
science
Lab Matters A systematic search through human genes has begun at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Working within the MitoCheck consortium that includes 10 other institutes throughout Europe, the EMBL scientists will silence all human genes, one-by-one, to find those…
2005
lab-matters
Science EBI researchers have changed our view of 4 billion years of microbial evolution. Christos Ouzounis and colleagues have gained intriguing quantitative insights into how gene families are transferred, not only ‘vertically’ through passage from one organism to its progeny, but also…
2005
science
Science Living organisms need to sense the amount of energy that is available to them and regulate the activity of their genes accordingly. Scientists have made the unexpected finding that a histone protein, which wraps DNA into tight bundles and regulates gene activity, can bind a small molecule produced…
2005
science
Lab Matters The European Bioinformatics Institute (EMBL-EBI) has received a big boost from The Wellcome Trust, the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC), who have given funds to expand the EBI site in Hinxton, Cambridgeshire, UK. The new…
2005
lab-matters
Lab Matters Dr. Iain Mattaj today took over the leadership of the European Molecular Biology Laboratory [EMBL], a prominent basic research and training institute with laboratories in France, Germany, Italy and the UK. “The pace of progress in the life sciences is remarkable. I see my job as ensuring that…
2005
lab-matters
Science Instead of sequencing the genome of one organism, why not sequence a drop of sea water, a gram of farm soil or even a sunken whale skeleton? Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and their US collaborators have done just that, and the result is a new…
2005
science
Science Today sees the launch of BioModels, the world’s first database of annotated biological models. BioModels is the result of a collaboration led by the European Bioinformatics Institute (UK) and the SBML Team, an international group that develops opensource standards to describe biological…
2005
science
Lab Matters A novel high-tech microscope will be brought to the marketplace, giving laboratories everywhere fascinating new insights into living organisms. EMBLEM Technology Transfer GmbH (EMBLEM), the commercial entity of the European Molecular Biology Laboratory (EMBL), announced today that it has signed a…
2005
lab-matters
Lab Matters The International Society for Computational Biology has named two scientists from the European Bioinformatics Institute as the winners of its awards for 2005. Janet Thornton wins the Senior Scientist Accomplishment Award while the Overton Prize goes to Ewan Birney. Thomas Lengauer, the ISCB’s…
2005
lab-matters
Science Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…
2005
science
Lab Matters The Commission of the European Union has awarded 8.3 million Euro to a pan-European task force who will improve access to biological information for scientists throughout and beyond Europe. The EMBRACE Network of Excellence, which encompasses computational biologists from 17 institutes in 11…
2005
lab-matters
Science One of the most basic yet least understood processes in our bodies is how cells crawl along tissues. This behavior is essential to the formation of an embryo and other processes, but it must be tightly controlled. A disturbance can lead to the spread of cancer cells or diseases like Spina…
2005
science
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